The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Time‐dose relationships for locomotor activity effects of morphine after acute or repeated treatment
Open accessAbstract
Summary: . Effects of morphine sulphate (1·25, 2·5, 5, 10, 20 and 40 mg/kg i.p.) on locomotor activity of male rats were observed for 8 h after single doses in non‐tolerant rats. The lower three doses had only an excitatory effect, whereas the higher three doses caused initial depression followed by a delayed excitatory effect. . The same doses of morphine were administered daily for 30 days. No tolerance developed within this time to the excitatory effect. The locomotor excitatory effect of the higher three doses of morphine became progressively more pronounced over treatment periods of 30 days (and 48 days for 20 mg/kg), while the latency to peak activity decreased. . An explanation of these results is suggested on the basis of two different central drug‐receptor interactions affecting motility.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Distribution of the Ratio of the Mean Square Successive Difference to the Variance
von Neumann, J. (1941) · The Annals of Mathematical Statistics · doi:10.1214/aoms/1177731677 · Cited by 932
Tolerance to and physical dependence on morphine in rats
Martin, W. R., Wikler, A., Eades, C. G., & Pescor, F. T. (1963) · Psychopharmacologia · doi:10.1007/bf00408180 · Cited by 446
Behavioural effects in rats of morphine and amphetamine and of a combination of the two drugs
Fog, R. (1970) · Psychopharmacologia · doi:10.1007/bf00404736 · Cited by 167
MORPHINE ADDICTION AND ITS PHYSIOLOGICAL INTERPRETATION BASED ON EXPERIMENTAL EVIDENCES
Tatum, A. L., Seevers, M. H., & COLLINS, K. H. (1929) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)04096-0 · Cited by 120
Catecholamines and 5-hydroxytryptamine in morphine tolerance and withdrawal.
Gunne, L. M. (1963) · PubMed · Cited by 120
Disturbed patterns of behaviour in morphine tolerant and abstinent rats
Kumar, R. C., MITCHELL, E., & Stolerman, I. P. (1971) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1971.tb07132.x · Cited by 115
MORPHINE-INDUCED HYPERALGESIA IN RATS TESTED ON THE HOT PLATE
Kayan, S., Woods, L. A., & Mitchell, C. L. (1971) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)28909-1 · Cited by 69
A SIMPLE METHOD FOR PRODUCING TOLERANCE TO DIHYDROMORPHINONE IN MICE
Shuster, L., Hannam, R. V., & Boyle, W. E. (1963) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)26531-4 · Cited by 50
Cited by
The neural basis of drug craving: An incentive-sensitization theory of addiction
Robinson, T. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90013-p · Cited by 7,346
ROBINSON, T., & BECKER, J. (1986) · Brain Research · doi:10.1016/s0006-8993(86)80193-7 · Cited by 2,106
Robinson, T. E., & Becker, J. B. (1986) · Brain Research Reviews · doi:10.1016/0165-0173(86)90002-0 · Cited by 1,796
Le Bars, D., Gozariu, M., & Cadden, S. W. (2001) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01514-x · Cited by 1,459
Are adolescents more vulnerable to drug addiction than adults? Evidence from animal models
Schramm-Sapyta, N. L., Walker, Q. D., Caster, J. M., Levin, E. D., & Kuhn, C. M. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1585-5 · Cited by 215
Metadata
- Authors
- BABBINI, M., & DAVIS, W. M.
- Venue
- British Journal of Pharmacology
- Publisher
- Wiley
- Published
- 1972-10
- Volume
- 46
- Issue
- 2
- Pages
- 213-224
- ISSN
- 0007-1188 (ISSN-L)
- 1476-5381
- OpenAlex
- W2048538659
- Cited by
- 441
- References
- 8
- FWCI
- 1.51
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Time‐dose relationships for locomotor activity effects of morphine after acute or repeated treatment. https://app.cochat.ai/papers/10.1111/j.1476-5381.1972.tb06866.x
- The paper
- BABBINI, M., & DAVIS, W. M. (1972). Time‐dose relationships for locomotor activity effects of morphine after acute or repeated treatment. British Journal of Pharmacology. https://doi.org/10.1111/j.1476-5381.1972.tb06866.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
