The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Sex and virulence in Escherichia coli: an evolutionary perspective
Open accessAbstract
Summary: Pathogenic Escherichia coli cause over 160 million cases of dysentery and one million deaths per year, whereas non‐pathogenic E. coli constitute part of the normal intestinal flora of healthy mammals and birds. The evolutionary pathways underlying this dichotomy in bacterial lifestyle were investigated by multilocus sequence typing of a global collection of isolates. Specific pathogen types [enterohaemorrhagic E. coli, enteropathogenic E. coli, enteroinvasive E. coli, K1 and Shigella] have arisen independently and repeatedly in several lineages, whereas other lineages contain only few pathogens. Rates of evolution have accelerated in pathogenic lineages, culminating in highly virulent organisms whose genomic contents are altered frequently by increased rates of homologous recombination; thus, the evolution of virulence is linked to bacterial sex. This long‐term pattern of evolution was observed in genes distributed throughout the genome, and thereby is the likely result of episodic selection for strains that can escape the host immune response.
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Cites
Multiple Comparisons of Log-Likelihoods with Applications to Phylogenetic Inference
Shimodaira, H., & Hasegawa, M. (1999) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a026201 · Cited by 4,237
The population genetics of ecological specialization in evolving Escherichia coli populations
Cooper, V. S., & Lenski, R. E. (2000) · Nature · doi:10.1038/35037572 · Cited by 519 · cited 4×
“coli have been detected in laboratory experiments (Sniegowski et al ., 1997; Vulic et al ., 1999; Cooper and Lenski, 2000) and among natural isolates (Denamur et al .”
BackgroundInfluential
Cited by
An ecological and evolutionary perspective on human–microbe mutualism and disease
Dethlefsen, L., McFall-Ngai, M., & Relman, D. A. (2007) · Nature · doi:10.1038/nature06245 · Cited by 1,660
(2019) · doi:10.1101/gr.251678.119 · Cited by 976
The microbiome of uncontacted Amerindians
Clemente, J. C., Pehrsson, E. C., Blaser, M. J., Sandhu, K., Gao, Z., Wang, B., Magris, M., Hidalgo, G., Contreras, M., Noya-Alarcón, Ó., et al. (2015) · Science Advances · doi:10.1126/sciadv.1500183 · Cited by 851
Multilocus sequence typing as a replacement for serotyping in Salmonella enterica
Achtman, M., Wain, J., Weill, F.-X., Nair, S., Zhou, Z., Sangal, V., Krauland, M. G., Hale, J. L., Harbottle, H., Uesbeck, A., et al. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002776 · Cited by 710
Self-citationPattern pluralism and the Tree of Life hypothesis
Doolittle, W. F., & Bapteste, E. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610699104 · Cited by 546
Metadata
- Authors
- Wirth, T., Falush, D., Lan, R., Colles, F., Mensa, P., Wieler, L. H., Karch, H., Reeves, P. R., Maiden, M. C. J., Ochman, H., & Achtman, M.
- Venue
- Molecular Microbiology
- Publisher
- Wiley
- Published
- 2006-05-04
- Volume
- 60
- Issue
- 5
- Pages
- 1136-1151
- ISSN
- 0950-382X (ISSN-L)
- 1365-2958
- OpenAlex
- W2161060487
- Cited by
- 2,025
- References
- 2
- FWCI
- 30.20
- Type
- journal article
- Language
- en
- Open access
- green
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- Wirth, T., Falush, D., Lan, R., Colles, F., Mensa, P., Wieler, L. H., Karch, H., Reeves, P. R., Maiden, M. C. J., Ochman, H., & Achtman, M. (2006). Sex and virulence in Escherichia coli: an evolutionary perspective. Molecular Microbiology. https://doi.org/10.1111/j.1365-2958.2006.05172.x
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