The DOI matches its Crossref record; 241 of the 242 references it cites were found in a registry or an index.
The sick euthyroid syndrome: changes in thyroid hormone serum parameters and hormone metabolism
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In the citing paper
“While serum T3 levels may decline by 30%, which is significant, but still within the so-called “normal range”, tissue T3 may decline by 70–80%, resulting in profound cellular hypothyroidism with normal serum TSH, FT4, and FT3 levels”
From Diagnosis and management of treatment-refractory hypothyroidism: an expert consensus report (2017) · cites this paper as [31]
In the citing paper
“As a result, TSH may be a poor indicator of peripheral thyroid levels in the presence of such conditions.”
From Diagnosis and management of treatment-refractory hypothyroidism: an expert consensus report (2017) · cites this paper as [31]
Citations
Cites
Items 201–241 of 241
Effects of immunoscintigraphy with monoclonal antibodies in assays of hormones and tumour markers.
Janssen, J. A. M. J. L., Blankestijn, P. J., Docter, R., BLIJENBERG, B. G., Splinter, T. A. W., van Toor, H., Schalekamp, M. A. D. H., Lamberts, S. W. J., & Krenning, E. P. (1989) · BMJ · doi:10.1136/bmj.298.6686.1511 · Cited by 18
Self-citationTHYROXINE ANALOGUE ASSAY KITS IN CLINICAL MEDICINE
Wenzel, K. W., Ekins, R. P., & Jackson, T. (1985) · The Lancet · doi:10.1016/s0140-6736(85)90662-2 · Cited by 17
EFFECTS OF CHRONIC RENAL DISEASE ON THYROID HORMONE METABOLISM
Finucane, J., Griffiths, R., Black, E. G., & Hall, C. L. (1977) · European Journal of Endocrinology · doi:10.1530/acta.0.0840750 · Cited by 17
Csákó, G., ZWEIG, M. H., Ruddel, M. E., Glickman, J., & Kestner, J. (1990) · Clinical Chemistry · doi:10.1093/clinchem/36.4.645 · Cited by 16
Hintze, G., Braverman, L. E., & Ingbar, S. H. (1991) · Endocrinology · doi:10.1210/endo-128-1-146 · Cited by 16
Kubasik, N. P., Lundberg, P. A., Brodows, R. G., Hallauer, G. D., G, D., Lindstedt, G., Bengtsson, C., & Nyström, E. (1983) · Clinical Chemistry · doi:10.1093/clinchem/29.10.1781 · Cited by 15
Docter, R., de Jong, M., van der Hoek, H. J., Krenning, E. P., & HENNEMANN, G. (1990) · Endocrinology · doi:10.1210/endo-126-1-451 · Cited by 15
Self-citationRodrı́guez-Espinosa, J., Ordóñez‐Llanos, J., Gómez-Gerique, J. A., & Móra, J. (1984) · Clinical Chemistry · doi:10.1093/clinchem/30.1.151 · Cited by 15
Evaluation of Five High-Sensitivity American Thyrotropin Assays
Hershman, J. M., Pekary, A. E., SMITH, V. P., & Hershman, J. D. (1988) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)65510-4 · Cited by 14
THYROID-STIMULATING HORMONE MEASUREMENTS BY IMMUNORADIOMETRIC ASSAY IN SEVERELY ILL PATIENTS
Dubuis, J.-M., & Burger, A. (1986) · The Lancet · doi:10.1016/s0140-6736(86)92641-3 · Cited by 14
Midgley, J. E. M., & Wilkins, T. A. (1983) · Clinical Chemistry · doi:10.1093/clinchem/29.10.1861 · Cited by 14
Etienne-Decerf, J., Gosselin-Rey, C., Gosselin, L., & WINAND, R. J. (1986) · Journal of Endocrinological Investigation · doi:10.1007/bf03348065 · Cited by 13
Nicolson, R., Reilly, C. P., Pannall, P. R., Esposito, L. M., & WELLBY, M. L. (1989) · Clinical Chemistry · doi:10.1093/clinchem/35.6.931 · Cited by 12
Evaluation of free thyroxin measurements in patients with non-thyroidal illnesses.
Lawlor, J., & Blaustein, M. P. (1981) · Clinical Chemistry · doi:10.1093/clinchem/27.8.1457 · Cited by 12
A two-step radioimmunoassay for free triiodothyronine in serum.
Rajan, M. G. R., & Samuel, A. M. (1987) · Clinical Chemistry · doi:10.1093/clinchem/33.3.372 · Cited by 12
Wang, Y.-S., Pekary, A. E., England, M. L., & Hershman, J. M. (1985) · Journal of Endocrinological Investigation · doi:10.1007/bf03348546 · Cited by 12
Concentration of free thyroxin in serum during nonthyroidal illness--calculation or measurement?
Konno, N., Hirokawa, J., Tsuji, M., Hagiwara, K., Taguchi, H., Murakami, S., & Taguchi, S. (1989) · Clinical Chemistry · doi:10.1093/clinchem/35.1.159 · Cited by 11
Braverman, L. E. (1967) · JAMA · doi:10.1001/jama.1967.03120070081011 · Cited by 11
ACCUMULATION AND RELEASE OF THYROID HORMONES BY THE NORMAL AND DISEASED HUMAN LIVER
Zaninovich, Á. A., Volpe, R. J., Soto, R. J., & EZRIN, C. (1969) · European Journal of Endocrinology · doi:10.1530/acta.0.0600412 · Cited by 11
Thyroid function in hospitalized patients: effect of illness and serum albumin concentrations.
Desai, R. K., Jialal, I., Aitchison, J., & Joubert, S. M. (1987) · Clinical Chemistry · doi:10.1093/clinchem/33.8.1445 · Cited by 11
Ehrmann, D. A. (1989) · Archives of Internal Medicine · doi:10.1001/archinte.149.2.369 · Cited by 11
(1986) · Clinical Chemistry · doi:10.1093/clinchem/32.3.565 · Cited by 11
The charcoal T3 ratio. An in vitro test of thyroid function
Braverman, L. E. (1967) · JAMA · doi:10.1001/jama.199.7.469 · Cited by 10
Roosdorp, N., & Joustra, M. (1979) · Clinica Chimica Acta · doi:10.1016/0009-8981(79)90161-x · Cited by 9
Assessment of an Enhanced Chemiluminescent Immunometric Assay for TSH in 1127 Patients
Squire, C. R., & Gimlette, T. M. D. (1987) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/000456328702400412 · Cited by 9
Moser, R. J., & Hollingsworth, D. R. (1975) · Clinical Chemistry · doi:10.1093/clinchem/21.3.347 · Cited by 8
One-step immunoassays for free (unbound) hormones: the effect of tracer binding by serum proteins.
Geiseler, D., Chodha, P., & Ekins, R. P. (1986) · Clinical Chemistry · doi:10.1093/clinchem/32.1.45 · Cited by 8
Waud, J. M., Chan, D. W., Drew, H. M., Oropeza, M., Sucupira, M. S., Scheinin, B., Garrison, G. M., Mayo, M., Taylor, E., & Stem, J. (1983) · Clinical Chemistry · doi:10.1093/clinchem/29.11.1908 · Cited by 7
Thyroid Hormone Binding Inhibition in Critically ill Patients – Who is the Inhibitor?
Schifferdecker, E., Hering, S., Böhm, B. O., Förster, H., Althoff, P.-H., Schulz, F., & Schöffling, K. (2009) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1210963 · Cited by 7
Liewendahl, K., Mähönen, H., Tikanoja, S., Helenius, T., Turula, M., & Välimäki, M. J. (1986) · Clinical Chemistry · doi:10.1093/clinchem/32.12.2209a · Cited by 7
Diagnostic value of a modified assay of free triiodothyronine in serum.
Forshaw, K. M., & van Heyningen, C. (1987) · Clinical Chemistry · doi:10.1093/clinchem/33.11.2093 · Cited by 7
Three-compartmental analysis of effects of D-propranolol on thyroid hormone kinetics
van der Heijden, J. T., Krenning, E. P., van Toor, H., Hennemann, G., & Docter, R. (1988) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1988.255.1.e80 · Cited by 6
Self-citationClinical assessment of a radioimmunoassay for free thyroxine using a modified tracer.
Chan, D. W., Waud, J. M., & Hsu, T. H. (1983) · PubMed · Cited by 6
Estimation of free thyroxin with a new thyroxin analog and a porous-glass solid phase.
Witherspoon, L. R., Shuler, S. E., & Gilbert, S. (1984) · Clinical Chemistry · doi:10.1093/clinchem/30.5.778 · Cited by 6
Abnormal Thyroid Function Tests in Euthyroid Patients
DeGroot, L. J. (1989) · Springer eBooks · doi:10.1007/978-1-4612-3612-2_1 · Cited by 5
Maberly, G., Waite, K., Ma, G., Soni, N., & Eastman, C. J. (1986) · Clinical Chemistry · doi:10.1093/clinchem/32.4.616 · Cited by 5
Krenning, E. P., Docter, R., van Toor, H., Ac, P., Postema, P. T., Visser, T. J., & HENNEMANN, G. (1986) · PubMed · Cited by 4
Self-citationAnalytical evaluation of twenty assays for determination of thyrotropin (TSH).
Jc, L., Simonet, L., & Gillet, R. (1989) · PubMed · Cited by 4
Enzyme immunoassay of free triiodothyronine in serum.
Hata, N., Miyai, K., Endo, Y., Iijima, Y., Doi, Y., Amino, N., & Ichihara, K. (1987) · Clinical Chemistry · doi:10.1093/clinchem/33.1.172 · Cited by 4
Oberkotter, L. V., FARMER, L. C., & Farber, M. (1985) · Endocrinology · doi:10.1210/endo-117-2-511 · Cited by 3
Analytical and Clinical Evaluation of Three Sensitive Thyrotropin Assays
Bonte, H. A., Vermes, I., & Veer, G. V. D. S. (1989) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/000456328902600609 · Cited by 3
Flagged first, then by citations
1 of the 242 references couldn’t be matched to a known paper.
Research works printed but not linked: 24
- 10.1210/en.131.1.463 · DOI
- Docter R., 1990, The Thyroid Gland, 233
- Hennemann G., 1990, The Thyroid Gland, 221
- Kaptein E.M., 1986, Thyroid Hormone Metabolism, 297
- Kirkegaard C., 1985, Thyroid test strategy, Lancet, 1455
- Krenning E.P., 1987, “Modern” evaluation of thyroid function, Progressi in Medicina di Laboratorio, 1, 237
- Leonard J.L., 1990, The Thyroid Gland, 285
- Leonard J.L., 1986, Thyroid Hormone Metabolism, 189
- Lim C‐F., 1991, Progress in Thyroid Research, 709
- Lim C‐F., 1991, Inhibition of thyroid hormone metabolism in non‐thyroidal illness (NTI): Possible roles of a furanic acid, hippuric acid (HA), and indoxyl sulfate (IS), Annates ďEndocrinologie, 52, 71
- Lim C‐F., 1992, Four inhibitors of liver T4 uptake in non‐thyroidal illness, Thyroid, 2, S‐87
- Lim C‐F., 1992, Bilirubin and non‐esterified fatty acids (NEFA) are the inhibitors of T4 metabolism in critical illness, Journal of Endocrinological Investigation, 15, 46
- 10.1210/jc.76.5.1165 · DOI
- 10.1210/jc.76.2.318 · DOI
- Mariotti S., 1990, The Thyroid Gland, 147
- Montoro M., 1981, Adult thyroid screening in hospitalized patients, Clinical Research, 29, 39A
- Spencer C.A., 1985, The comparative clinical value of free T4 estimation using different methodological approaches, Nuc Compact, 16, 321
- Spencer C.A., 1986, Clinical evaluation of free T4 techniques, Journal of Endocrinological Investigation, 9, 57
- Spencer C.A., 1989, Thyroid profiling for the 1990s: Free T4 estimate or sensitive TSH measurement, Journal of Clinical Immunoassay, 12, 82
- Vagenakis A.G., 1981, The Low T3 Syndrome, 128
- Heyden J.T.M., 1986, Effect of caloric deprivation on the thyroid hormone tissue uptake and the generation of low‐T3 syndrome, American Journal of Physiology, 251, E156
- Visser T.J., 1990, The Thyroid Gland, 255
- Vos R., 1991, Progress in Thyroid Research, 693
- Vos R., 1991, Progress in Thyroid Research, 717
Cited by
Sorted by citations
Jonklaas, J., Bianco, A. C., Bauer, A. J., Burman, K. D., Cappola, A. R., Celi, F. S., Cooper, D. S., Kim, B. W., Peeters, R. P., Rosenthal, M. S., et al. (2014) · Thyroid® · doi:10.1089/thy.2014.0028 · Cited by 1,928
“A minority view holds that the changes seen, while perhaps a common pathway, are nonetheless pathologic (623,624).”
Bianco, A. C., Salvatore, D., Gereben, B., Berry, M. J., & Larsen, P. R. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.1.0455 · Cited by 1,853
Pathophysiologic Response to Severe Burn Injury
Jeschke, M. G., Chinkes, D. L., Finnerty, C. C., Kulp, G. A., Suman-Vejas, O. E., Norbury, W. B., Branski, L. K., Gauglitz, G. G., Mlcak, R. P., & Herndon, D. N. (2008) · Annals of Surgery · doi:10.1097/sla.0b013e3181856241 · Cited by 719
Légrádi, G., Emerson, C. H., Ahima, R. S., Flier, J. S., & Lechan, R. M. (1997) · Endocrinology · doi:10.1210/en.138.6.2569 · Cited by 505
Dangerous dogmas in medicine: the nonthyroidal illness syndrome
De Groot, L. J. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.1.5364 · Cited by 505
Metadata
- Authors
- Docter, R., Krenning, E. P., de Jong, M., & Hennemann, G.
- Affiliations
- Erasmus MC (NL)
- Corresponding author
- Docter, R.
- ORCID
- Krenning, E. P.
- Venue
- Clinical Endocrinology
- Publisher
- Wiley
- Published
- 1993-11
- Volume
- 39
- Issue
- 5
- Pages
- 499-518
- ISSN
- 0300-0664 (ISSN-L)
- 1365-2265
- OpenAlex
- W2121588417
- Cited by
- 345
- References
- 242
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 4 · 2023: 7 · 2022: 12 · 2021: 6 · 2020: 8 · 2019: 12 · 2018: 6 · 2017: 6 · 2016: 10 · 2015: 10 · 2014: 9 · 2013: 12 · 2012: 10
- FWCI
- 3.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
- Keywords
- low T3 syndrome, thyroid hormones, serum thyroid hormones, thyroid hormone metabolism
- MeSH terms
- Euthyroid Sick Syndromes, Humans, Thyroid Hormones, Thyrotropin, Thyroxine, Triiodothyronine
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