The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Efficacy of standard dose and 30 ml/kg fresh frozen plasma in correcting laboratory parameters of haemostasis in critically ill patients
Open accessAbstract
Summary: This study assessed the effect on coagulation tests of fresh frozen plasma (FFP), given according to guidelines compared with higher doses in critically ill patients. Group 1 (10 patients) received 12·2 ml/kg and group 2 (12 patients) 33·5 ml/kg FFP. Prothrombin time, activated partial thromboplastin time and factors I–XII were measured before and after FFP infusion. Factor levels of 30 IU/dl (1 g/l for fibrinogen) were considered haemostatic. A retrospective review showed 10 of 22 (five in group 1 and five in group 2) patients had not required FFP. Of those that needed FFP, one of five in group 1 and seven of seven in group 2 had coagulation factor levels above the target post‐FFP. Increments for group 1 versus 2 were: fibrinogen 0·4 vs. 1·0 g/l, FII 16 vs. 41*, FV 10 vs. 28*, FVII 11 vs. 38*, FVIII 10 vs. 17, FIX 8 vs. 28*, FX 15 vs. 37*, FXI 9 vs. 23 and FXII 30 vs. 44 IU/dl* (*P < 0·01). In vivo recovery of coagulation factors was the same for both groups and the observed increments correlated with the dose of FFP. In conclusion, coagulation screens were poor predictors of coagulation factor levels and current guidelines on the use of FFP result in predictably small increments in coagulation factors in critically ill patients and should be reviewed.
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The Risk of Transfusion-Transmitted Viral Infections
Schreiber, G. B., Busch, M. P., Kleinman, S. H., & Korelitz, J. J. (1996) · New England Journal of Medicine · doi:10.1056/nejm199606273342601 · Cited by 1,867
Stehling, L. C., Doherty, D. C., Faust, R. J., Greenburg, A. G., Harrison, C. R., Landers, D. F., Laros, R. K., Pierce, E. C., Prust, R. S., Rosenberg, A. D., et al. (1996) · PubMed · Cited by 894
Makris, M., Greaves, M., Phillips, W. S., Kitchen, S., Rosendaal, F. R., & Preston, F. E. (1997) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1655992 · Cited by 401
Bleeding after liver biopsy does not correlate with indices of peripheral coagulation
Ewe, K. (1981) · Digestive Diseases and Sciences · doi:10.1007/bf01313579 · Cited by 354
Guidelines on oral anticoagulation: third edition
(1998) · British Journal of Haematology · doi:10.1046/j.1365-2141.1998.00715.x · Cited by 314
Ciavarella, D., Reed, R. L., Counts, R. B., Baron, L., Pavlin, E., Heimbach, D. M., & Carrico, C. J. (1987) · British Journal of Haematology · doi:10.1111/j.1365-2141.1987.tb02359.x · Cited by 298
Practice Parameter for the Use of Fresh-Frozen Plasma, Cryoprecipitate, and Platelets
Cooper, E. S. (1994) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1994.03510340067036 · Cited by 295
Youssef, W. (2003) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(03)00241-7 · Cited by 200
Gardiner, S. A. B. M. G. M. D. T. E. E. (2014) · Thrombosis and Haemostasis · doi:10.1160/th · Cited by 148
Cited by
Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology
Kozek-Langenecker, S. A., Afshari, A., Albaladejo, P., Santullano, C. A. A., De Robertis, E., Filipescu, D. C., Fries, D., Görlinger, K., Haas, T., Imberger, G., et al. (2013) · European Journal of Anaesthesiology · doi:10.1097/eja.0b013e32835f4d5b · Cited by 909
Prevention and Management of Postpartum Haemorrhage: Green‐top Guideline No. 52
(2017) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.14178 · Cited by 756
Frontera, J. A., Lewin III, J. J., Rabinstein, A. A., Aisiku, I. P., Alexandrov, A. W., Cook, A. M., del Zoppo, G. J., Kumar, M. A., Peerschke, E. I. B., Stiefel, M. F., et al. (2016) · Neurocritical Care · doi:10.1007/s12028-015-0222-x · Cited by 706
Schöchl, H., Nienaber, U., Maegele, M., Hochleitner, G., Primavesi, F., Steitz, B., Arndt, C., Hanke, A., Voelckel, W., & Solomon, C. (2011) · Critical Care · doi:10.1186/cc10078 · Cited by 398
Blood Coagulation: Hemostasis and Thrombin Regulation
Tanaka, K. A., Key, N. S., & Levy, J. H. (2009) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e31819bcc9c · Cited by 342
Metadata
- Authors
- Chowdhury, P., Saayman, A. G., Paulus, U., Findlay, G. P., & Collins, P. W.
- Venue
- British Journal of Haematology
- Publisher
- Wiley
- Published
- 2004-02-27
- Volume
- 125
- Issue
- 1
- Pages
- 69-73
- ISSN
- 0007-1048 (ISSN-L)
- 1365-2141
- OpenAlex
- W2042603596
- Cited by
- 381
- References
- 10
- FWCI
- 14.84
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Chowdhury, P., Saayman, A. G., Paulus, U., Findlay, G. P., & Collins, P. W. (2004). Efficacy of standard dose and 30 ml/kg fresh frozen plasma in correcting laboratory parameters of haemostasis in critically ill patients. British Journal of Haematology. https://doi.org/10.1111/j.1365-2141.2004.04868.x
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