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RECEPTORS MEDIATING SOME ACTIONS OF HISTAMINE
Open accessAbstract
The specific antagonism of some actions of histamine by low concentrations of anti- histamine drugs characterizes one type of histamine receptor for which we suggest the symbol H.Such receptors occur in guinea-pig ileum and bronchi (Arunlakshana & Schild, 1959).Several other actions of histamine, for example, stimulation of gastric acid secretion, inhibition of rat uterus and stimulation of isolated atria, cannot be specifically antagonized (Loew, 1947; Ashford, Heller & Smart, 1949; Dutta, 1949; Trendelenburg, 1960).These actions are likely to be mediated by other histamine receptors.The effects of many compounds related to histamine have previously been examined on the isolated ileum and uterus of the guinea-pig and the blood pressure of the cat (Dale & Dudley, 1921 ; Vartiainen, 1935 ;
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Cited by
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Bousquet, J., van Cauwenberge, P., & Khaltaev, N. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.118891 · Cited by 3,588
Histamine, histamine receptors and their role in immune pathology
Jutel, M., Akdis, M., & Akdis, C. A. (2009) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2009.03374.x · Cited by 329
Regulation of the immune response and inflammation by histamine and histamine receptors
O’Mahony, L., Akdis, M., & Akdis, C. A. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.06.051 · Cited by 313
Second-Generation Antihistamines: Actions and Efficacy in the Management of Allergic Disorders
Golightly, L. K., & Greos, L. S. (2005) · Drugs · doi:10.2165/00003495-200565030-00004 · Cited by 111
The effect of H1 and H2 blockade on cutaneous histamine response in man
Harvey, R. P., & Schocket, A. L. (1980) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(80)90198-0 · Cited by 86
Metadata
- Authors
- ASH, A. S. F., & SCHILD, H. O.
- Venue
- British Journal of Pharmacology and Chemotherapy
- Publisher
- Wiley
- Published
- 1966-08
- Volume
- 27
- Issue
- 2
- Pages
- 427-439
- ISSN
- 0366-0826 (ISSN-L)
- OpenAlex
- W2117833280
- Cited by
- 758
- References
- 0
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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- ASH, A. S. F., & SCHILD, H. O. (1966). RECEPTORS MEDIATING SOME ACTIONS OF HISTAMINE. British Journal of Pharmacology and Chemotherapy. https://doi.org/10.1111/j.1476-5381.1966.tb01674.x
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