The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Negative regulation of defense responses in Arabidopsis by two NPR1 paralogs
Open accessAbstract
Summary: NPR1 is required for systemic acquired resistance, and there are five NPR1 paralogs in Arabidopsis. Here we report knockout analysis of two of these, NPR3 and NPR4. npr3 single mutants have elevated basal PR‐1 expression and the npr3 npr4 double mutant shows even higher expression. The double mutant plants also display enhanced resistance against virulent bacterial and oomycete pathogens. This enhanced disease resistance is partially dependent on NPR1, can be in part complemented by either wild‐type NPR3 or NPR4, and is not associated with an elevated level of salicylic acid. NPR3 and NPR4 interact with TGA2, TGA3, TGA5 and TGA6 in yeast two‐hybrid assays. Using bimolecular fluorescence complementation analysis, we show that NPR3 interacts with TGA2 in the nucleus of onion epidermal cells and Arabidopsis mesophyll protoplasts. Combined with our previous finding that basal PR‐1 levels are also elevated in the tga2 tga5 tga6 triple mutant, we propose that NPR3 and NPR4 negatively regulate PR gene expression and pathogen resistance through their association with TGA2 and its paralogs.
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Citations
Cites
BLADE-ON-PETIOLE–Dependent Signaling Controls Leaf and Floral Patterning in Arabidopsis
Hepworth, S. R., Zhang, Y., McKim, S., Li, X., & Haughn, G. W. (2005) · The Plant Cell · doi:10.1105/tpc.104.030536 · Cited by 351 · cited 3×
“BOP1 and BOP2 interact with PERIANTHIA (AtbZip46), a bZip transcription factor in the TGA subfamily (Hepworth et al., 2005).”
BackgroundSelf-citationThe BLADE ON PETIOLE genes act redundantly to control the growth and development of lateral organs
Norberg, M., Holmlund, M., & Nilsson, O. (2005) · Development · doi:10.1242/dev.01815 · Cited by 245
Cited by
Systemic Acquired Resistance: Turning Local Infection into Global Defense
Fu, Z. Q., & Dong, X. (2013) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105606 · Cited by 1,524
Salicylic acid beyond defence: its role in plant growth and development
Rivas-San Vicente, M., & Plasencia, J. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/err031 · Cited by 1,444
The Plant Vascular System: Evolution, Development and Functions F
Lucas, W. J., Groover, A., Lichtenberger, R., Furuta, K., Yadav, S., Helariutta, Y., He, X., Fukuda, H., Kang, J., Brady, S. M., et al. (2013) · Journal of Integrative Plant Biology · doi:10.1111/jipb.12041 · Cited by 772
Argout, X., Salse, J., Aury, J.-M., Guiltinan, M. J., Droc, G., Gouzy, J., Allegre, M., Chaparro, C., Legavre, T., Maximova, S. N., et al. (2011) · Nature Genetics · doi:10.1038/ng.736 · Cited by 746
Self-citationSalicylic Acid: Biosynthesis and Signaling
Peng, Y., Yang, J., Li, X., & Zhang, Y. (2021) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-081320-092855 · Cited by 560
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Metadata
- Authors
- Zhang, Y., Cheng, Y. T., Qu, N., Zhao, Q., Bi, D., & Li, X.
- Venue
- The Plant Journal
- Publisher
- Wiley
- Published
- 2006-10-31
- Volume
- 48
- Issue
- 5
- Pages
- 647-656
- ISSN
- 0960-7412 (ISSN-L)
- 1365-313X
- OpenAlex
- W2126302335
- Cited by
- 271
- References
- 2
- FWCI
- 6.58
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Zhang, Y., Cheng, Y. T., Qu, N., Zhao, Q., Bi, D., & Li, X. (2006). Negative regulation of defense responses in Arabidopsis by two NPR1 paralogs. The Plant Journal. https://doi.org/10.1111/j.1365-313x.2006.02903.x
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