Cited by 400Community Health and DevelopmentEthics in Clinical ResearchHealth disparities and outcomes

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A Systematic Review of Community‐Based Participatory Research to Enhance Clinical Trials in Racial and Ethnic Minority Groups

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De Las Nueces, Denise, Hacker, Karen, DiGirolamo, Ann, Hicks, LeRoi S.·2012·Health Services Research

DOI 10.1111/j.1475-6773.2012.01386.xPMC PMC3418827

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Abstract

Objective: To examine the effectiveness of current community‐based participatory research (CBPR) clinical trials involving racial and ethnic minorities. Data Source: All published peer‐reviewed CBPR intervention articles in PubMed and CINAHL databases from January 2003 to May 2010. Study Design: We performed a systematic literature review. Data Collection/Extraction Methods: Data were extracted on each study's characteristics, community involvement in research, subject recruitment and retention, and intervention effects. Principle Findings: We found 19 articles meeting inclusion criteria. Of these, 14 were published from 2007 to 2010. Articles described some measures of community participation in research with great variability. Although CBPR trials examined a wide range of behavioral and clinical outcomes, such trials had very high success rates in recruiting and retaining minority participants and achieving significant intervention effects. Conclusions: Significant publication gaps remain between CBPR and other interventional research methods. CBPR may be effective in increasing participation of racial and ethnic minority subjects in research and may be a powerful tool in testing the generalizability of effective interventions among these populations. CBPR holds promise as an approach that may contribute greatly to the study of health care delivery to disadvantaged populations.

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Authors: De Las Nueces, D., Hacker, K., DiGirolamo, A., & Hicks, L. S.
Affiliations: Office of Diversity and Community Partnership Harvard Medical School Boston MA
Cambridge Health Alliance (US)
CARE USA (US)
UMass Memorial Health Care (US)
ORCID: Hacker, Karen
DiGirolamo, Ann
Venue: Health Services Research
Publisher: Wiley
Published: 2012-02-21
Volume: 47
Issue: 3pt2
Pages: 1363-1386
ISSN: 0017-9124 (ISSN-L)
1475-6773
DOI: 10.1111/j.1475-6773.2012.01386.x
PMC: PMC3418827
OpenAlex: W2107954772
Cited by: 400
References: 33
Citations by year: 2026: 15 · 2025: 26 · 2024: 37 · 2023: 29 · 2022: 41 · 2021: 34 · 2020: 31 · 2019: 32 · 2018: 25 · 2017: 48 · 2016: 21 · 2015: 16 · 2014: 29 · 2013: 11 · 2012: 3
FWCI: 2.83
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Health Services Research (publishedVersion)
PubMed Central (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Community Health and Development
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
Social Sciences › Health › Health disparities and outcomes
Keywords: community-based participatory research, racial and ethnic minorities, clinical trials, minority participation in research, participant recruitment, participant retention, community-engaged research, intervention effectiveness
MeSH terms: Clinical Trials as Topic, Ethnicity, Humans, Outcome and Process Assessment, Health Care, Research Design, Health Behavior, Racial Groups, Community-Based Participatory Research

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A Systematic Review of Community‐Based Participatory Research to Enhance Clinical Trials in Racial and Ethnic Minority Groups

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