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Cited by 465

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

A RADIOISOTOPIC METHOD FOR MEASURING THE FORMATION OF ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE IN INCUBATED SLICES OF BRAIN

Shimizu, H., Daly, J. W., Creveling, C. R.·1969·Journal of Neurochemistry

Abstract

Abstract— A simple and sensitive method for measuring the effect of neurohormones and other chemical agents on the formation of adenosine 3′,5′‐cyclic monophosphate (cyclic 3′,5′‐AMP) in incubated slices of brain was developed. The principle of the method depends on pulse‐labelling of adenosine‐5′‐triphosphate in slices of brain with [8‐14 C]adenine, followed by incubation in a medium containing the test substance, separation by thin‐layer chromatography of the cyclic nucleotide formed in the slices, and radioassay. The purity of the cyclic nucleotide was confirmed by chromatography in a variety of systems and by hydrolysis with a specific, bovine‐heart phosphodiesterase. The method was used to study the effect of histamine, norepinephrine, and adenosine on the accumulation of adenosine 3′,5′‐cyclic monophosphate in incubated slices of brain.

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Crossref · 10.1111/j.1471-4159.1969.tb10360.x

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Metadata

Authors
Shimizu, H., Daly, J. W., & Creveling, C. R.
Venue
Journal of Neurochemistry
Publisher
Wiley
Published
1969-12
Volume
16
Issue
12
Pages
1609-1619
ISSN
  • 0022-3042 (ISSN-L)
  • 1471-4159
OpenAlex
W1987346819
Cited by
465
References
8
FWCI
10.17
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A RADIOISOTOPIC METHOD FOR MEASURING THE FORMATION OF ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE IN INCUBATED SLICES OF BRAIN. https://app.cochat.ai/papers/10.1111/j.1471-4159.1969.tb10360.x
The paper
Shimizu, H., Daly, J. W., & Creveling, C. R. (1969). A RADIOISOTOPIC METHOD FOR MEASURING THE FORMATION OF ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE IN INCUBATED SLICES OF BRAIN. Journal of Neurochemistry. https://doi.org/10.1111/j.1471-4159.1969.tb10360.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.