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Cited by 288

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Bone marrow‐derived stem cells in wound healing: a review

Wu, Yaojiong, Wang, JianFei, Scott, Paul G., Tredget, Edward E.·2007·Wound Repair and Regeneration

Abstract

Optimum healing of a cutaneous wound requires a well‐orchestrated integration of the complex biological and molecular events of cell migration and proliferation, and of extracellular matrix deposition and remodeling. Several studies in recent years suggest that bone marrow derived stem cells such as mesenchymal stem cells, progenitor cells such as endothelial progenitor cells and fibrocytes may be involved in these processes, contributing to skin cells or releasing regulatory cytokines. Stem/progenitor cells may be mobilized to leave the bone marrow, home to injured tissues and participate in the repair and regeneration. Direct injection of bone marrow derived mesenchymal stem cells or endothelial progenitor cells into injured tissues shows improved repair through mechanisms of differentiation and/or release of paracrine factors. Enhanced understanding of these cells may help develop novel therapies for difficult cutaneous conditions such as non‐healing chronic wounds and hypertrophic scarring as well as engineering cutaneous substitutes.

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Crossref · 10.1111/j.1524-475x.2007.00221.x

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Metadata

Authors
Wu, Y., Wang, J., Scott, P. G., & Tredget, E. E.
Venue
Wound Repair and Regeneration
Publisher
Wiley
Published
2007-08-21
Volume
15
Issue
s1
Pages
S18-26
ISSN
  • 1067-1927 (ISSN-L)
  • 1524-475X
OpenAlex
W2074445743
Cited by
288
References
1
FWCI
14.52
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Bone marrow‐derived stem cells in wound healing: a review. https://app.cochat.ai/papers/10.1111/j.1524-475x.2007.00221.x
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Wu, Y., Wang, J., Scott, P. G., & Tredget, E. E. (2007). Bone marrow‐derived stem cells in wound healing: a review. Wound Repair and Regeneration. https://doi.org/10.1111/j.1524-475x.2007.00221.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.