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Cited by 466

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Update on tuberculous pleural effusion

Open access
LIGHT, Richard W.·2010·Respirology

Abstract

The possibility of tuberculous pleuritis should be considered in every patient with an undiagnosed pleural effusion, for if this diagnosis is not made the patient will recover only to have a high likelihood of subsequently developing pulmonary or extrapulmonary tuberculosis Between 3% and 25% of patients with tuberculosis will have tuberculous pleuritis. The incidence of pleural tuberculosis is higher in patients who are HIV positive. Tuberculous pleuritis usually presents as an acute illness with fever, cough and pleuritic chest pain. The pleural fluid is an exudate that usually has predominantly lymphocytes. Pleural fluid cultures are positive for Mycobacterium tuberculosis in less than 40% and smears are virtually always negative. The easiest way to establish the diagnosis of tuberculous pleuritis in a patient with a lymphocytic pleural effusion is to generally demonstrate a pleural fluid adenosine deaminase level above 40 U/L. Lymphocytic exudates not due to tuberculosis almost always have adenosine deaminase levels below 40 U/L. Elevated pleural fluid levels of γ‐interferon also are virtually diagnostic of tuberculous pleuritis in patients with lymphocytic exudates. In questionable cases the diagnosis can be established by demonstrating granulomas or organisms on tissue specimens obtained via needle biopsy of the pleura or thoracoscopy. The chemotherapy for tuberculous pleuritis is the same as that for pulmonary tuberculosis.

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Metadata

Authors
LIGHT, R. W.
Venue
Respirology
Publisher
Wiley
Published
2010-03-29
Volume
15
Issue
3
Pages
451-458
ISSN
  • 1323-7799 (ISSN-L)
  • 1440-1843
OpenAlex
W2137852718
Cited by
466
References
41
FWCI
10.33
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Update on tuberculous pleural effusion. https://app.cochat.ai/papers/10.1111/j.1440-1843.2010.01723.x
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LIGHT, R. W. (2010). Update on tuberculous pleural effusion. Respirology. https://doi.org/10.1111/j.1440-1843.2010.01723.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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