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Cited by 356

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Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2)

Jiang, X.‐M., Neal, B., Santiago, F., Lee, S. J., Romana, L. K., Reeves, P. R.·1991·Molecular Microbiology

Abstract

Summary: The rfb gene cluster of Salmonella LT2 has been cloned and sequenced. The genes rfbA, rfbB, rfbD, rfbF, rfbG, rfbK, rfbM and rfbP were located individually and the gene rfbL was located outside the cluster. Approximately 16 open reading frames were found in the region which is essential for the expression of O antigen. The gene products of rfbB and rfbG were found to have homology with the group of dehydrogenase and related enzymes described previously. Analysis of the G+C ratio of the rfb cluster extended the area of low‐G+C composition previously found in the sequence of rfbJ to the whole rfb gene cluster. Three to five segments with discrete G+C contents and codon adaptation indices are present in the rfb region, indicating a heterogeneous origin of these segments. Potential promoters were found near the start of the rfb region, supporting the possibility that the rfb gene cluster is an operon.

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Crossref · 10.1111/j.1365-2958.1991.tb00741.x

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Metadata

Authors
Jiang, X. ‐., Neal, B., Santiago, F., Lee, S. J., Romana, L. K., & Reeves, P. R.
Venue
Molecular Microbiology
Publisher
Wiley
Published
1991-03
Volume
5
Issue
3
Pages
695-713
ISSN
  • 0950-382X (ISSN-L)
  • 1365-2958
OpenAlex
W2131891756
Cited by
356
References
1
FWCI
21.09
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2). https://app.cochat.ai/papers/10.1111/j.1365-2958.1991.tb00741.x
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Jiang, X. ‐., Neal, B., Santiago, F., Lee, S. J., Romana, L. K., & Reeves, P. R. (1991). Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2). Molecular Microbiology. https://doi.org/10.1111/j.1365-2958.1991.tb00741.x

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