Cited by 104Bipolar Disorder and TreatmentChild and Adolescent Psychosocial and Emotional DevelopmentPersonality Disorders and Psychopathology

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Will disruptive mood dysregulation disorder reduce false diagnosis of bipolar disorder in children?

Abstract

Objectives The frequency of diagnosis of bipolar disorder has risen dramatically in children and adolescents. The DSM-V Work Group has suggested a new diagnosis termed disruptive mood dysregulation disorder (DMDD) (formerly temper dysregulation disorder with dysphoria) to reduce the rate of false diagnosis of bipolar disorder in young people. We sought to determine if the application of the proposed diagnostic criteria for DMDD would reduce the rate of diagnosis of bipolar disorder in children. Patients and methods Eighty-two consecutively hospitalized children, ages 5 to 12 years, on a children's inpatient unit were rigorously diagnosed using admission interviews of the parents and the child, rating scales, and observation over the course of hospitalization. Results Overall, 30.5% of inpatient children met criteria for DMDD by parent report, and 15.9% by inpatient unit observation. Fifty-six percent of inpatient children had parent-reported manic symptoms. Of those, 45.7% met criteria for DMDD by parent-report, though only 17.4% did when observed on the inpatient unit. Conclusion Although DMDD does decrease the rate of diagnosis of bipolar disorder in children, how much depends on whether history or observation is used.

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  • DMDD was added to the DSM-5 to provide a prominent diagnostic 'home' for children who were being misdiagnosed as having bipolar disorder and were therefore receiving inappropriate treatments such as antipsychotics and mood stabilizers.

    “DMDD was added to the DSM-5 to provide a prominent diagnostic 'home' for children who were being misdiagnosed as having bipolar disorder and were therefore receiving inappropriate treatments such as antipsychotics and mood stabilizers 31,77 .”
  • Studies in clinical and community samples have found that 70-100% of children with DMDD have symptoms that meet the diagnostic requirements for ODD.

    “Studies in clinical and community samples have found that 70-100% of children with DMDD have symptoms that meet the diagnostic requirements for ODD 77,79-82 , suggesting that the irritability and behavioural symptom dimensions of ODD are not separable into different disorders 31,78 .”

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Metadata

Authors
Margulies, D. M., Weintraub, S., Basile, J., Grover, P. J., & Carlson, G. A.
Affiliations
  • State University of New York (US)
  • Stony Brook University Hospital (US)
Corresponding author
Carlson, Gabrielle A
Venue
Bipolar Disorders
Publisher
Wiley
Published
2012-06-19
Volume
14
Issue
5
Pages
488-496
ISSN
  • 1398-5647 (ISSN-L)
  • 1399-5618
OpenAlex
W1528781873
Cited by
104
References
39
Citations by year
2026: 2 · 2025: 3 · 2024: 15 · 2023: 2 · 2022: 1 · 2021: 7 · 2020: 7 · 2019: 10 · 2018: 8 · 2017: 9 · 2016: 19 · 2015: 7 · 2014: 7 · 2013: 6 · 2012: 1
FWCI
4.77
Type
journal article
Language
en
Open access
closed
Locations
  • Bipolar Disorders (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords
disruptive mood dysregulation disorder, bipolar disorder, false diagnosis, children, adolescents, diagnostic criteria, DSM-5, manic symptoms, parent report, hospitalized children
MeSH terms
Aggression, Bipolar Disorder, Child, Child, Preschool, Diagnostic Errors, Female, Humans, Inpatients, Male, Psychiatric Status Rating Scales, Mood Disorders, Diagnostic and Statistical Manual of Mental Disorders

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