Tai Chi exercise versus rehabilitation for the elderly with cerebral vascular disorder: a single-blinded randomized controlled trial: Tai Chi versus rehabilitation
Open accessAbstract
BACKGROUND: Cerebral vascular disorder (CVD) might result in a quantifiable decrease in quality of life, which is determined not only by the neurological deficits but also by impairment of cognitive functions. There are few studies that report on the cognitive effect of Tai Chi exercise (Tai Chi) on the elderly with CVD. The purpose of the present study was to examine the cognitive effect of Tai Chi on the elderly with CVD using P300 measurement, in addition to the General Health Questionnaire (GHQ) and Pittsburgh Sleep Quality Index (PSQI). METHODS: A total of 34 patients with CVD were recruited from outpatient Akistu-Kounoike Hospital and randomly assigned to receive Tai Chi (n= 17) or rehabilitation (n= 17) in group sessions once a week for 12 weeks. To examine the time courses of each score (P300 amplitude, P300 latency, GHQ score and PSQI score), repeated-measures analysis of variance was carried out with groups and time as factors. RESULTS: For the time courses of P300 amplitudes and latencies, there were no significant effects of interaction between group and time. However, significant time-by-group interactions were found for Sleep Quality (P= 0.006), GHQ total score (P= 0.005), anxiety/insomnia score (P= 0.034), and severe depression score (P= 0.020). CONCLUSIONS: Tai Chi might therefore be considered a useful non-pharmacological approach, along with rehabilitation, for the maintenance of cognitive function in the elderly with CVD and might be a more useful non-pharmacological approach for the improvement of sleep quality and depressive symptoms in the elderly with CVD than rehabilitation.
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Several mechanisms provide a rationale for the improvement in insomnia symptoms from exercise, including reducing core body temperature for sleep onset, increasing melatonin and serotonin secretion, reducing depression and anxiety, and improving autonomic regulation which may reduce hyperarousal associated with insomnia.
“Several mechanisms that provide a rationale for the improvement in insomnia symptoms from exercise have been suggested [133,136,137,138,139]; these include but are not limited to reducing core body temperature for sleep onset [140,141,142,143], increasing melatonin and serotonin secretion [131,144], reducing depression and anxiety, and improving autonomic regulation which may reduce hyperarousal”
From The Cyclical Battle of Insomnia and Mental Health Impairment in Firefighters: A Narrative Review (2024) · cites this paper as [136]
The Discussion (pp. 160–166) reports improved sleep quality and depression and anxiety/insomnia scores with Tai Chi in elderly patients with cerebral vascular disorder. It also mentions increased serotonin synthesis and release as a hypothesis requiring biological study. The paper does not support the proposed mechanisms involving reduced core body temperature, melatonin secretion, or autonomic regulation, nor does it establish that the measured symptom improvements were caused by serotonin changes. (LLM, conf=0.87)
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- Authors
- WANG, W., SAWADA, M., NORIYAMA, Y., ARITA, K., OTA, T., SADAMATSU, M., KIYOTOU, R., HIRAI, M., & KISHIMOTO, T.
- Affiliations
- Akitsu Kounoike Hospital (JP)
- Nara Medical University (JP)
- Corresponding author
- SAWADA, Masayuki
- ORCID
- OTA, Toyosaku
- Venue
- Psychogeriatrics
- Publisher
- Wiley
- Published
- 2010-09-22
- Volume
- 10
- Issue
- 3
- Pages
- 160-166
- ISSN
- 1346-3500 (ISSN-L)
- OpenAlex
- W1558733840
- Cited by
- 97
- References
- 20
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 5 · 2023: 3 · 2022: 9 · 2021: 10 · 2020: 6 · 2019: 4 · 2018: 10 · 2017: 7 · 2016: 5 · 2015: 9 · 2014: 6 · 2013: 7 · 2012: 5
- FWCI
- 3.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psychogeriatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Keywords
- Tai Chi, stroke rehabilitation, cognitive function, P300, sleep quality, depression, anxiety, insomnia, older adults, non-pharmacological treatment
- MeSH terms
- Aged, Cerebral Cortex, Cognition Disorders, Electroencephalography, Female, Health Status, Humans, Sleep Initiation and Maintenance Disorders, Male, Pilot Projects, Quality of Life, Reaction Time, Signal Processing, Computer-Assisted, Dementia, Vascular, Single-Blind Method, Walking, Event-Related Potentials, P300, Tai Ji, Resistance Training
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