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Cited by 466

The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.

Diagnosis of Helicobacter pylori infection: Current options and developments

Open access
Wang, Yao-Kuang·2015·World Journal of Gastroenterology

Abstract

Accurate diagnosis of Helicobacter pylori (H. pylori) infection is a crucial part in the effective management of many gastroduodenal diseases. Several invasive and non-invasive diagnostic tests are available for the detection of H. pylori and each test has its usefulness and limitations in different clinical situations. Although none can be considered as a single gold standard in clinical practice, several techniques have been developed to give the more reliable results. Invasive tests are performed via endoscopic biopsy specimens and these tests include histology, culture, rapid urease test as well as molecular methods. Developments of endoscopic equipment also contribute to the real-time diagnosis of H. pylori during endoscopy. Urea breathing test and stool antigen test are most widely used non-invasive tests, whereas serology is useful in screening and epidemiological studies. Molecular methods have been used in variable specimens other than gastric mucosa. More than detection of H. pylori infection, several tests are introduced into the evaluation of virulence factors and antibiotic sensitivity of H. pylori, as well as screening precancerous lesions and gastric cancer. The aim of this article is to review the current options and novel developments of diagnostic tests and their applications in different clinical conditions or for specific purposes.

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Metadata

Authors
Wang, Y.-K.
Venue
World Journal of Gastroenterology
Published
2015
Volume
21
Issue
40
Pages
11221
ISSN
1007-9327 (ISSN-L)
OpenAlex
W2412375869
Cited by
466
References
58
FWCI
19.09
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Diagnosis of Helicobacter pylori infection: Current options and developments. https://app.cochat.ai/papers/10.3748/wjg.v21.i40.11221
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Wang, Y.-K. (2015). Diagnosis of Helicobacter pylori infection: Current options and developments. World Journal of Gastroenterology. https://doi.org/10.3748/wjg.v21.i40.11221

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.