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Cited by 78Cutaneous Melanoma Detection and Managementmelanin and skin pigmentationCancer and Skin Lesions

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Micro-melanoma detection: a clinical study on 206 consecutive cases of pigmented skin lesions with a diameter ≤ 3 mm

Bono, A., Tolomio, E., Trincone, S., Bartoli, C., Tomatis, S., Carbone, A., Santinami, M.·2006·British Journal of Dermatology
DOI 10.1111/j.1365-2133.2006.07396.x
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Abstract

BACKGROUND: Very small pigmented lesions may represent an important diagnostic challenge to the clinician. OBJECTIVES: The aim of the present study was to establish the diagnostic value, in terms of sensitivity and specificity, of both clinical and dermoscopic examinations in a population of patients with unselected consecutive pigmented lesions with a maximum clinical diameter of 3 mm. PATIENTS AND METHODS: Two hundred and four consecutive patients bearing 206 pigmented skin lesions with a maximum diameter of 3 mm were seen and operated on. Twenty-three of these lesions were melanomas. Each lesion was subjected to both clinical and dermoscopic evaluation before surgery. The results were expressed in terms of sensitivity and specificity of both kinds of evaluation. RESULTS: Clinical evaluation produced a diagnostic sensitivity of 43% and a specificity of 91%. Dermoscopy resulted in a sensitivity of 83% and in a specificity of 69%. The comparison between the sensitivity values of the two diagnostic methods showed a significant difference (P < 0.01). A high value of significance was also obtained comparing the respective specificity values (P < 0.001). CONCLUSIONS: Detection of very small melanomas is feasible by accurate visual inspection. Dermoscopy appears to be an important aid to diagnosis, provided that physicians are aware of this type of lesion and maintain the index of suspicion at a high level.

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Crossref · 10.1111/j.1365-2133.2006.07396.x

Cites

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Citations

Cites

Show all 41 references

Research works printed but not linked: 2

  1. Elder, 1991, Atlas of Tumor Pathology: Melanocytic Tumors of the Skin, 110
  2. Collas, 1999, Evaluation du diagnostic des tumeurs pigmentées de la peau et des èlèments conduisant à un dècision d'exérèse [Evaluation of the diagnosis of pigmented tumors of the skin and factors leading to a decision to excise. Dermatologists of the Postgraduate Association of Haute-Normandie], Ann Dermatol Venerol, 126, 494

Cited by

Metadata

Authors
Bono, A., Tolomio, E., Trincone, S., Bartoli, C., Tomatis, S., Carbone, A., & Santinami, M.
Affiliations
Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
Corresponding author
Bono, A.
ORCID
Venue
British Journal of Dermatology
Publisher
Oxford University Press (OUP)
Published
2006-06-23
Volume
155
Issue
3
Pages
570-573
ISSN
0007-0963 (ISSN-L)
DOI
10.1111/j.1365-2133.2006.07396.x
OpenAlex
W2012960965
Cited by
78
References
41
Citations by year
2026: 3 · 2025: 4 · 2024: 1 · 2023: 1 · 2022: 5 · 2021: 5 · 2020: 6 · 2019: 2 · 2018: 7 · 2017: 6 · 2016: 1 · 2015: 4 · 2014: 3 · 2013: 5 · 2012: 5
FWCI
2.24
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • British Journal of Dermatology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Cutaneous Melanoma Detection and Management
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
  • Health Sciences › Medicine › Dermatology › Cancer and Skin Lesions
Keywords
dermoscopy, diagnosis, sensitivity and specificity, melanoma detection, visual inspection, skin cancer diagnosis
MeSH terms
Adolescent, Adult, Aged, Child, Diagnosis, Differential, Humans, Melanoma, Middle Aged, Nevus, Pigmented, Retrospective Studies, Sensitivity and Specificity, Skin Neoplasms, Dermoscopy

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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