Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation

Pathogen Recognition and Innate Immunity

Akira, S., Uematsu, S., & Takeuchi, O. (2006) · Cell · doi:10.1016/j.cell.2006.02.015 · Cited by 12,401

The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology

Bedard, K., & Krause, K.-H. (2007) · Physiological Reviews · doi:10.1152/physrev.00044.2005 · Cited by 6,989

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

The International Multiple Sclerosis Genetics Consortium & The Wellcome Trust Case Control Consortium 2 (2011) · Nature · doi:10.1038/nature10251 · Cited by 2,697

Psoriasis

Boehncke, W., & Schön, M. P. (2015) · The Lancet · doi:10.1016/s0140-6736(14)61909-7 · Cited by 2,609

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

Baechler, E. C., Batliwalla, F., Karypis, G., Gaffney, P. M., Ortmann, W. A., Espe, K. J., Shark, K. B., Grande, W. J., Hughes, K. M. H., Kapur, V., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337679100 · Cited by 2,246

Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

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Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus Blood

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Mitochondrial DNA stress primes the antiviral innate immune response

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Redox regulation of cell survival

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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

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Neutrophil Cytosolic Factor 1 Contributes to the Development of Sepsis

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Bioinformatics analysis based on microarray data reveals molecular crosstalk and immune relationship between sarcopenia and atherosclerosis

Yang, J., Zhong, J., Du, Y., Liu, J., Li, Z., & Liu, Y. (2025) · Experimental Gerontology · doi:10.1016/j.exger.2025.112811 · Cited by 4

Inflammation, symptoms, benefits, reaction, and biochemistry

Nair, A., Thankachen, R. U., Raj, J., & Gopi, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819218-4.00003-1 · Cited by 3

Genetic component of autoimmune rheumatological diseases

Juárez-Melchor, D., Munguía‐Realpozo, P., Pinto, C. M., Etchegaray‐Morales, I., Ayón-Aguilar, J., Méndez‐Martínez, S., García‐Carrasco, M., & Arriola, J. G. (2021) · Reumatología Clínica (English Edition) · doi:10.1016/j.reumae.2021.08.001 · Cited by 3

A missense variant in NCF1 is associated with susceptibility to unexplained recurrent spontaneous abortion

Du, M., Gu, H., Li, Y., Huang, L., Gao, M., Xu, H., Deng, H., Zhong, W., Liu, X., & Zhong, X. (2022) · Open Life Sciences · doi:10.1515/biol-2022-0518 · Cited by 3

Immunogenetics of Lupus Erythematosus

Ünlü, B., Türsen, Ü., Jabalameli, N., Abdollahimajd, F., & Rajabi, F. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-92616-8_9 · Cited by 4

Gene modification: Exploring the potential in treating kidney diseases

Ekperikpe, U. S., Zhao, S., & Daehn, I. S. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.108104 · Cited by 3

Glycan Activation of Clec4b Induces Reactive Oxygen Species Protecting against Neutrophilia and Arthritis

Aoun, M., Cai, X., Xu, B., Lahore, G. F., Bonner, M. Y., He, Y., Bäckdahl, L., & Holmdahl, R. (2021) · Antioxidants · doi:10.3390/antiox11010012 · Cited by 3

Impact of psoriasis disease and its treatment with Etanercept on serum and saliva thiol-disulfide homeostasis

Hasan, H. R., & Rasul, R. A. (2022) · Egyptian Journal of Chemistry · doi:10.21608/ejchem.2022.150769.6530 · Cited by 2

Targeting the V-Type Immunoglobulin Domain-Containing Suppressor to T Cell Activation (VISTA) with Agonist Monoclonal Antibodies in Autoimmunity

Jung, M., & Bonavida, B. (2022) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.2023047591 · Cited by 2

Biomaterials for Induction and Treatment of Autoimmunity

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Significance of Oxidative Stress in the Diagnosis and Subtype Classification of Intervertebral Disc Degeneration

Gu, J., Zhou, X., & Xie, L. (2023) · Biochemical Genetics · doi:10.1007/s10528-023-10412-x · Cited by 2

Effects of Soy Bread on Cardiovascular Risk Factor, Inflammation and Oxidative Stress in Women With Active Rheumatoid Arthritis: A Randomized Double-Blind Controlled Trial

Sayyaf, A., Ghaedi, E., Haidari, F., Rajaei, E., Engali, K. A., & Helli, B. (2024) · Clinical Nutrition Research · doi:10.7762/cnr.2024.13.1.22 · Cited by 2

Redox Regulation of LAT Enhances T Cell-Mediated Inflammation

James, J. R., Coelho, A., Lahore, G. F., Hernandez, C. M., Forster, F., MALISSEN, B., & Holmdahl, R. (2024) · Antioxidants · doi:10.3390/antiox13040499 · Cited by 2

Association of autophagy to the phenotypic transformation of synovial fibroblasts in rheumatoid arthritis

Kondo, N. (2022) · Annals of Translational Medicine · doi:10.21037/atm-22-4734 · Cited by 2

Spatially resolved single cell analysis suggests an APOE NCF1 associated immunosuppressive niche and its prognostic signature in thyroid cancer

Su, H., Zhang, Z., Li, N., Zhang, Z., Zhang, R., Li, Z., Chen, F., Wang, X., Zhang, S., & Zhang, C. (2026) · Discover Oncology · doi:10.1007/s12672-026-05061-6 · Cited by 1

Novel aspects of the activation of NADPH oxidase in neutrophils of rheumatic patients on biological therapy

Jančinová, V., Drábiková, K., Killinger, Z., Pažoureková, S., Nosáľ, R., & Payer, J. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.02.015 · Cited by 1

The effect of soy and soy product supplementation on circulating adiponectin and leptin concentration: A systematic review and meta‐analysis of randomized controlled trialsPreprint

farokhzad, A., & Marx, W. (2020) · doi:10.22541/au.159985403.31041118 · Cited by 1

Comparative Analysis of Association Networks Using Single-Cell RNA Sequencing Data Reveals Perturbation-Relevant Gene SignaturesPreprint

Nouri, N., Gaglia, G., Mattoo, H., de Rinaldis, E., & Savova, V. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.11.556872 · Cited by 1

Reactive oxygen species in protein sulphenic acid formation during T cell activation; implications for rheumatoid arthritis

Remtulla, A. H. (2019) · Aston Publications Explorer (Aston University) · doi:10.48780/publications.aston.ac.uk.00041270

Positional cloning of polymorphic loci that control autoreactive T cells

Aoun, M. (2021) · Figshare

Data from Idelalisib Rescues Natural Killer Cells from Monocyte-Induced Immunosuppression by Inhibiting NOX2-Derived Reactive Oxygen Species

Akhiani, A. A., Hallner, A., Kiffin, R., Aydin, E., Werlenius, O., Aurelius, J., Martner, A., Thorén, F. B., & Hellstrand, K. (2023) · doi:10.1158/2326-6066.c.6550396

Data from Idelalisib Rescues Natural Killer Cells from Monocyte-Induced Immunosuppression by Inhibiting NOX2-Derived Reactive Oxygen Species

Akhiani, A. A., Hallner, A., Kiffin, R., Aydin, E., Werlenius, O., Aurelius, J., Martner, A., Thorén, F. B., & Hellstrand, K. (2023) · doi:10.1158/2326-6066.c.6550396.v1

Connecting intermediate phenotypes to disease using multi-omics in heart failurePreprint

Moore, A. K., Venkatesh, R., Levin, M. G., Damrauer, S. M., Reza, N., Cappola, T. P., & Ritchie, M. D. (2024) · medRxiv · doi:10.1101/2024.08.06.24311572

Cellular Inflammation‐Induced Cleavage of Phosphorothioate DNA Locker Activates CRISPR/Cas9 Regulator for Gene Editing

Sha, R., Qin, H., Yuan, A., Deng, Z., Liao, W., Qu, G., Wen, B., Xie, W., & Peng, H. (2025) · Chemistry - An Asian Journal · doi:10.1002/asia.202401696

Les opioïdes : un verrou à la régénération chez le mammifère adulte ? Dialogue avec le système immunitaire et l'innervation sensorielle

Rabiller, L. (2020) · theses.fr (ABES) · doi:10.70675/672b0e2ezef3bz4593za5a2ze1aec6c30175

Reactive species as regulators of immune cell metabolism, tolerance, and autoimmunity

Kobayashi, T., & Brenner, D. (2026) · Cell Metabolism · doi:10.1016/j.cmet.2026.06.002

NCF1 aggravates cerebral ischemia-reperfusion injury by amplifying NOX2-Dependent oxidative stress and inflammatory responses

Wang, Z., Cong, Y., Huang, H., Huiqiong, S., Peng, X., & Cheng, J. (2026) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2026.154241

Human Transcriptomic Meta-Analysis Identifies Immune-Redox Remodeling and Impaired Vascular Wall Homeostasis in Abdominal Aortic Aneurysm

Engel, M., Voskamp, S., McIntosh, M., Akins, R. E., Park, H. P., & Nelson, J. S. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27167257 · Cited by 1

Exploratory longitudinal analysis of a PIN1-associated gene panel in PBMCs during orbital spaceflight

Taştan, C., Uzun, Z. B., Yıldırım, C., & Aydin, B. (2026) · Havacılık ve Uzay Çalışmaları Dergisi · doi:10.52995/jass.1921118

Clinical Risk Stratification and Neutrophil‐Mediated Neuroinflammation in Myeloid Hypertension‐Like Syndrome: An Integrated Clinical and Single‐Cell Transcriptomic Study

Shang, Q., Luan, H., Han, P., Wang, X., Zheng, J., Wang, X., & Song, X. (2026) · International Journal of Clinical Practice · doi:10.1155/ijcp/1311311

Association of NOX2 subunits genetic variants with autoimmune diseases

Zhong, J., Olsson, L. M., Urbonaviciute, V., Yang, M., Bäckdahl, L., & Holmdahl, R. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.03.005 · Cited by 63

A Reduction in Intracellular Reactive Oxygen Species Due to a Mutation in NCF4 Promotes Autoimmune Arthritis in Mice

Winter, S., Hopkins, M. H., Laulund, F., & Holmdahl, R. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6675 · Cited by 40

The Role of Reactive Oxygen Species in Animal Models of Autoimmunity

Hultqvist, M. H. (2007) · Lund University Publications (Lund University)

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms

Sareila, O., Hagert, C., Kelkka, T., Linja, M., Xu, B., Kihlberg, J. O., & Holmdahl, R. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6981 · Cited by 25

Conditional model to study the tissue- and time specific effects of nadph oxidase 2 -derived reactive oxygen species during arthritis

Sareila, O., Rantakari, P., POUTANEN, M. H., & Holmdahl, R. (2012) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2011-201238.27