The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
The Many Faces of H89: A Review
Abstract
H89 is marketed as a selective and potent inhibitor of protein kinase A (PKA). Since its discovery, it has been used extensively for evaluation of the role of PKA in the heart, osteoblasts, hepatocytes, smooth muscle cells, neuronal tissue, epithelial cells, etc. Despite the frequent use of H89, its mode of specific inhibition of PKA is still not completely understood. It has also been shown that H89 inhibits at least 8 other kinases, while having a relatively large number of PKA‐independent effects which may seriously compromise interpretation of data. Thus, while recognizing its kinase inhibiting properties, it is advised that H89 should not be used as the single source of evidence of PKA involvement. H‐89 should be used in conjunction with other PKA inhibitors, such as Rp‐cAMPS or PKA analogs.
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Cites
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Younce, C. W., Burmeister, M. A., & Ayala, J. E. (2013) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00248.2012 · Cited by 134
Hu, P., Liu, J., Maita, I., Kwok, C., Gu, E., Gergues, M. M., Kelada, F., Phan, M., Zhou, J.-N., Swaab, D. F., et al. (2020) · The Journal of Neuroscience · doi:10.1523/jneurosci.2410-19.2020 · Cited by 71
Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol
Spolitu, S., Okamoto, H., Dai, W., Zadroga, J. A., Wittchen, E. S., Gromada, J., & Ozcan, L. (2019) · Circulation Research · doi:10.1161/circresaha.118.313648 · Cited by 64
Vitamin D Represses Dentin Matrix Protein 1 in Cementoblasts and Osteocytes
Nociti, F. H., Foster, B. L., Tran, A. B., Dunn, D., Presland, R. B., Wang, L., Bhattacharyya, N., Collins, M. T., & Somerman, M. J. (2014) · Journal of Dental Research · doi:10.1177/0022034513516344 · Cited by 35
Sunitinib Specifically Augments Glucose-Induced Insulin Secretion
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Metadata
- Authors
- Lochner, A., & Moolman, J. A.
- Venue
- Cardiovascular Drug Reviews
- Publisher
- Wiley
- Published
- 2006-09
- Volume
- 24
- Issue
- 3-4
- Pages
- 261-274
- ISSN
- 0897-5957 (ISSN-L)
- 1527-3466
- OpenAlex
- W1965993201
- Cited by
- 314
- References
- 59
- FWCI
- 3.32
- Type
- journal article
- Language
- en
- Open access
- closed
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