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Doppler ultrasound assessment of cerebral blood flow in the human fetus
Abstract
Summary. A mechanical sector and linear array real‐time scanner combined with a pulsed Doppler system was used for recording the flow velocity waveform in the internal carotid artery, the lower thoracic part of the descending aorta and umbilical artery in the human fetus. A total of 42 fetuses in normal pregnancy and nine growth‐retarded fetuses between 26 and 41 weeks gestation was studied. In normal pregnancy the mean pulsatility index (PI) in the internal carotid artery varied between 1·5 and 1·6, in the descending aorta between 1·7 and 1·8 and in the umbilical artery between 0·7 and 1·3. In the growth‐retarded fetuses the PI was reduced in the internal carotid artery and raised in the descending aorta and umbilical artery, suggesting an increased peripheral vascular resistance in the fetal body and placenta and a compensatory reduction in peripheral vascular resistance in the fetal cerebrum, i.e. a brain‐sparing effect in the presence of fetal hypoxia.
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Citations
Cited by
Hong, G., Zou, Y., Antaris, A. L., Diao, S., Wu, D., Cheng, K., Zhang, X., Chen, C., Liu, B., He, Y., et al. (2014) · Nature Communications · doi:10.1038/ncomms5206 · Cited by 563
Sun, L., Macgowan, C. K., Sled, J. G., Yoo, S.-J., Manlhiot, C., Porayette, P., Grosse-Wortmann, L., Jaeggi, E., McCrindle, B. W., Kingdom, J., et al. (2015) · Circulation · doi:10.1161/circulationaha.114.013051 · Cited by 533
Clinical significance of absent or reversed end diastolic velocity waveforms in umbilical artery
Karsdorp, V. H. M., van Vugt, J. M. G., van Geijn, H. P., Kostense, P. J., Arduim, D., Montenegro, N., & Todros, T. (1994) · The Lancet · doi:10.1016/s0140-6736(94)90457-x · Cited by 445
Baschat, A. A., Gembruch, U., & Harman, C. R. (2001) · Ultrasound in Obstetrics & Gynecology · doi:10.1046/j.0960-7692.2001.00591.x · Cited by 435
Progression of Doppler abnormalities in intrauterine growth restriction
Turan, O. M., Turan, S., Gungor, S., Berg, C., Moyano, D., Gembruch, U., Nicolaides, K. H., Harman, C. R., & Baschat, A. A. (2008) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.5386 · Cited by 353
Metadata
- Authors
- WLADIMIROFF, J. W., TONGE, H. M., & STEWART, P. A.
- Venue
- BJOG: An International Journal of Obstetrics & Gynaecology
- Publisher
- Wiley
- Published
- 1986-04
- Volume
- 93
- Issue
- 4
- Pages
- 471-475
- ISSN
- 0306-5456 (ISSN-L)
- 1470-0328
- 1471-0528
- OpenAlex
- W2047985903
- Cited by
- 474
- References
- 0
- FWCI
- 42.51
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Doppler ultrasound assessment of cerebral blood flow in the human fetus. https://app.cochat.ai/papers/10.1111/j.1471-0528.1986.tb07932.x
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- WLADIMIROFF, J. W., TONGE, H. M., & STEWART, P. A. (1986). Doppler ultrasound assessment of cerebral blood flow in the human fetus. BJOG: An International Journal of Obstetrics & Gynaecology. https://doi.org/10.1111/j.1471-0528.1986.tb07932.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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