The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
The solute carrier 6 family of transporters
Open accessAbstract
The solute carrier 6 (SLC6) family of the human genome comprises transporters for neurotransmitters, amino acids, osmolytes and energy metabolites. Members of this family play critical roles in neurotransmission, cellular and whole body homeostasis. Malfunction or altered expression of these transporters is associated with a variety of diseases. Pharmacological inhibition of the neurotransmitter transporters in this family is an important strategy in the management of neurological and psychiatric disorders. This review provides an overview of the biochemical and pharmacological properties of the SLC6 family transporters. LINKED ARTICLESBJP published a themed section on Transporters in 2011. To view articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.2011.164.issue‐7/issuetoc
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Guide to receptors and channels (GRAC), 5th edition
Alexander, S., Mathie, A., & Peters, J. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01649_1.x · Cited by 1,947
Risch, N., Herrell, R., Lehner, T., Liang, K.-Y., Eaves, L., Hoh, J., Griem, A., Kovacs, M., Ott, J., & Merikangas, K. R. (2009) · JAMA · doi:10.1001/jama.2009.878 · Cited by 1,655 · cited 1×
“The general significance of the promoter variant (5HTTLPR) has been debated (Munafo et al., 2009; Risch et al., 2009).”
BackgroundThe Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)
Green, A. R., Mechan, A. O., Elliott, J. M., O’Shea, E., & Colado, M. I. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.3.3 · Cited by 1,272
Modafinil: a review of neurochemical actions and effects on cognition
Minzenberg, M. J., & Carter, C. S. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301534 · Cited by 713
Orthostatic Intolerance and Tachycardia Associated with Norepinephrine-Transporter Deficiency
Shannon, J. R., Flattem, N. L., Jordan, J., Jacob, G., Black, B. K., Biaggioni, I., Blakely, R. D., & Robertson, D. (2000) · New England Journal of Medicine · doi:10.1056/nejm200002243420803 · Cited by 594 · cited 3×
“An inactivating mutation in NET is associated with orthostatic intolerance (Shannon et al., 2000; Hahn et al., 2003), and another variant was identified by analysing candidate genes for blood-pressure homeostasis (Halushka et al., 1999).”
BackgroundSerretti, A., Kato, M., De Ronchi, D., & Kinoshita, T. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001926 · Cited by 529
Sutcliffe, J. S., Delahanty, R. J., Prasad, H. C., McCauley, J. L., Han, Q., Jiang, L., Li, C., Folstein, S. E., & Blakely, R. D. (2005) · The American Journal of Human Genetics · doi:10.1086/432648 · Cited by 392
A Double-Blind, Placebo-Controlled Trial of Modafinil for Cocaine Dependence
Dackis, C. A., Kampman, K. M., Lynch, K. G., Pettinati, H. M., & O'Brien, C. P. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300600 · Cited by 391 · cited 1×
“Accordingly, modafinil might also be a promising therapeutic agent for cocaine addiction (Dackis et al., 2005; Hart et al., 2008; Minzenberg and Carter, 2008).”
BackgroundDwoskin, L. P., Rauhut, A. S., King‐Pospisil, K. A., & Bardo, M. T. (2006) · CNS Drug Reviews · doi:10.1111/j.1527-3458.2006.00178.x · Cited by 259
Zhu, C.-B., Carneiro, A. M., Dostmann, W. R., Hewlett, W. A., & Blakely, R. D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m410858200 · Cited by 228
The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression
Kohli, M. A., Lucae, S., Saemann, P. G., Schmidt, M. V., Demirkan, A., Hek, K., Czamara, D., Alexander, M., Salyakina, D., Ripke, S., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.04.005 · Cited by 228
A Comprehensive In Vitro Screening of d-, l- , and dl-threo -Methylphenidate: An Exploratory Study
Markowitz, J. S., DeVane, C. L., Pestreich, L. K., Patrick, K. S., & Muniz, R. (2006) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2006.16.687 · Cited by 109
Parra, L. A., Baust, T., El Mestikawy, S., Quiroz, M., Hoffman, B., Haflett, J. M., Yao, J. K., & Torres, G. E. (2008) · Molecular Pharmacology · doi:10.1124/mol.108.050005 · Cited by 53
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Developmental and epileptic encephalopathies: from genetic heterogeneity to phenotypic continuum
Guerrini, R., Conti, V., Mantegazza, M., Balestrini, S., Galanopoulou, A. S., & Benfenati, F. (2023) · Physiological Reviews · doi:10.1152/physrev.00063.2021 · Cited by 196
El-Hawary, S. S., Sobeh, M., Badr, W. K., Abdelfattah, M. A. O., Ali, Z. Y., El-Tantawy, M. E., Rabeh, M. A., & Wink, M. (2020) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2020.07.003 · Cited by 102
Asjad, H. M. M., Kasture, A., El-Kasaby, A., Sackel, M., Hummel, T., Freissmuth, M., & Sucic, S. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.797092 · Cited by 53
SLC6 Transporter Folding Diseases and Pharmacochaperoning
Freissmuth, M., Stockner, T., & Sucic, S. (2017) · Handbook of experimental pharmacology · doi:10.1007/164_2017_71 · Cited by 42
Presynaptic control of inhibitory neurotransmitter content in VIAAT containing synaptic vesicles
Aubrey, K. R. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.06.002 · Cited by 30
Metadata
- Authors
- Bröer, S., & Gether, U.
- Venue
- British Journal of Pharmacology
- Publisher
- Wiley
- Published
- 2012-08-22
- Volume
- 167
- Issue
- 2
- Pages
- 256-278
- ISSN
- 0007-1188 (ISSN-L)
- 1476-5381
- OpenAlex
- W1908164157
- Cited by
- 269
- References
- 13
- FWCI
- 5.05
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
