Port-site metastases after open laparoscopy: A study in 173 patients with advanced ovarian carcinoma
Open accessAbstract
Open laparoscopy was used to diagnose advanced ovarian cancer. Patients with a pelvic mass and an omental cake and/or large-volume ascites were selected for open laparoscopy. One hundred and seventy-three patients with stage III or IV ovarian carcinoma underwent diagnostic open laparoscopy. Seventy-one patients underwent complete excision of port sites at the time of debulking surgery. Thirty (17%) patients developed port-site metastases. However, only 8 (5%) of these port-site metastases were clinically diagnosed, while 22 out of 71 (31%) with complete port-site excision were diagnosed on pathologic examination. There was no significant relationship between the development of port-site metastases and median time to primary chemotherapy or surgery, the presence of ascites, or stage IV disease. All port-site metastases disappeared during primary therapy, and none of the patients developed a second relapse in one of their port sites. We observed a high rate of port-site metastases after laparoscopy in patients with advanced ovarian carcinoma. However, prognosis was not worse in this group of patients. Laparoscopy is a convenient technique to diagnose advanced ovarian carcinoma, to exclude other primary tumors, and to refer patients to a tertiary center.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Ovarian and/or pelvic endometriosis is associated with approximately 42% of endometrioid ovarian cancer.
“Ovarian and/or pelvic endometriosis is associated with approximately 42% of endometrioid ovarian cancer [18,19,20,21].”
From Malignancy in Abdominal Wall Endometriosis: Is There a Way to Avoid It? A Systematic Review (2024) · cites this paper as [19]
Vergotte et al. (2005) reported a high incidence of metastasis at the port site after diagnostic laparoscopies in advanced stages of ovarian cancer, despite precautionary measures.
“Vergotte et al. (2005) reported a high incidence of metastasis at the port site, despite precautionary measures [19].”
From Malignancy in Abdominal Wall Endometriosis: Is There a Way to Avoid It? A Systematic Review (2024) · cites this paper as [19]
Cites
van der Burg, M. E. L., van Lent, M., Buyse, M. E., Kobierska, A., Colombo, N., Favalli, G., Lacave, Á. J., Nardi, M., Renard, J., & Pecorelli, S. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503093321002 · Cited by 707 · see citing works
van der Burg, M. E. L., van Lent, M., Buyse, M. E., et al. (1995) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-199507000-00012 · Cited by 578 · see citing works
Vergote, I. B., Wever, I. D., Tjalma, W. A. A., et al. (1998) · Gynecologic Oncology · doi:10.1006/gyno.1998.5213 · Cited by 394 · see citing works
Self-citationNelson, B. E., Rosenfield, A. T., & Schwartz, P. E. (1993) · Journal of Clinical Oncology · doi:10.1200/jco.1993.11.1.166 · Cited by 261 · see citing works
Clinical and histologic studies of ovarian carcinoma. Long-term follow-up of 990 cases.
Aure, J. C., Høeg, K., & Kolstad, P. (1971) · PubMed · Cited by 254 · see citing works
Rapid Development of Malignant Metastases in the Abdominal Wall after Laparoscopy
Döbrönte, Z., Wittmann, T., & Karácsony, G. (1978) · Endoscopy · doi:10.1055/s-0028-1098280 · Cited by 199 · see citing works
Intensive Surgical and Chemotherapeutic Management of Advanced Ovarian Cancer
Griffiths, C. T., & Fuller, A. F. (1978) · Surgical Clinics of North America · doi:10.1016/s0039-6109(16)41440-4 · Cited by 193 · see citing works
Laparoscopic port-site metastases: etiology and prevention
Ramirez, P. T., Wolf, J. K., & Levenback, C. (2003) · Gynecologic Oncology · doi:10.1016/s0090-8258(03)00507-9 · Cited by 190 · see citing works
Abdominal‐wall tumor implantation after laparoscopy for malignant conditions
Childers, J. M., Aqua, K. A., Surwit, E. A., Hallum, A. V., & Hatch, K. D. (1995) · International Journal of Gynecology & Obstetrics · doi:10.1016/0020-7292(95)90008-x · Cited by 178 · see citing works
Kruitwagen, R. F. P. M., Swinkels, B. M., Keyser, K. G. G., Doesburg, W. H., & Schijf, C. P. T. (1996) · Gynecologic Oncology · doi:10.1006/gyno.1996.0031 · Cited by 135 · see citing works
van Dam, P. A., Decloedt, J., Tjalma, W. A. A., Buytaert, P., Becquart, D., & Vergote, I. B. (1999) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(99)70489-8 · Cited by 130 · see citing works
Self-citationWang, P., Yuan, C., Lin, G., Ng, H., & Chao, H. (1999) · Gynecologic Oncology · doi:10.1006/gyno.1998.5128 · Cited by 127 · see citing works
Abdominal wall metastasis following laparoscopy: a case report.
Stockdale, A. D., & POCOCK, T. J. (1985) · PubMed · Cited by 96 · see citing works
Jg, H., Given, F. T., & Kemp, G. M. (1986) · PubMed · Cited by 91 · see citing works
Neoadjuvant chemotherapy versus primary debulking surgery in advanced ovarian cancer.
Vergote, I. B., Wever, I. D., Decloedt, J., et al. (2000) · PubMed · Cited by 91 · see citing works
Self-citationDRIESKENS, O., Stroobants, S. G., Gysen, M., et al. (2003) · Gynecologic and Obstetric Investigation · doi:10.1159/000071525 · Cited by 71 · see citing works
Management of port-site metastasis after laparoscopic surgery for ovarian cancer
Huang, K., Wang, C., Chang, T.-C., Liou, J., Hsueh, S., Lai, C., & Huang, L. (2003) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2003.330 · Cited by 56 · see citing works
Wound recurrence by implantation of a borderline ovarian tumour following laparoscopic removal
Shepherd, J. H., Carter, P. G., & Lowe, D. (1994) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1994.tb13128.x · Cited by 53 · see citing works
Gryspeerdt, S. S., Clabout, L., Hoe, L. V., et al. (1998) · PubMed · Cited by 39 · see citing works
Miralles, R. M., Petit, J., Giné, L., & Balagueró, L. F. (1989) · PubMed · Cited by 34 · see citing works
Ovarian cancer presenting in a laparoscopy scar and metastatic to the spleen
Lane, G. K., & Pfau, S. C. (1996) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1996.tb09750.x · Cited by 14 · see citing works
Rieger, N., & McIntosh, N. (1998) · European Journal of Surgical Oncology · doi:10.1016/s0748-7983(98)91641-9 · Cited by 14 · see citing works
[Tumor dissemination after celioscopic treatment of a tumor of the ovary].
Aboujaoudé, I., Leperlier, E., Clough, K. B., et al. (1994) · PubMed · Cited by 12 · see citing works
Implantation metastasis of ovarian cancer after third-look laparoscopy.
Güngör, M., Cengiz, B., Yh, T., et al. (1996) · PubMed · Cited by 7 · see citing works
[Risk of systematic celioscopic treatment of ovarian diseases. 2 cases].
Blanc, B., Nicoloso, E., D’Ercole, C., et al. (1993) · PubMed · Cited by 6 · see citing works
Kontra endoskopische Ovarchirurgie
Kindermann, G. (1995) · Archives of Gynecology and Obstetrics · doi:10.1007/bf02264797 · Cited by 3 · see citing works
Kontra endoskopische Ovarchirurgie
Kindermann, G. (1996) · Springer eBooks · doi:10.1007/978-3-642-79885-6_16 · Cited by 2 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
<p>The Pathogenesis and Prevention of Port-Site Metastasis in Gynecologic Oncology</p>
Gao, Q., Guo, L., & Wang, B. (2020) · Cancer Management and Research · doi:10.2147/cmar.s270881 · Cited by 60 · see citing works
Port site resection after laparoscopy in advance ovarian cancer surgery: time to abandon?
Lago, V., Gimenez, L., Matute, L., Padilla-Iserte, P., Cárdenas-Rebollo, J. M., Gurrea, M., Montero, B., Montoliu, G., & Domingo, S. (2019) · Surgical Oncology · doi:10.1016/j.suronc.2019.01.007 · Cited by 18 · see citing works
Port site endometrioma: a rare cause of abdominal wall pain following laparoscopic surgery
Siddiqui, Z. A., Husain, F., Siddiqui, Z., & Siddiqui, M. (2017) · BMJ Case Reports · doi:10.1136/bcr-2017-219291 · Cited by 14 · see citing works
Malignancy in Abdominal Wall Endometriosis: Is There a Way to Avoid It? A Systematic Review
Alaert, J., Lancelle, M., Timmermans, M., Tanos, P., Nisolle, M., & Karampelas, S. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13082282 · Cited by 9 · see citing works
- Authors
- Vergote, I., Marquette, S., Amant, F., Berteloot, P., & Neven, P.
- Affiliations
- Universitair Ziekenhuis Leuven (BE)
- ORCID
- Venue
- International Journal of Gynecological Cancer
- Publisher
- Elsevier BV
- Published
- 2005-09
- Volume
- 15
- Issue
- 5
- Pages
- 776-779
- ISSN
- 1048-891X (ISSN-L)
- OpenAlex
- W2016676868
- Cited by
- 133
- References
- 27
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 5 · 2023: 2 · 2022: 6 · 2021: 2 · 2020: 8 · 2019: 9 · 2018: 4 · 2017: 6 · 2016: 10 · 2015: 9 · 2014: 1 · 2013: 3 · 2012: 8
- FWCI
- 9.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- International Journal of Gynecological Cancer (publishedVersion)
- PubMed (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian cancer diagnosis and treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Endometrial and Cervical Cancer Treatments
- Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
- Keywords
- port-site metastases, advanced ovarian cancer, cytoreductive surgery, ascites, omental cake, stage III and IV ovarian cancer, prognosis
- MeSH terms
- Female, Humans, Neoplasm Metastasis, Neoplasm Staging, Ovarian Neoplasms, Laparoscopy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
