The DOI matches its Crossref record.
Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Another important consideration is that patients with severe CP often have compounding risk factors, including decreased muscle mass, impaired shivering response, limited voluntary control of clothing/environment, PEG dependence and malnutrition, reducing metabolic heat production, and chronic antiepileptic therapy modulating CNS neurotransmitters involved in temperature regulation [7-10].”
From Recurrent Severe Hypothermia as a Manifestation of Central Thermoregulatory Dysfunction in a Patient With Cerebral Palsy and Shaken Baby Syndrome (2026) · cites this paper as [10]
In the citing paper
“Another important consideration is that patients with severe CP often have compounding risk factors, including decreased muscle mass, impaired shivering response, limited voluntary control of clothing/environment, PEG dependence and malnutrition, reducing metabolic heat production, and chronic antiepileptic therapy modulating CNS neurotransmitters involved in temperature regulation [7-10].”
From Recurrent Severe Hypothermia as a Manifestation of Central Thermoregulatory Dysfunction in a Patient With Cerebral Palsy and Shaken Baby Syndrome (2026) · cites this paper as [10]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 19
- Danzl, 2002, Hypothermia, Seminars in Respiratory and Critical Care Medicine, 23, 57, 10.1055/s-2002-20589 · DOI
- Tanelian, 1993, The role of the GABAA receptor/chloride channel complex in anesthesia, Anesthesiology, 78, 757, 10.1097/00000542-199304000-00020 · DOI · Paper page
- Jurd, 2003, General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit, FASEB Journal, 17, 250, 10.1096/fj.02-0611fje · DOI · Paper page
- Dodgson, 2000, Topiramate as an inhibitor of carbonic anhydrase isoenzymes, Epilepsia, 41, S35, 10.1111/j.1528-1157.2000.tb06047.x · DOI · Paper page
- Nishimori, 2005, Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors, Journal of Medicinal Chemistry, 48, 7860, 10.1021/jm050483n · DOI
- White, 1997, Topiramate enhances GABA-mediated chloride influx and GABA-evoked currents in mouse brain neurons and increases seizure threshold, Epilepsy Research, 28, 167, 10.1016/S0920-1211(97)00045-4 · DOI · Paper page
- Szarfman, 2002, Use of screening algorithms and computer systems to efficiently signal higher-than-expected combinations of drugs and events in the US FDA’s spontaneous reports database, Drug Safety, 25, 381, 10.2165/00002018-200225060-00001 · DOI · Paper page
- Longin, 2002, Topiramate enhances the risk of valproate-associated side effects in three children, Epilepsia, 43, 451, 10.1046/j.1528-1157.2002.42401.x · DOI
- Wegerer, 2005, Recurrent prolonged impairment of consciousness and hypothermia due to valproate treatment in a female patient with severe mental retardation, Epilepsia, 46, 44
- Stowe, 2000, Acute mental changes and hyperchloremic metabolic acidosis with long term topiramate therapy, Pharmacotherapy, 20, 105, 10.1592/phco.20.1.105.34662 · DOI
- Zachariah, 2000, Hypothermia and thermoregulatory derangements induced by valproic acid, Neurology, 55, 150, 10.1212/WNL.55.1.150 · DOI
- Kempainen, 2004, The evaluation and management of accidental hypothermia, Respiratory Care, 49, 192
- Blass, 2004, Olanzapine-associated hypothermia, Psychosomatics, 45, 135, 10.1176/appi.psy.45.2.135 · DOI
- Young, 1996, Risk factors for hypothermia in psychiatric patients, Annals of Clinical Psychiatry, 8, 93, 10.3109/10401239609148807 · DOI
- Jackson, 1959, Hypothermia IV. Study of hypothermia induction time with various pharmacological agents, Proceedings of the Society for Experimental Biology and Medicine, 100, 332, 10.3181/00379727-100-24617 · DOI
- Zeng, 2000, Role of bicarbonate ion in mediating decreased synaptic conductance in benzodiazepine tolerant hippocampal CA1 pyramidal neurons, Brain Research, 868, 202, 10.1016/S0006-8993(00)02330-1 · DOI
- Pasternak, 1992, Influence of extracellular and intracellular pH on GABA-gated chloride conductance in crayfish muscle fibers, Neuroscience, 47, 921, 10.1016/0306-4522(92)90040-9 · DOI
- Huang, 2004, Molecular basis for modulation of recombinant α1β2 γ2 GABAA receptors by protons, Journal of Neurophysiology, 92, 883, 10.1152/jn.01040.2003 · DOI
- Pasternack, 1996, Proton modulation of functionally distinct GABAA receptors in acutely isolated pyramidal neurons of rat hippocampus, Neuropharmacology, 35, 1279, 10.1016/S0028-3908(96)00075-5 · DOI
Cited by
Allnutt, B., Petrasko, P., & Jacob, R. (2026) · Cureus · doi:10.7759/cureus.102330
Metadata
- Authors
- Knudsen, J. F., Sokol, G. H., & Flowers, C. M.
- Venue
- Journal of Clinical Pharmacy and Therapeutics
- Publisher
- Hindawi Limited
- Published
- 2008-10
- Volume
- 33
- Issue
- 5
- Pages
- 513-519
- ISSN
- 0269-4727
- 1365-2710
- Cited by
- 30
- References
- 0
- Language
- en
- Licence
- doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 2526 d)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy. https://app.cochat.ai/papers/10.1111/j.1365-2710.2008.00943.x
- The paper
- Knudsen, J. F., Sokol, G. H., & Flowers, C. M. (2008). Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy. Journal of Clinical Pharmacy and Therapeutics. https://doi.org/10.1111/j.1365-2710.2008.00943.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
