Louis Pasteur, from crystals of life to vaccination
Open accessAbstract
Louis Pasteur (1822-1895) is an exceptional scientist who opened a new era in medicine and biology. Starting from studies on crystals of by-products of wine fermentation, he first defined a distinct chemistry between dead and living matters. He then showed the role of living microbes in the fermentation and putrefaction processes. This brought him to challenge the two-millennium-old theory of spontaneous generation, using remarkably well-designed experiments. His observations on epidemics in silkworms allowed him to demonstrate the role of specific germs in infectious diseases. His discovery of the vaccine against fowl cholera can be considered as the birth of immunology. Finally, he became universally recognized through his famous vaccinations against anthrax and rabies.
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Pasteur's detailed notes on silkworm epidemics enabled him to demonstrate the critical role of specific germs in contagious diseases.
“His detailed notes on silkworm epidemics enabled him to demonstrate the critical role of specific germs in contagious diseases [9].”
From Louis Pasteur: A Legacy Unmasked (2024) · cites this paper as [9]
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Brogren, C. (2024) · APMIS · doi:10.1111/apm.13325 · Cited by 10 · see citing works
Louis Pasteur: A Legacy Unmasked
Jambholkar, P. C., Choudhari, S. G., & Sharma, M. (2024) · Cureus · doi:10.7759/cureus.68080 · Cited by 3 · see citing works
- Authors
- Berche, P.
- Affiliations
- Hôpital Necker-Enfants Malades (FR)
- Corresponding author
- Berche, P.
- ORCID
- Berche, P.
- Venue
- Clinical Microbiology and Infection
- Publisher
- Elsevier BV
- Published
- 2012-10
- Volume
- 18
- Pages
- 1-6
- ISSN
- 1198-743X (ISSN-L)
- OpenAlex
- W2135300467
- Cited by
- 129
- References
- 0
- Citations by year
- 2026: 22 · 2025: 9 · 2024: 15 · 2023: 15 · 2022: 15 · 2021: 18 · 2020: 11 · 2019: 8 · 2018: 4 · 2017: 2 · 2016: 5 · 2015: 4 · 2014: 1
- FWCI
- 1.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Clinical Microbiology and Infection (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Historical Medical Research and Treatments
- Social Sciences › Arts and Humanities › History and Philosophy of Science › History of Science and Medicine
- Social Sciences › Arts and Humanities › History › Medical History and Innovations
- Keywords
- Louis Pasteur, history of microbiology, spontaneous generation, wine fermentation, putrefaction, microbial fermentation, infectious diseases, anthrax vaccination, rabies vaccination
- MeSH terms
- Allergy and Immunology, Anthrax, History of Medicine, Humans, Microbiology, Rabies, Vaccination, Veterinary Medicine, History, 19th Century
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