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THE FORMALDEHYDE FLUORESCENCE METHOD FOR THE HISTOCHEMICAL DEMONSTRATION OF BIOGENIC MONOAMINES A REVIEW ON THE METHODOLOGY
Open accessAbstract
The histochemical fluorescence method of Falck and Hillarp for the demonstration of biogenic monoamines is based on the finding that the amines can be condensed with formaldehyde to yield strongly fluorescent compounds, provided that they are enclosed in a dried protein layer, as in freeze-dried or air-dried tissues. This review deals mainly with certain principal features of the method: its chemistry, sensitivity, specificity and possibilities for histochemical differentiation between the various amines. Some comments are made on certain of the results obtained with this method.
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Citations
Cited by
Stereotaxic mapping of the monoamine pathways in the rat brain
Ungerstedt, U. (1971) · Acta Physiologica Scandinavica · doi:10.1111/j.1365-201x.1971.tb10998.x · Cited by 3,819
Ungerstedt, U. (1971) · Acta Physiologica Scandinavica · doi:10.1111/j.1365-201x.1971.tb11000.x · Cited by 1,922
In vitro studies on central and peripheral monoamine neurons at the ultrastructural level
H�kfelt, T. (1968) · Zeitschrift f�r Zellforschung und Mikroskopische Anatomie · doi:10.1007/bf00336984 · Cited by 499
On the projections from the locus coeruleus noradrenaline neurons: The cerebellar innervation
Olson, L., & Fuxe, K. (1971) · Brain Research · doi:10.1016/0006-8993(71)90533-6 · Cited by 494
Alkaloids from Catecholamines in Adrenal Tissue: Possible Role in Alcoholism
Cohen, G., & Collins, M. (1970) · Science · doi:10.1126/science.167.3926.1749 · Cited by 438
Metadata
- Authors
- CORRODI, H., & JONSSON, G.
- Venue
- Journal of Histochemistry & Cytochemistry
- Publisher
- SAGE Publications
- Published
- 1967-02
- Volume
- 15
- Issue
- 2
- Pages
- 65-78
- ISSN
- 0022-1554 (ISSN-L)
- 1551-5044
- OpenAlex
- W2073997713
- Cited by
- 786
- References
- 0
- FWCI
- 107.44
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: THE FORMALDEHYDE FLUORESCENCE METHOD FOR THE HISTOCHEMICAL DEMONSTRATION OF BIOGENIC MONOAMINES A REVIEW ON THE METHODOLOGY. https://app.cochat.ai/papers/10.1177/15.2.65
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- CORRODI, H., & JONSSON, G. (1967). THE FORMALDEHYDE FLUORESCENCE METHOD FOR THE HISTOCHEMICAL DEMONSTRATION OF BIOGENIC MONOAMINES A REVIEW ON THE METHODOLOGY. Journal of Histochemistry & Cytochemistry. https://doi.org/10.1177/15.2.65
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
