Cited by 299Migraine and Headache StudiesTemporomandibular Joint DisordersTraumatic Brain Injury Research

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Psychiatric Comorbidity in Migraine: A Review

Radat, F, Swendsen, J·2005·Cephalalgia

DOI 10.1111/j.1468-2982.2004.00839.x

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Abstract

Investigations of migraine comorbidity have confirmed its association with diverse psychiatric conditions. This association appears to be strongest for major depression and anxiety disorders (particularly panic and phobia), but increased comorbidity has also been reported with substance abuse and certain mood disorders. This literature also indicates that greater psychiatric comorbidity exists for migraine sufferers with aura than without. Some support is found for the notion that psychiatric comorbidity is higher in transformed migraine than in simple migraine (particularly in the case of chronic substance abuse). However, research into the possible mechanisms underlying these associations remains limited. Studies examining the order of onset and the cross-transmission of migraine and psychiatric disorders in families have been unable to distinguish fully between causal and common aetiological models of association. The conclusions are discussed in light of both methodological and conceptual issues relevant to understanding migraine comorbidity.

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Carreño, O. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
Additional file 1 of Risk of major mental disorders in the offspring of parents with migraine
Li, D.-J., Tsai, S.-J., Chen, T.-J., Liang, C.-S., & Chen, M.-H. (2024) · Figshare · doi:10.6084/m9.figshare.26085107
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Clinical trajectories and genetic architecture across the neurological–psychiatric boundaryPreprint
Kopál, J., Smeland, O. B., Hagen, E., Amanzadi, A., Erdõs, B., Fuhrer, J., Shadrin, A. A., Frei, O., van der Meer, D., O’Connell, K. S., et al. (2026) · medRxiv · doi:10.64898/2026.08.06.26359855

Authors: Radat, F., & Swendsen, J.
Affiliations: Chronic Pain Treatment Unit, Centre Hospitalo-universitaire
Université de Bordeaux (FR)
Corresponding author: Radat, F
ORCID: Radat, F
Swendsen, J
Venue: Cephalalgia
Publisher: SAGE Publications
Published: 2005-03
Volume: 25
Issue: 3
Pages: 165-178
ISSN: 0333-1024 (ISSN-L)
1468-2982
DOI: 10.1111/j.1468-2982.2004.00839.x
OpenAlex: W2085382852
Cited by: 299
References: 36
Citations by year: 2026: 6 · 2025: 12 · 2024: 11 · 2023: 6 · 2022: 6 · 2021: 16 · 2020: 11 · 2019: 11 · 2018: 9 · 2017: 8 · 2016: 11 · 2015: 18 · 2014: 16 · 2013: 23 · 2012: 16
FWCI: 12.63
Type: journal article
Language: en
Open access: closed
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Cephalalgia (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
Health Sciences › Dentistry › Oral Surgery › Temporomandibular Joint Disorders
Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
Keywords: migraine, psychiatric comorbidity, major depressive disorder, anxiety disorders, panic disorder, phobia, substance abuse, mood disorders, migraine with aura, chronic migraine, familial aggregation
MeSH terms: Mental Disorders, Clinical Trials as Topic, Humans, Migraine Disorders, Risk Factors, Comorbidity, Risk Assessment

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Psychiatric Comorbidity in Migraine: A Review

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