The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
A Broader Phenotype of Autism: The Clinical Spectrum in Twins
Abstract
The diagnostic boundaries of the behavioural phenotype for autism were examined in 28 MZ pairs and 20 DZ same‐sex twin pairs, where one or both twins had autism. In the non‐autistic cotwin (i.e. In twin pairs discordant for autism) it was common to find language impairments in childhood and social deficits persisting into adulthood. Concordance for this broader phenotype was much greater in MZ pairs than DZ pairs, indicating a strong genetic component. Behavioural and cognitive manifestations of autism were compared both within and between MZ twin pairs. The variation was as great within MZ twin pairs as between pairs, suggesting that it does not index genetic heterogeneity (although aetiological heterogeneity probably exists). Current diagnostic practices need re‐evaluation.
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Cites
Lord, C., Rutter, M., & Le Couteur, A. (1994) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02172145 · Cited by 9,065
Self-citationAutism as a strongly genetic disorder: evidence from a British twin study
Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., & Rutter, M. (1995) · Psychological Medicine · doi:10.1017/s0033291700028099 · Cited by 2,461
Self-citationLord, C., Rutter, M., Goode, S., Heemsbergen, J., Jordan, H., Mawhood, L., & Schopler, E. (1989) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02211841 · Cited by 2,030
Self-citationINFANTILE AUTISM: A GENETIC STUDY OF 21 TWIN PAIRS
Folstein, S., & Rutter, M. (1977) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1977.tb00443.x · Cited by 1,361
Self-citationA case-control family history study of autism
Bolton, P., Macdonald, H., Pickles, A., Rios, P., Goode, S., Crowson, M., Bailey, A., & Rutter, M. (1994) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1994.tb02300.x · Cited by 1,094
Self-citationGenetic influences and infantile autism
FOLSTEIN, S., & RUTTER, M. (1977) · Nature · doi:10.1038/265726a0 · Cited by 400
Self-citationSiblings and parents of children with autism: a controlled population-based study
Gillberg, C., Gillberg, I. C., & Steffenburg, S. (1992) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1992.tb11450.x · Cited by 94
Cited by
Model of autism: increased ratio of excitation/inhibition in key neural systems
Rubenstein, J. L. R., & Merzenich, M. M. (2003) · Genes, Brain and Behavior · doi:10.1034/j.1601-183x.2003.00037.x · Cited by 2,768
Autism as a strongly genetic disorder: evidence from a British twin study
Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., & Rutter, M. (1995) · Psychological Medicine · doi:10.1017/s0033291700028099 · Cited by 2,461
Self-citationAutistic Traits in the General Population: A Twin Study
Constantino, J. N., & Todd, R. D. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.5.524 · Cited by 1,317
The Epidemiology of Autism Spectrum Disorders
Newschaffer, C. J., Croen, L. A., Daniels, J., Giarelli, E., Grether, J. K., Levy, S. E., Mandell, D. S., Miller, L. A., Pinto-Martin, J., Reaven, J., et al. (2007) · Annual Review of Public Health · doi:10.1146/annurev.publhealth.28.021406.144007 · Cited by 1,228
Muhle, R., Trentacoste, S. V., & Rapin, I. (2004) · Pediatrics · doi:10.1542/peds.113.5.e472 · Cited by 1,207
Metadata
- Authors
- Le Couteur, A., Bailey, A., Goode, S., Pickles, A., Gottesman, I., Robertson, S., & Rutter, M.
- Venue
- Journal of Child Psychology and Psychiatry
- Publisher
- Wiley
- Published
- 1996-10
- Volume
- 37
- Issue
- 7
- Pages
- 785-801
- ISSN
- 0021-9630 (ISSN-L)
- 1469-7610
- OpenAlex
- W2067996390
- Cited by
- 442
- References
- 7
- FWCI
- 9.60
- Type
- journal article
- Language
- en
- Open access
- closed
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- Le Couteur, A., Bailey, A., Goode, S., Pickles, A., Gottesman, I., Robertson, S., & Rutter, M. (1996). A Broader Phenotype of Autism: The Clinical Spectrum in Twins. Journal of Child Psychology and Psychiatry. https://doi.org/10.1111/j.1469-7610.1996.tb01475.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
