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Prevalence and characteristics of noncompliant behaviour and its risk factors in kidney transplant recipients
Open accessAbstract
Noncompliance with therapy is one possible explanation for the observation that long-term graft survival is not sufficiently improved by the development in immunosuppression. The aim of the study was to explore the prevalence, characteristics and risk factors of noncompliance with immunosuppression. A total of 161 adult kidney transplant recipients were interviewed about their self-rated health, social support, education, stress from adverse effects and compliance with the immunosuppression. The prevalence of subclinical noncompliance was 54%. Noncompliant patients declared significantly worse self-rated health, less satisfaction with social support and higher stress from adverse effects. Male gender (OR 7.5, CI 2.4-23.39), high stress from adverse effects (OR 12.27, CI 2.44-61.88), fair self-rated health (OR 4.45, CI 1.04-19.55) and fair satisfaction with social support (OR 4.55, CI 1.08-19.24) were predictors of noncompliance. Standardized detection methods should be developed with the aim of identifying patients who are at risk of noncompliance in order to prevent graft loss.
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Metadata
- Authors
- Rosenberger, J., Geckova, A. M., Dijk, J. P., Nagyova, I., Roland, R., Heuvel, W. J. A., & Groothoff, J. W.
- Venue
- Transplant International
- Publisher
- Frontiers Media SA
- Published
- 2005-09
- Volume
- 18
- Issue
- 9
- Pages
- 1072-1078
- ISSN
- 0934-0874 (ISSN-L)
- 1432-2277
- OpenAlex
- W2167761867
- Cited by
- 283
- References
- 0
- FWCI
- 9.86
- Type
- journal article
- Language
- en
- Open access
- green
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- Rosenberger, J., Geckova, A. M., Dijk, J. P., Nagyova, I., Roland, R., Heuvel, W. J. A., & Groothoff, J. W. (2005). Prevalence and characteristics of noncompliant behaviour and its risk factors in kidney transplant recipients. Transplant International. https://doi.org/10.1111/j.1432-2277.2005.00183.x
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