The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE
Open accessAbstract
A method has been described for the study of the central effects produced by the intracerebral injection of drugs in the unanaesthetized mouse. The effects observed were in good agreement with those obtained after similar injections in cats, dogs and human beings. After intracerebral injection, drugs of diverse structure produced certain generalized effects: changes in positioning of the tail, stupor, hyperexcitability and tachypnoea. Both acetylcholine and methacholine produced an akinetic seizure and depression, but the latter compound also caused lacrimation and salivation. Atropine produced piloerection, increased sensitivity to sound and touch, clonic convulsions and scratching, whereas hexamethonium caused Parkinsonian‐like muscle tremors and peripheral vasodilatation. After adrenaline, hyperexcitability, exophthalmos, stupor and death from pulmonary oedema were observed, but (+)‐methylamphetamine produced only piloerection and exaggerated activity in response to sound and touch. Ergotamine caused a decreased sensitivity to sound and touch, micturition, and stupor, while ergometrine caused clonic convulsions, piloerection, defaecation and stupor.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Pharmacological. Basis of Therapeutics
Lee, L. E. (1955) · American Journal of Clinical Pathology · doi:10.1093/ajcp/25.12.1401a · Cited by 532
Cited by
Campfield, L. A., Smith, F. J., Guisez, Y., Devos, R., & Burn, P. (1995) · Science · doi:10.1126/science.7624778 · Cited by 3,243
A potent and selective endogenous agonist for the µ-opiate receptor
Zadina, J. E., Hackler, L., Ge, L.-J., & Kastin, A. J. (1997) · Nature · doi:10.1038/386499a0 · Cited by 1,311
Maurice, T., Lockhart, B. P., & Privat, A. (1996) · Brain Research · doi:10.1016/0006-8993(95)01032-7 · Cited by 521
The Molecular and Behavioral Pharmacology of the Orphanin FQ/Nociceptin Peptide and Receptor Family
Mogil, J. S., & Pasternak, G. W. (2001) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01502-3 · Cited by 441
Itoh, J., Nabeshima, T., & Kameyama, T. (1990) · Psychopharmacology · doi:10.1007/bf02253713 · Cited by 411
Metadata
- Authors
- HALEY, T. J., & McCORMICK, W. G.
- Venue
- British Journal of Pharmacology and Chemotherapy
- Publisher
- Wiley
- Published
- 1957-03
- Volume
- 12
- Issue
- 1
- Pages
- 12-15
- ISSN
- 0366-0826 (ISSN-L)
- OpenAlex
- W2088637181
- Cited by
- 1,526
- References
- 1
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE. https://app.cochat.ai/papers/10.1111/j.1476-5381.1957.tb01354.x
- The paper
- HALEY, T. J., & McCORMICK, W. G. (1957). PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE. British Journal of Pharmacology and Chemotherapy. https://doi.org/10.1111/j.1476-5381.1957.tb01354.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
