The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Anaesthesia in haemodynamically compromised emergency patients: does ketamine represent the best choice of induction agent?
Abstract
Summary: In rapid sequence induction of anaesthesia in the emergency setting in shocked or hypotensive patients (e.g. ruptured abdominal aortic aneurysm, polytrauma or septic shock), prior resuscitation is often suboptimal and comorbidities (particularly cardiovascular) may be extensive. The induction agents with the most favourable pharmacological properties conferring haemodynamic stability appear to be ketamine and etomidate. However, etomidate has been withdrawn from use in some countries and impairs steroidogenesis. Ketamine has been traditionally contra‐indicated in the presence of brain injury, but we argue in this review that any adverse effects of the drug on intracranial pressure or cerebral blood flow are in fact attenuated or reversed by controlled ventilation, subsequent anaesthesia and the greater general haemodynamic stability conferred by the drug. Ketamine represents a very rational choice for rapid sequence induction in haemodynamically compromised patients.
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Cited by
Ketamine use in current clinical practice
Gao, M., Rejaei, D., & Liu, H. (2016) · Acta Pharmacologica Sinica · doi:10.1038/aps.2016.5 · Cited by 286
The Physiologically Difficult Airway
Mosier, J., Joshi, R., Hypes, C., Pacheco, G., Valenzuela, T., & Sakles, J. (2015) · Western Journal of Emergency Medicine · doi:10.5811/westjem.2015.8.27467 · Cited by 265
Risdall, J. E., & Menon, D. K. (2011) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2010.0230 · Cited by 185
Ketamine applications beyond anesthesia – A literature review
Nowacka, A., & Borczyk, M. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172547 · Cited by 129
Management of the airway in multitrauma
Dupanovic, M., Fox, H., & Kovac, A. (2010) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0b013e3283360b4f · Cited by 39
Metadata
- Authors
- Morris, C., Perris, A., Klein, J., & Mahoney, P.
- Venue
- Anaesthesia
- Publisher
- Wiley
- Published
- 2009-04-07
- Volume
- 64
- Issue
- 5
- Pages
- 532-539
- ISSN
- 0003-2409 (ISSN-L)
- 1365-2044
- OpenAlex
- W1975790248
- Cited by
- 215
- References
- 1
- FWCI
- 13.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- Morris, C., Perris, A., Klein, J., & Mahoney, P. (2009). Anaesthesia in haemodynamically compromised emergency patients: does ketamine represent the best choice of induction agent? Anaesthesia. https://doi.org/10.1111/j.1365-2044.2008.05835.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
