Muscle strength in hyperthyroid patients before and after medical treatment
Abstract
Ten hyperthyroid patients were assessed for muscle strength before and after a period of medical treatment that averaged 12 months. The subjects did not change their habitual level of physical activity between the two test occasions. Maximal voluntary isokinetic knee extensor muscle strength was determined during various concentric, eccentric and isometric conditions. Average increases in strength from before to termination of treatment ranged from 25 to 41% for the concentric and isometric tests (P less than 0.01, n = 10), and from 19 to 35% for the eccentric tests (P less than 0.01, n = 6). The present study demonstrates that medical treatment of hyperthyroid patients results in a marked increase in muscle strength.
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In young or non-elderly subjects, hyperthyroidism is associated with reduced muscle strength.
“few studies in young or non-elderly subjects have demonstrated reduced muscle strength, which is restored after normalization of thyroid hormones (114–119).”
From Levothyroxine therapy in elderly patients with hypothyroidism (2021) · cites this paper as [114]
Muscle strength is restored after normalization of thyroid hormones in young or non-elderly subjects with hyperthyroidism.
“few studies in young or non-elderly subjects have demonstrated reduced muscle strength, which is restored after normalization of thyroid hormones (114–119).”
From Levothyroxine therapy in elderly patients with hypothyroidism (2021) · cites this paper as [114]
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- Authors
- Celsing, F., Westing, S. H., Adamson, U., & Ekblom, B.
- Affiliations
- Karolinska Institutet (SE)
- Danderyds sjukhus (SE)
- Corresponding author
- Celsing, F.
- ORCID
- Ekblom, B.
- Venue
- Clinical Physiology
- Publisher
- Wiley
- Published
- 1990-11
- Volume
- 10
- Issue
- 6
- Pages
- 545-550
- ISSN
- 0144-5979 (ISSN-L)
- 1365-2281
- OpenAlex
- W2088950296
- Cited by
- 14
- References
- 12
- Citations by year
- 2021: 1 · 2020: 2 · 2019: 1 · 2018: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Physiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Karolinska Institutet
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
- Keywords
- hyperthyroidism, muscle strength, medical treatment, isometric strength, physical activity
- MeSH terms
- Adult, Analysis of Variance, Body Weight, Female, Humans, Hyperthyroidism, Male, Methimazole, Muscles, Propranolol, Thiouracil
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