The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Acute suicidality after commencing atomoxetine
Abstract
An 11 year old boy developed acute agitation and suicidal ideation after commencing atomoxetine shortly after it was approved for use in Australia. The clinical features were similar to reactions described in response to selective serotonin reuptake inhibitors. The case highlights the importance of close monitoring when starting newly registered medications. An increased risk of suicidal thinking was subsequently identified for this drug leading to a Food and Drug Administration alert and a boxed warning in September 2005, however there are still no other published case reports of acute suicidality.
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Atomoxetine has been rarely associated with acute suicidality and has a black box warning.
“Because atomoxetine has been rarely associated with acute suicidality [86], it has been given a 'black box' warning.”
From Advances in understanding and treating ADHD (2011) · cites this paper as [86]
Citations
Cites
A method for estimating the probability of adverse drug reactions
Naranjo, C. A., Busto, U., Sellers, E. M., Sandor, P., Ruiz, I., Roberts, E. A., Janecek, E., Domecq, C., & Greenblatt, D. J. (1981) · Clinical Pharmacology and Therapeutics · doi:10.1038/clpt.1981.154 · Cited by 11,914
Whittington, C. J., Kendall, T., Fonagy, P., Cottrell, D., Cotgrove, A., & Boddington, E. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16043-1 · Cited by 1,006
CYP2D6 and Clinical Response to Atomoxetine in Children and Adolescents With ADHD
MICHELSON, D., READ, H. A., RUFF, D. D., WITCHER, J., ZHANG, S., & McCRACKEN, J. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000246056.83791.b6 · Cited by 159
CYP2D6 metabolizer status and atomoxetine dosing in children and adolescents with ADHD
Trzepacz, P. T., Williams, D. W., Feldman, P. D., Wrishko, R. E., Witcher, J. W., & Buitelaar, J. K. (2007) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2007.06.002 · Cited by 65
Low-Dose Atomoxetine for Maintenance Treatment of Attention-Deficit/Hyperactivity Disorder
Newcorn, J. H., Michelson, D., Kratochvil, C. J., Allen, A. J., Ruff, D. D., Moore, R. J., & for the Atomoxetine Low-dose Study Group (2006) · PEDIATRICS · doi:10.1542/peds.2005-2999 · Cited by 34
Mania Induction Associated With Atomoxetine
Henderson, T. A. (2004) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000139760.11458.aa · Cited by 31
A case of mania associated with tomoxetine
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Suicidal ideation among children taking atomoxetine (Strattera)
Wooltorton, E. (2005) · Canadian Medical Association Journal · doi:10.1503/cmaj.051474 · Cited by 25
Isolated atomoxetine (Strattera™) ingestions commonly result in toxicity
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Children and Adolescent Exposures to Atomoxetine Hydrochloride Reported to a Poison Control Center
Stojanovski, S. D., Robinson, R. F., Baker, D., Casavant, M. J., Hayes, J. R., & Nahata, M. C. (2006) · Clinical Toxicology · doi:10.1080/15563650600584311 · Cited by 16
Warning on Strattera for attention-deficit hyperactivity disorder.
(2006) · PubMed · Cited by 1
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Research works printed but not linked: 1
- Caswell A, 2004, Strattera. Atomoxetine Hydrochloride Product Information. MIMS Annual
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Sorted by citations
Advances in understanding and treating ADHD
Antshel, K. M., Hargrave, T. M., Simonescu, M., Kaul, P., Hendricks, K., & Faraone, S. V. (2011) · BMC Medicine · doi:10.1186/1741-7015-9-72 · Cited by 140
Metadata
- Authors
- Paxton, G. A., & Cranswick, N. E.
- Affiliations
- Royal Children's Hospital (AU)
- Corresponding author
- Paxton, Georgia Armat
- Venue
- Journal of Paediatrics and Child Health
- Publisher
- Wiley
- Published
- 2008-09-24
- Volume
- 44
- Issue
- 10
- Pages
- 596-598
- ISSN
- 1034-4810 (ISSN-L)
- 1440-1754
- OpenAlex
- W2116073975
- Cited by
- 22
- References
- 11
- Citations by year
- 2025: 2 · 2023: 1 · 2022: 1 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 1 · 2014: 2 · 2012: 1
- FWCI
- 1.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Paediatrics and Child Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Keywords
- atomoxetine, suicidality, suicidal ideation, agitation, adverse drug reactions, selective serotonin reuptake inhibitors, children with ADHD, pharmacovigilance, FDA warning, black box warning
- MeSH terms
- Atomoxetine Hydrochloride, Attention Deficit Disorder with Hyperactivity, Child, Humans, Male, Propylamines, Suicide, Attempted, Adrenergic Uptake Inhibitors
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