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Prevalence and characteristics of noncompliant behaviour and its risk factors in kidney transplant recipients

Open access
Rosenberger, Jaroslav, Geckova, Andrea Madarasova, Dijk, Jitse P., Nagyova, Iveta, Roland, Robert, Heuvel, Wim J. A., Groothoff, Johan W.·2005·Transplant International

Abstract

Noncompliance with therapy is one possible explanation for the observation that long-term graft survival is not sufficiently improved by the development in immunosuppression. The aim of the study was to explore the prevalence, characteristics and risk factors of noncompliance with immunosuppression. A total of 161 adult kidney transplant recipients were interviewed about their self-rated health, social support, education, stress from adverse effects and compliance with the immunosuppression. The prevalence of subclinical noncompliance was 54%. Noncompliant patients declared significantly worse self-rated health, less satisfaction with social support and higher stress from adverse effects. Male gender (OR 7.5, CI 2.4-23.39), high stress from adverse effects (OR 12.27, CI 2.44-61.88), fair self-rated health (OR 4.45, CI 1.04-19.55) and fair satisfaction with social support (OR 4.55, CI 1.08-19.24) were predictors of noncompliance. Standardized detection methods should be developed with the aim of identifying patients who are at risk of noncompliance in order to prevent graft loss.

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Crossref · 10.1111/j.1432-2277.2005.00183.x

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Metadata

Authors
Rosenberger, J., Geckova, A. M., Dijk, J. P., Nagyova, I., Roland, R., Heuvel, W. J. A., & Groothoff, J. W.
Venue
Transplant International
Published
2005-09
Volume
18
Issue
9
Pages
1072-1078
ISSN
  • 0934-0874 (ISSN-L)
  • 1432-2277
OpenAlex
W2167761867
Cited by
283
References
0
FWCI
9.86
Type
journal article
Language
en
Open access
green

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