Lumbar Subarachnoid Infusion Test in Paediatric Neurosurgery
Abstract
SUMMARY Cerebrospinal fluid (CSF) absorption was studied in 59 children by the lumbar subarachnoid constant infusion manometric test. The patients were divided into three groups on the basis of the clinical and neuroradiological findings: hydrocephalus (28 cases), cerebral atrophy (21 cases) and craniosynostosis and microcephaly (10 cases). Results suggesting severe impairment in CSF absorption were obtained in all the children with hydrocephalus under tension. Conversely, the test was normal in all children with cerebral atrophy, and in postoperative tests on hydrocephalic children whose CSF shunts were functioning satisfactorily. A moderate deficit in CSF absorption was demonstrated by some hydrocephalic children, namely those with a slowly progressive ventricular dilatation. Defective CSF absorption in the low‐pressure range but normal in the high ranges was found in children with multiple suture craniosynostosis. RÉSUMÉ Le test de perfusion lombaire sous arachnoidienne en pratique pédiatrique neurochirurgicale L'absorption du liquide céphalorachidien (LCR) a étéétudiée chez 59 enfants par le test manométrique de perfusion permanente lombaire sous arachnoidienne. Les sujets ont été divisés en trois principaux groupes sur la base des données cliniques et neuroradiologiques; hydrocephalic (28 cas), atrophie cerebrale (21 cas) et craniosténose et microcéphalie (10 cas). Les résultats suggèrant une altération grave de l'absorption du LCR ont été obtenus chez tous les enfants avec hydrocéphalic hypertensive; inversement, le test a été normal chez tous les enfants avec atrophie cérébrale et les hydrocéphales opérés avec un fonctionne‐ment satisfaisant du shunt. Un déficit modéré de l'absorption du LCR a été mis en évidence chez quelques hydrocéphales notamment ceux qui présentaient une dilatation ven‐triculaire lentement progressive. Une absorption de LCR, déficient au niveau des basses pressions et normale dans les hautes pressions, a été trouvée chez les enfants a craniosynostoses sur de nombreuses sutures. ZUSAMMENFASSUNG Infusionstest in den lumbalen Subarachnoidalraum in der pädiatrisch‐neurochirurgischen Praxis Bei 59 Kindern wurde die liquorabsorption durch eine kontinuierliche Infusion in den lumbalen Subarachnoidalraum unter gleichzeitiger Druckmessung untersucht. Die Patienten wurden aufgrund der klinischen und neuroradiologischen Befunde in drei Hauptgruppen eingeteilt: Hydrocephalus (28 Patienten); cerebrale Atrophie (21 Patient‐en); und Nahtsynostose und Mikrocephalie (10 Patienten). Die Ergebnisse von alien Kindern mit hypertonem Hydrocephalus weisen auf eine schwere Stöning der Liquorabsorption hin; dagegen waren die Untersuchungen bei alien Kindern mit cerebraler Atrophie und bei hydrocephalen Patienten mit ausreichend funktionierendem Shunt normal. Bei einigen hydrocephalen Kindern, besonders bei denen mit einer langsam progressiven Ventrikelvergrösserung, Hess sich eine leichte Einschränkung der Liquorabsorption nachweisen. Bei den Kindern mit kombinierter Nahtsynostose war die Liquorabsorption im unteren Druckbereich eingeschränkt und im oberen Druckbereich normal.
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Impaired CSF resorption in children with ISS has been demonstrated by infusion into the lumbar subarachnoid space; these studies also showed decompression of the sagittal sinus after surgery, improved CSF reabsorption, and reduced subarachnoid CSF collections.
“In the past, impaired CSF resorption in children with ISS has also been demonstrated by the technique of infusion into the lumbar subarachnoid space [15,16]. These studies have also shown a decompression of the sagittal sinus after surgery. This improved CSF reabsorption and reduced the extent of subarachnoid CSF collections.”
From Isolated Sagittal Craniosynostosis: A Comprehensive Review (2024) · cites this paper as [15]
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Isolated Sagittal Craniosynostosis: A Comprehensive Review
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- Authors
- Caldarelli, M., Rocco, C. D., & Rossi, G. F.
- Affiliations
- Università Cattolica del Sacro Cuore (IT)
- Corresponding author
- Rocco, Concezio Di
- ORCID
- Caldarelli, Massimo
- Venue
- Developmental Medicine & Child Neurology
- Publisher
- Wiley
- Published
- 1979-02
- Volume
- 21
- Issue
- 1
- Pages
- 71-82
- ISSN
- 0012-1622 (ISSN-L)
- 1469-8749
- OpenAlex
- W1985592597
- Cited by
- 23
- References
- 19
- Citations by year
- 2025: 1 · 2024: 3 · 2022: 1 · 2020: 1 · 2019: 2 · 2012: 1
- FWCI
- 0.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Developmental Medicine & Child Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Cerebrospinal fluid and hydrocephalus
- Health Sciences › Medicine › Neurology › Neurosurgical Procedures and Complications
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Spinal Dysraphism and Malformations
- Keywords
- cerebrospinal fluid absorption, hydrocephalus, brain atrophy, craniosynostosis, microcephaly, cerebrospinal fluid shunt, ventriculomegaly, children, pediatric neurosurgery, cerebrospinal fluid pressure
- MeSH terms
- Adolescent, Atrophy, Brain Diseases, Cerebrospinal Fluid Shunts, Child, Child, Preschool, Craniosynostoses, Female, Humans, Hydrocephalus, Infant, Injections, Intracranial Pressure, Lumbosacral Region, Male, Microcephaly, Sodium Chloride, Subarachnoid Space
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