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Will disruptive mood dysregulation disorder reduce false diagnosis of bipolar disorder in children?
Abstract
Objectives The frequency of diagnosis of bipolar disorder has risen dramatically in children and adolescents. The DSM-V Work Group has suggested a new diagnosis termed disruptive mood dysregulation disorder (DMDD) (formerly temper dysregulation disorder with dysphoria) to reduce the rate of false diagnosis of bipolar disorder in young people. We sought to determine if the application of the proposed diagnostic criteria for DMDD would reduce the rate of diagnosis of bipolar disorder in children. Patients and methods Eighty-two consecutively hospitalized children, ages 5 to 12 years, on a children's inpatient unit were rigorously diagnosed using admission interviews of the parents and the child, rating scales, and observation over the course of hospitalization. Results Overall, 30.5% of inpatient children met criteria for DMDD by parent report, and 15.9% by inpatient unit observation. Fifty-six percent of inpatient children had parent-reported manic symptoms. Of those, 45.7% met criteria for DMDD by parent-report, though only 17.4% did when observed on the inpatient unit. Conclusion Although DMDD does decrease the rate of diagnosis of bipolar disorder in children, how much depends on whether history or observation is used.
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DMDD was added to the DSM-5 to provide a prominent diagnostic 'home' for children who were being misdiagnosed as having bipolar disorder and were therefore receiving inappropriate treatments such as antipsychotics and mood stabilizers.
“DMDD was added to the DSM-5 to provide a prominent diagnostic 'home' for children who were being misdiagnosed as having bipolar disorder and were therefore receiving inappropriate treatments such as antipsychotics and mood stabilizers 31,77 .”
From An organization‐ and category‐level comparison of diagnostic requirements for mental disorders in ICD ‐11 and DSM ‐5 (2021) · cites this paper as [77]
Studies in clinical and community samples have found that 70-100% of children with DMDD have symptoms that meet the diagnostic requirements for ODD.
“Studies in clinical and community samples have found that 70-100% of children with DMDD have symptoms that meet the diagnostic requirements for ODD 77,79-82 , suggesting that the irritability and behavioural symptom dimensions of ODD are not separable into different disorders 31,78 .”
From An organization‐ and category‐level comparison of diagnostic requirements for mental disorders in ICD ‐11 and DSM ‐5 (2021) · cites this paper as [77]
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Metadata
- Authors
- Margulies, D. M., Weintraub, S., Basile, J., Grover, P. J., & Carlson, G. A.
- Affiliations
- State University of New York (US)
- Stony Brook University Hospital (US)
- Corresponding author
- Carlson, Gabrielle A
- Venue
- Bipolar Disorders
- Publisher
- Wiley
- Published
- 2012-06-19
- Volume
- 14
- Issue
- 5
- Pages
- 488-496
- ISSN
- 1398-5647 (ISSN-L)
- 1399-5618
- OpenAlex
- W1528781873
- Cited by
- 104
- References
- 39
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 15 · 2023: 2 · 2022: 1 · 2021: 7 · 2020: 7 · 2019: 10 · 2018: 8 · 2017: 9 · 2016: 19 · 2015: 7 · 2014: 7 · 2013: 6 · 2012: 1
- FWCI
- 4.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Bipolar Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- disruptive mood dysregulation disorder, bipolar disorder, false diagnosis, children, adolescents, diagnostic criteria, DSM-5, manic symptoms, parent report, hospitalized children
- MeSH terms
- Aggression, Bipolar Disorder, Child, Child, Preschool, Diagnostic Errors, Female, Humans, Inpatients, Male, Psychiatric Status Rating Scales, Mood Disorders, Diagnostic and Statistical Manual of Mental Disorders
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