The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Do cigarette smokers with erectile dysfunction benefit from stopping?: a prospective study
Abstract
OBJECTIVE: To assess whether stopping smoking can improve erectile dysfunction (ED) in smokers, as cigarette smoking is a known risk factor for ED. PATIENTS AND METHODS: Smokers who requested nicotine replacement therapy (NRT) and complained of ED were first evaluated for hypertension, dyslipidaemia, diabetes, psychiatric disorders and drug history. The grade of ED in smokers with none of these risk factors was then determined using the five‐item version of the International Index of Erectile Function (IIEF‐5) before NRT, and the grading repeated after 1 year of follow‐up. The correlation between the exposure to smoking (pack‐years) and severity of ED was assessed before the follow‐up. The ED status between patients who stopped smoking after NRT and those who continued during the follow‐up was then compared before and after the follow‐up. RESULTS: The severity of ED correlated significantly with the level of exposure to smoking. Age and ED status before the follow‐up were not significantly different between 118 patients who stopped (ex‐smokers) and 163 who continued smoking (current smokers). After 1 year the ED status improved in ≥ 25% of ex‐smokers but in none of the current smokers; 2.5% of ex‐smokers and 6.8% of current smokers had a deterioration in ED. Ex‐smokers had a significantly better ED status after the follow‐up ( P = 0.009). Among ex‐smokers, patients with advanced ED and those who were older had less improvement. CONCLUSION: There is a strong association between the intensity of cigarette smoking and degree of ED. Stopping cigarette smoking can improve ED in a considerable proportion of smokers. Age and the severity of ED before stopping are inversely related to the chance of improvement.
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Stary, H. C., Chandler, A. B., Dinsmore, R. E., Fuster, V., Glagov, S. K., Insull, W., Rosenfeld, M. E., Schwartz, C. J., Wagner, W. D., & Wissler, R. W. (1995) · Circulation · doi:10.1161/01.cir.92.5.1355 · Cited by 3,506
Rosen, R., Cappelleri, J. C., Smith, M., Lipsky, J., & Peña, B. (1999) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3900472 · Cited by 3,095
Celermajer, D. S., Sørensen, K. E., Georgakopoulos, D., Bull, C., Thomas, O., Robinson, J. T. C., & Deanfield, J. E. (1993) · Circulation · doi:10.1161/01.cir.88.5.2149 · Cited by 1,532
(1992) · doi:10.1126/science.1378650 · Cited by 1,163
JOHANNES, C. B., ARAUJO, A. B., FELDMAN, H. A., DERBY, C. A., KLEINMAN, K. P., & McKINLAY, J. B. (2000) · Journal of Urology · doi:10.1016/s0022-5347(05)67900-1 · Cited by 1,158
Rajfer, J., Aronson, W. J., Bush, P. A., Dorey, F. J., & Ignarro, L. J. (1992) · New England Journal of Medicine · doi:10.1056/nejm199201093260203 · Cited by 1,006
Stary, H. C., Chandler, A. B., Dinsmore, R. E., Fuster, V., Glagov, S. K., Insull, W., Rosenfeld, M. E., Schwartz, C. J., Wagner, W. D., & Wissler, R. W. (1995) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.15.9.1512 · Cited by 959
Passive Smoking and Impaired Endothelium-Dependent Arterial Dilatation in Healthy Young Adults
Celermajer, D. S., Adams, M. R., Clarkson, P., Robinson, J. T. C., McCredie, R. J., Donald, A. E., & Deanfield, J. E. (1996) · New England Journal of Medicine · doi:10.1056/nejm199601183340303 · Cited by 907
Feldman, H. A., Johannes, C. B., Derby, C. A., Kleinman, K. P., Mohr, B. A., Araujo, A. B., & McKinlay, J. B. (2000) · Preventive Medicine · doi:10.1006/pmed.2000.0643 · Cited by 748
Relative and Absolute Excess Risks of Coronary Heart Disease among Women Who Smoke Cigarettes
Willett, W. C., Green, A. C., Stampfer, M. J., Speizer, F. E., Colditz, G. A., ROSNER, B. A., Monson, R. R., Stason, W. B., & Hennekens, C. H. (1987) · New England Journal of Medicine · doi:10.1056/nejm198711193172102 · Cited by 608
(1991) · doi:10.1172/jci115266 · Cited by 429
Peripheral arterial disease - epidemiological aspects
Criqui, M. H. (2001) · Vascular Medicine · doi:10.1177/1358836x0100600i102 · Cited by 352
The Risk of Myocardial Infarction after Quitting Smoking in Men under 55 Years of Age
Rosenberg, L. A., Kaufman, D. W., Helmrich, S. P., & Shapiro, S. (1985) · New England Journal of Medicine · doi:10.1056/nejm198512123132404 · Cited by 324
Smoking Cessation and the Risk of Stroke in Middle-aged Men
Wannamethee, S. G. (1995) · JAMA · doi:10.1001/jama.1995.03530020073035 · Cited by 309
The risk of myocardial infarction after quitting smoking in men under 55 years of age.
Rosenberg, L. A. (1986) · Plastic & Reconstructive Surgery · doi:10.1097/00006534-198678060-00100 · Cited by 305
Cigarette smoking and the risk of diabetes in women.
Rimm, E. B., Manson, J. E., Stampfer, M. J., Colditz, G. A., Willett, W. C., ROSNER, B. A., Hennekens, C. H., & Speizer, F. E. (1993) · American Journal of Public Health · doi:10.2105/ajph.83.2.211 · Cited by 280
Vascular damage from smoking: disease mechanisms at the arterial wall
Powell, J. T. (1998) · Vascular Medicine · doi:10.1177/1358836x9800300105 · Cited by 276
Causation and Causal Inference
(2008) · Sage eBooks · doi:10.4135/9781412953948.n63 · Cited by 236
SMOKING AND ERECTILE DYSFUNCTION: EVIDENCE BASED ANALYSIS
McVARY, K. T., CARRIER, S., WESSELLS, H., & the SUBCOMMITTEE ON SMOKING AND ERECTILE DYSFUNCTION SOCIOECONOMIC COMMITTEE, S. M. S. O. N. A. (2001) · Journal of Urology · doi:10.1016/s0022-5347(05)65641-8 · Cited by 201
(1994) · doi:10.1093/oxfordjournals.aje.a117189 · Cited by 193
Cavender, J. B., Rogers, W. J., Fisher, L. D., Gersh, B. J., Coggin, C. J., & Myers, W. O. (1992) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(92)90092-2 · Cited by 177
Rosen, M. P., Greenfield, A. J., Walker, T. G., Grant, P., Dubrow, J., Bettmann, M. A., Fried, L. E., & Goldstein, I. (1991) · The Journal of Urology · doi:10.1016/s0022-5347(17)38444-6 · Cited by 155
Poredoš, P., Orehek, M., Tratnik, E., & Poredoš, P. (1999) · Angiology · doi:10.1177/000331979905000304 · Cited by 143
Polidori, M. C., Mecocci, P., Stahl, W., & Sies, H. (2003) · British Journal Of Nutrition · doi:10.1079/bjn2003890 · Cited by 111
Rothman, K. J. (1998) · Epidemiology · doi:10.1097/00001648-199805000-00019 · Cited by 105
Axelsen, M., Eliasson, B., JOHEIM, E., Lenner, R. A., Taskinen, M., & Smith, U. (1995) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.1995.tb00869.x · Cited by 93
Cessation of Smoking Rapidly Decreases erectile Dysfunction
Guay, A. T., Perez, J. B., & Heatley, G. J. (1998) · Endocrine Practice · doi:10.4158/ep.4.1.23 · Cited by 72
Nocturnal penile tumescence in cigarette smokers with erectile dysfunction
Hirshkowitz, M., Arcasoy, M. O., Karacan, I., WILLIAMS, R. L., & Howell, J. W. (1992) · Urology · doi:10.1016/0090-4295(92)90263-v · Cited by 65
Lifestyle factors and coagulation activation markers: the Caerphilly Study
YARNELL, J. W. G., Sweetnam, P. M., Rumley, A., & Lowe, G. D. O. (2001) · Blood Coagulation & Fibrinolysis · doi:10.1097/00001721-200112000-00015 · Cited by 54
Cigarette smoking and the age at onset of a first non-fatal myocardial infarction
Gottlieb, S., Fallavollita, J. A., McDermott, M., Brown, M., Eberly, S. W., & Moss, A. J. (1994) · Coronary Artery Disease · doi:10.1097/00019501-199408000-00007 · Cited by 19
Kunz, J. (2002) · Gerontology · doi:10.1159/000065248 · Cited by 7
Research works printed but not linked: 2
- National Institutes of Health Consensus Development Panel On Impotence., 1993, Proceedings of a conference held December 7–9, 1992 in Bethesda MD, J Am Med Assoc, 270, 83
- Lewis RW, Erectile Dysfunction., :
Cited by
Sorted by citations
Yafi, F. A., Jenkins, L., Albersen, M., Corona, G., Isidori, A. M., Goldfarb, S., Maggi, M., Nelson, C. J., Parish, S., Salonia, A., et al. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.3 · Cited by 853
Anatomy, Physiology, and Pathophysiology of Erectile Dysfunction
Gratzke, C., Angulo, J., Chitaley, K., Dai, Y.-T., Kim, N. N., Paick, J.-S., Simonsen, U., Ückert, S., Wespes, E., Andersson, K. E., et al. (2010) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01624.x · Cited by 476
A Population-Based, Longitudinal Study of Erectile Dysfunction and Future Coronary Artery Disease
Inman, B. A., Sauver, J. L. S., Jacobson, D. J., McGree, M. E., Nehra, A. X., Lieber, M. M., Roger, V. L., & Jacobsen, S. J. (2009) · Mayo Clinic Proceedings · doi:10.4065/84.2.108 · Cited by 422
Smoking and Male Infertility: An Evidence-Based Review
Harlev, A., Agarwal, A. K., Gunes, S. O., Shetty, A., & du Plessis, S. S. (2015) · The World Journal of Men s Health · doi:10.5534/wjmh.2015.33.3.143 · Cited by 292
Lifestyles and sexuality in men and women: the gender perspective in sexual medicine
Mollaioli, D., Ciocca, G., Limoncin, E., Sante, S. D., Gravina, G. L., Carosa, E., Lenzi, A., & Jannini, E. A. (2020) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-019-0557-9 · Cited by 226
Metadata
- Authors
- Pourmand, G., Alidaee, M. R., Rasuli, S., Maleki, A., & Mehrsai, A.
- Affiliations
- Tehran University of Medical Sciences (IR)
- Corresponding author
- Pourmand, Gholamreza
- ORCID
- Pourmand, Gholamreza
- Venue
- BJU International
- Publisher
- Wiley
- Published
- 2004-12
- Volume
- 94
- Issue
- 9
- Pages
- 1310-1313
- ISSN
- 1464-4096 (ISSN-L)
- 1464-410X
- OpenAlex
- W1979246926
- Semantic Scholar
- 872d2dd3eb225097d908946155f228573ac42a75
- Cited by
- 113
- References
- 30
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 6 · 2023: 7 · 2022: 7 · 2021: 7 · 2020: 10 · 2019: 6 · 2018: 1 · 2017: 5 · 2016: 12 · 2015: 7 · 2014: 8 · 2013: 4 · 2012: 4
- FWCI
- 1.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- British Journal of Urology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Keywords
- erectile dysfunction, cigarette smoking, smoking cessation, nicotine replacement therapy, pack-years, IIEF-5, ED severity, risk factors
- MeSH terms
- Adult, Follow-Up Studies, Humans, Erectile Dysfunction, Male, Middle Aged, Prognosis, Prospective Studies, Risk Factors, Smoking, Smoking Cessation
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