Molecular mechanism of visual transduction

Abstract

European Journal of BiochemistryVolume 179, Issue 2 p. 255-266 Free Access Molecular mechanism of visual transduction Marc CHABRE, Corresponding Author Marc CHABRE Laboratoire de Biophysique Moléculaire et Cellulaire (Unité Associée 520 au CNRS), Département Recherche Fondamentale, Centre ďÉtudes Nucléaires, GrenobleCorrespondence to M. Chabre, Laboratoire de Biophysique Moléculaire et Cellulaire. CENG Boîte Postale 85X, F-38041 Grenoble, FranceSearch for more papers by this authorPhilippe DETERRE, Philippe DETERRE Laboratoire de Biophysique Moléculaire et Cellulaire (Unité Associée 520 au CNRS), Département Recherche Fondamentale, Centre ďÉtudes Nucléaires, GrenobleSearch for more papers by this author Marc CHABRE, Corresponding Author Marc CHABRE Laboratoire de Biophysique Moléculaire et Cellulaire (Unité Associée 520 au CNRS), Département Recherche Fondamentale, Centre ďÉtudes Nucléaires, GrenobleCorrespondence to M. Chabre, Laboratoire de Biophysique Moléculaire et Cellulaire. CENG Boîte Postale 85X, F-38041 Grenoble, FranceSearch for more papers by this authorPhilippe DETERRE, Philippe DETERRE Laboratoire de Biophysique Moléculaire et Cellulaire (Unité Associée 520 au CNRS), Département Recherche Fondamentale, Centre ďÉtudes Nucléaires, GrenobleSearch for more papers by this author First published: February 1989 https://doi.org/10.1111/j.1432-1033.1989.tb14549.xCitations: 273 This review is dedicated to the memory of our friend hermann kühn, a poineer of the biochemistry of visual transduction AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abbreviations ROS rod outer segment R* photoexcited rhodopsin T2GDP T2GTP, T2empty, α-subunit of transducin bearing a GDP, a GTP, or with an empty site T Tγ, β and γ subunit of transducin PDE cGMP-specific phosphodiesterase PDEαβ catalytic subunits of PDE I inhibitory subunit of PDE GDP[βS] guanosine 5′-[β-thio]diphosphate GTP[γS] guanosine 5′-[γ-thio]triphosphate GuoPP[NH]P guanosine 5′-[β,γ-imino]triphosphate Enzymes cGMP-specific phosphodiesterase (EC 3.1.4.35) guanylate cyclase (EC 4.6.1.2) REFERENCES 1a. Stryer, L. (1986) Annu. Rev. Neurosci. 9, 87– 119. CrossrefCASPubMedWeb of Science®Google Scholar 1b. Nathans, J. (1987) Annu. Rev. Neurosci. 10, 163– 194. CrossrefCASPubMedWeb of Science®Google Scholar 2 Applebury, M. L. & Hargrave, P. A. (1986) Vision Res. 26, 1881– 1895. CrossrefCASPubMedWeb of Science®Google Scholar 3a. Pugh, E. N. (1987) Annu. Rev. Physiol. 49, 715– 742. CrossrefCASPubMedWeb of Science®Google Scholar 3b. Liebman, P. A., Parker, K. R. & Dratz, E. A. (1987) Annu. Rev. Physiol. 49, 765– 792. CrossrefCASPubMedWeb of Science®Google Scholar 3c. Hurley, J. B. (1987) Annu. Rev. Physiol. 49, 793– 812. CrossrefCASPubMedWeb of Science®Google Scholar 4 Hagins, W. A. (1972) Annu. Rev. Biophys. Bioeng. 1, 131– 158. CrossrefCASPubMedWeb of Science®Google Scholar 5 Kühn, H. (1978) Biochemistry 17, 4389– 4395. CrossrefPubMedWeb of Science®Google Scholar 6 Kühn, H. (1980) Nature (Lond.) 283, 587– 589. CrossrefCASPubMedWeb of Science®Google Scholar 7 Kühn, H. (1984) in Progress in retinal research ( N. Osborne & J. Chader, eds) pp. 123– 153, Pergamon, New York . Google Scholar 8 Fung, B. K. K., Hurley, J. B. & Stryer, L. (1981) Proc. Natl Acad. Sci. USA 78, 152– 156. CrossrefCASPubMedWeb of Science®Google Scholar 9 Yee, R. & Liebman, P. A. (1978) J. Biol. Chem. 253, 8902– 8909. CASPubMedWeb of Science®Google Scholar 10 Fesenko, E. E., Kolesnikov, S. S. & Lyubrsky, A. L. (1985) Nature (Lond.) 313, 310– 313. CrossrefCASPubMedWeb of Science®Google Scholar 11 Cook, J. N., Hanke, W. & Kaupp, U. B. (1987) Proc. Natl Acad. Sci. USA 84, 585– 589. CrossrefCASPubMedWeb of Science®Google Scholar 12 Fleischman, D. & Denisevich, M. (1979) Biochemistry 18, 5060– 5066. CrossrefCASPubMedWeb of Science®Google Scholar 13 Lolley, R. N. & Racz, E. (1982) Vision Res. 22, 1481– 1486. CrossrefCASPubMedWeb of Science®Google Scholar 14 Koch, K. W. & Stryer, L. (1988) Nature (Lond.) 334, 64– 66. CrossrefCASPubMedWeb of Science®Google Scholar 15 Yau, K. W. & Nakatani, K. (1985) Nature (Lond.) 313, 579– 581. CrossrefCASPubMedWeb of Science®Google Scholar 16 Pugh, E. & Altman, J. (1988) Nature (Lond.) 313, 16– 17. CrossrefWeb of Science®Google Scholar 17 Stryer, L. & Bourne, H. R. (1986) Annu. Rev. Cell Biol. 2, 391– 419. CrossrefCASPubMedWeb of Science®Google Scholar 18 Dohlman, H. G., Caron, M. G. & Lefkowitz, R. J. (1987 Biochemistry 26, 2657– 2664. CrossrefCASPubMedWeb of Science®Google Scholar 19 Pfister, C., Chabre, M