The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Evidence for a central 5‐hydroxytryptamine receptor stimulation by lysergic acid diethylamide
Open accessAbstract
Lysergic acid diethylamide (LSD) and the 5‐hydroxytryptamine (5‐HT) precursor, 5‐hydroxytryptophan produced similar functional effects in rat spinal cord and brain to the 5‐hydroxytryptamine precursor 5‐hydroxytryptophan, which indicates that LSD stimulates central 5‐HT receptors. By means of combined histochemical and biochemical techniques it was found that LSD reduced the turnover rate of brain and spinal cord 5‐HT, studied after inhibition of the tryptophan hydroxylase by α‐propyldopacet‐amide. The turnover of brain noradrenaline but not dopamine was somewhat accelerated. The functional and chemical effects by LSD were related to dose and to time. They were not observed after the LSD analogues 2‐bromo‐LSD and methysergide. The retardation of the 5‐HT turnover by LSD may be due to negative feed‐back mechanisms evoked by direct stimulation of the central 5‐HT receptors.
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FLUORESCENCE OF CATECHOL AMINES AND RELATED COMPOUNDS CONDENSED WITH FORMALDEHYDE
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Spector, S., Sjoerdsma, A., & Udenfriend, S. (1965) · PubMed · Cited by 812
CORRODI, H., & JONSSON, G. (1967) · Journal of Histochemistry & Cytochemistry · doi:10.1177/15.2.65 · Cited by 786
Self-citationA Fluorimetric Method for the Determination of Dopamine (3‐Hydroxytyramine.)
CARLSSON, A., & WALDECK, B. (1958) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1958.tb01628.x · Cited by 625
In‐Vivo Decarboxylation of α‐Methyl DOPA and α‐Methyl Metatyrosine
Carlsson, A., & Lindqvist, M. (1962) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1962.tb02331.x · Cited by 529
Central effects of an inhibitor of tyrosine hydroxylation
Corrodi, H., & Hanson, L. C. F. (1966) · Psychopharmacologia · doi:10.1007/bf00455973 · Cited by 220
Self-citationEffects of tyrosine hydroxylase inhibition on the amine levels of central monoamine neurons
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Self-citationSpector, S., Sjoerdsma, A., & Udenfriend, S. (1965) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)26954-3 · Cited by 195
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Cited by
Nichols, D. E. (2016) · Pharmacological Reviews · doi:10.1124/pr.115.011478 · Cited by 1,762
Nichols, D. E. (2004) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2003.11.002 · Cited by 1,211
Drug‐Induced Changes in the Release of3H‐Monoamines from Field Stimulated Rat Brain Slices
Farnebo, L., & Hamberger, B. (1971) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1971.tb05213.x · Cited by 451
Morphological and Functional Aspects of Central Monoamine Neurons
(1970) · International Review of Neurobiology · doi:10.1016/s0074-7742(08)60167-1 · Cited by 352
Drew, G. M. (1976) · European Journal of Pharmacology · doi:10.1016/0014-2999(76)90084-4 · Cited by 289
Metadata
- Authors
- ANDÉN, N. ‐., CORRODI, H., FUXE, K., & HÖKFELT, T.
- Venue
- British Journal of Pharmacology
- Publisher
- Wiley
- Published
- 1968-09
- Volume
- 34
- Issue
- 1
- Pages
- 1-7
- ISSN
- 0007-1188 (ISSN-L)
- 1476-5381
- OpenAlex
- W1997714022
- Cited by
- 273
- References
- 14
- FWCI
- 9.64
- Type
- journal article
- Language
- en
- Open access
- green
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- ANDÉN, N. ‐., CORRODI, H., FUXE, K., & HÖKFELT, T. (1968). Evidence for a central 5‐hydroxytryptamine receptor stimulation by lysergic acid diethylamide. British Journal of Pharmacology. https://doi.org/10.1111/j.1476-5381.1968.tb07943.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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