The DOI matches its Crossref record.
Mortality and causes of death in Dutch haemophiliacs, 1973–86
Open accessAbstract
Summary: Mortality figures were calculated for a group of 717 Dutch haemophiliacs over the period 1973‐86. Follow‐up was on average 10.9 years; no patients were lost to follow‐up. The data were compared to the general male population by actuarial methods and patient‐year analysis. Forty‐three patients died, while 20 deaths were expected in a hypothetical group of non‐haemophiliacs of the same age distribution. Hence, overall mortality was 2.1 times higher than in the general population. This leads to a calculated life expectancy of 66 years, as compared to 74 years in the general male population. Mortality did not differ much by severity of haemophilia. A possibly beneficial effect of prophylaxis on longevity was observed. Haemorrhage occurred in half of all deaths and among these traumatic bleeding was the most prevalent. The number of deaths due to ischaemic heart disease was significantly lower (80% reduction) than expected and therefore the authors conclude that haemophilia offers protection against ischaemic heart disease. Cancer mortality was significantly higher (2.5 times) than expected.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Koster, T., Vandenbroucke, J. P., Rosendaal, F. R., Briët, E., Rosendaal, F. R., & Blann, A. D. (1995) · The Lancet · doi:10.1016/s0140-6736(95)90166-3 · Cited by 1,131
Self-citationElevated Factor VIII Levels and the Risk of Thrombosis
Kamphuisen, P. W., Eikenboom, J. C. J., & Bertina, R. M. (2001) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.21.5.731 · Cited by 316
Darby, S. C., Keeling, D. M., Spooner, R. J. D., Wan Kan, S., Giangrande, P. L. F., Collins, P. W., Hill, F. G. H., & Hay, C. R. M. (2004) · Journal of Thrombosis and Haemostasis · doi:10.1046/j.1538-7836.2004.00710.x · Cited by 270
Hemophilia treatment in historical perspective: a review of medical and social developments
Rosendaal, F. R., Smit, C., & Briët, E. (1991) · Annals of Hematology · doi:10.1007/bf01714977 · Cited by 83
Self-citation
Metadata
- Authors
- Rosendaal, F. R., Varekamp, I., Smit, C., Bröcker‐Vriends, A. H. J. T., Van Dijck, H., Vandenbroucke, J. P., Hermans, J., Suurmeijer, T. P. B. M., & Briët, E.
- Venue
- British Journal of Haematology
- Publisher
- Wiley
- Published
- 1989-01
- Volume
- 71
- Issue
- 1
- Pages
- 71-76
- ISSN
- 0007-1048 (ISSN-L)
- 1365-2141
- OpenAlex
- W2044742476
- Cited by
- 205
- References
- 0
- FWCI
- 5.49
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Mortality and causes of death in Dutch haemophiliacs, 1973–86. https://app.cochat.ai/papers/10.1111/j.1365-2141.1989.tb06277.x
- The paper
- Rosendaal, F. R., Varekamp, I., Smit, C., Bröcker‐Vriends, A. H. J. T., Van Dijck, H., Vandenbroucke, J. P., Hermans, J., Suurmeijer, T. P. B. M., & Briët, E. (1989). Mortality and causes of death in Dutch haemophiliacs, 1973–86. British Journal of Haematology. https://doi.org/10.1111/j.1365-2141.1989.tb06277.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
