The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Review article: 13C‐urea breath test in the diagnosis of Helicobacter pylori infection – a critical review
Abstract
Summary: The urea breath test is a non‐invasive, simple and safe test which provides excellent accuracy both for the initial diagnosis of Helicobacter pylori infection and for the confirmation of its eradication after treatment. Some studies have found no differences between urea breath test performed under non‐fasting conditions. The simplicity, good tolerance and economy of the citric acid test meal probably make its systematic use advisable. The urea breath test protocol may be performed with relatively low doses (<100 mg) of urea: 75 mg or even 50 mg seem to be sufficient. With the most widely used protocol (with citric acid and 75 mg of urea), excellent accuracy is obtained when breath samples are collected as early as 10–15 min after urea ingestion. A unique and generally proposed cut‐off level is not possible because it has to be adapted to different factors, such as the test meal, the dose and type of urea, or the pre‐/post‐treatment setting. Fortunately, because positive and negative urea breath test results tend to cluster outside of the range between 2 and 5‰, a change in cut‐off value within this range would be expected to have little effect on clinical accuracy of the test.
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Malfertheiner, P., Mégraud, F., O'Morain, C., Hungin, A. P. S., Jones, R., Axon, A., Graham, D. Y., Tytgat, G., & The European Helicobacter Pylori Study Group (EHPSG) (2002) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2002.01169.x · Cited by 1,237
CAMPYLOBACTER PYLORI DETECTED NONINVASIVELY BY THE 13C-UREA BREATH TEST
Graham, D., Evans, D., Alpert, L., Klein, P., Evans, D., Opekun, A., & Boutton, T. (1987) · The Lancet · doi:10.1016/s0140-6736(87)92145-3 · Cited by 711
The role of internal urease in acid resistance of Helicobacter pylori
Scott, D. R., Weeks, D., Hong, C., Postius, S., Melchers, K., & Sachs, G. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70633-x · Cited by 284
Schoeller, D. A., Klein, P. D., Watkins, J. B., Heim, T., & MacLean, W. C. (1980) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/33.11.2375 · Cited by 222
The 13 C urea breath test in the diagnosis of Helicobacter pylori infection
Savarino, V, Vigneri, S., & Celle, G. (1999) · Gut · doi:10.1136/gut.45.2008.i18 · Cited by 186
Domínguez‐Muñoz, J. E., Leodolter, A., Sauerbruch, T., & Malfertheiner, P. (1997) · Gut · doi:10.1136/gut.40.4.459 · Cited by 167
Carbon 13–labeled urea breath test for the diagnosis of Helicobacter pylori infection in children
Rowland, M., Lambert, I., Gormally, S., Daly, L. E., Thomas, J. E., Hetherington, C., Durnin, M., & Drumm, B. (1997) · The Journal of Pediatrics · doi:10.1016/s0022-3476(97)70026-x · Cited by 166
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Gatta, L., Vakil, N. B., Ricci, C., Osborn, J. F., Tampieri, A., Perna, F., Miglioli, M., & Vaira, D. (2004) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.30162.x · Cited by 141
Vandenplas, Y., Blecker, U., Devreker, T., et al. (1992) · PEDIATRICS · doi:10.1542/peds.90.4.608 · Cited by 140
Cited by
Management of Helicobacter pylori infection—the Maastricht IV/ Florence Consensus Report
Malfertheiner, P., Megraud, F., O'Morain, C. A., Atherton, J., Axon, A. T. R., Bazzoli, F., Gensini, G. F., Gisbert, J. P., Graham, D. Y., Rokkas, T., et al. (2012) · Gut · doi:10.1136/gutjnl-2012-302084 · Cited by 2,266
Self-citationMalfertheiner, P., Megraud, F., O'Morain, C., Bazzoli, F., El-Omar, E., Graham, D., Hunt, R., Rokkas, T., Vakil, N., Kuipers, E. J., et al. (2007) · Gut · doi:10.1136/gut.2006.101634 · Cited by 2,240
Second Asia–Pacific Consensus Guidelines for Helicobacter pylori infection
Fock, K. M., Katelaris, P., Sugano, K., Ang, T. L., Hunt, R., Talley, N. J., Lam, S. K., Xiao, S., Tan, H. J., Wu, C., et al. (2009) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2009.05982.x · Cited by 554
Diagnosis of Helicobacter pylori infection: Current options and developments
Wang, Y.-K. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i40.11221 · Cited by 466
Fifth Chinese National Consensus Report on the management of Helicobacter pylori infection
Liu, W. Z., Xie, Y., Lu, H., Cheng, H., Zeng, Z. R., Zhou, L. Y., Chen, Y., Wang, J. B., Du, Y. Q., Lu, N. H., et al. (2018) · Helicobacter · doi:10.1111/hel.12475 · Cited by 422
Metadata
- Authors
- Gisbert, J. P., & Pajares, J. M.
- Venue
- Alimentary Pharmacology & Therapeutics
- Publisher
- Wiley
- Published
- 2004-11
- Volume
- 20
- Issue
- 10
- Pages
- 1001-1017
- ISSN
- 0269-2813 (ISSN-L)
- 1365-2036
- OpenAlex
- W1989131633
- Cited by
- 374
- References
- 44
- FWCI
- 13.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Review article: 13C‐urea breath test in the diagnosis of Helicobacter pylori infection – a critical review. https://app.cochat.ai/papers/10.1111/j.1365-2036.2004.02203.x
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- Gisbert, J. P., & Pajares, J. M. (2004). Review article: 13C‐urea breath test in the diagnosis of Helicobacter pylori infection – a critical review. Alimentary Pharmacology & Therapeutics. https://doi.org/10.1111/j.1365-2036.2004.02203.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
