The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Liver lipid metabolism
Abstract
Summary: The liver plays a key role in lipid metabolism. Depending on species it is, more or less, the hub of fatty acid synthesis and lipid circulation through lipoprotein synthesis. Eventually the accumulation of lipid droplets into the hepatocytes results in hepatic steatosis, which may develop as a consequence of multiple dysfunctions such as alterations in β‐oxidation, very low density lipoprotein secretion, and pathways involved in the synthesis of fatty acids. In addition an increased circulating pool of non‐esterified fatty acid may also to be a major determinant in the pathogenesis fatty liver disease. This review also focuses on transcription factors such as sterol‐regulatory‐element‐binding protein‐1c and peroxisome proliferator‐activated receptor alpha, which promote either hepatic fatty acid synthesis or oxidation.
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Citations
Cites
Liver X receptors as integrators of metabolic and inflammatory signaling
Zelcer, N. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27883 · Cited by 978
Mechanisms of Hepatic Very Low-Density Lipoprotein Overproduction in Insulin Resistance
Adeli, K., Taghibiglou, C., Van Iderstine, S. C., & Lewis, G. F. (2001) · Trends in Cardiovascular Medicine · doi:10.1016/s1050-1738(01)00084-6 · Cited by 194
Cited by
Adipose tissue dysfunction as determinant of obesity-associated metabolic complications
Longo, M., Zatterale, F., Naderi, J., Parrillo, L., Formisano, P., Raciti, G. A., Beguinot, F., & Miele, C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20092358 · Cited by 1,575
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
Ipsen, D. H., Lykkesfeldt, J., & Tveden-Nyborg, P. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2860-6 · Cited by 1,471
Decoding cell death signals in liver inflammation
Brenner, C., Galluzzi, L., Kepp, O., & Kroemer, G. (2013) · Journal of Hepatology · doi:10.1016/j.jhep.2013.03.033 · Cited by 1,022
Rutkowski, D. T., Wu, J., Back, S.-H., Callaghan, M. U., Ferris, S. P., Iqbal, J., Clark, R., Miao, H., Hassler, J. R., Fornek, J., et al. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.10.015 · Cited by 580
Recent insights into the pathogenesis of nonalcoholic fatty liver disease
Arab, J. P., Arrese, M., & Trauner, M. (2018) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-020117-043617 · Cited by 573
Metadata
- Authors
- Nguyen, P., Leray, V., Diez, M., Serisier, S., Bloc’h, J. L., Siliart, B., & Dumon, H.
- Venue
- Journal of Animal Physiology and Animal Nutrition
- Publisher
- Wiley
- Published
- 2008-06
- Volume
- 92
- Issue
- 3
- Pages
- 272-283
- ISSN
- 0931-2439 (ISSN-L)
- 1439-0396
- OpenAlex
- W2066839216
- Cited by
- 968
- References
- 2
- FWCI
- 7.66
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nguyen, P., Leray, V., Diez, M., Serisier, S., Bloc’h, J. L., Siliart, B., & Dumon, H. (2008). Liver lipid metabolism. Journal of Animal Physiology and Animal Nutrition. https://doi.org/10.1111/j.1439-0396.2007.00752.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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