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Cited by 270

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Transcutaneous vagus nerve stimulation (t‐VNS) in pharmacoresistant epilepsies: A proof of concept trial

Stefan, Hermann, Kreiselmeyer, Gernot, Kerling, Frank, Kurzbuch, Katrin, Rauch, Christophe, Heers, Marcel, Kasper, Burkhard S., Hammen, Thilo, Rzonsa, Martina, Pauli, Elisabeth, Ellrich, Jens, Graf, Wolfgang, Hopfengärtner, Rüdiger·2012·Epilepsia

Abstract

Summary: To elucidate, in a pilot‐study, whether noninvasive transcutaneous vagus nerve stimulation (t‐VNS) is a safe and tolerable alternative treatment option in pharmacoresistant epilepsy. t‐VNS was applied to 10 patients with pharmacoresistant epilepsies. Stimulation via the auricular branch of the vagus nerve of the left tragus was delivered three times per day for 9 months. Subjective documentation of stimulation effects was obtained from patients’ seizure diaries. For a more reliable assessment of seizure frequency, we carried out prolonged outpatient video–electroencephalography (EEG) monitoring. In addition, computerized testing of cognitive, affective, and emotional functions was performed. Three patients aborted the study. Of the remaining seven patients, an overall reduction of seizure frequency was observed in five patients after 9 months of t‐VNS. The noninvasive t‐VNS stimulation is a safe and well‐tolerated method for relatively long periods, and might be an alternative treatment option for patients with epilepsy.

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Crossref · 10.1111/j.1528-1167.2012.03492.x

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Metadata

Authors
Stefan, H., Kreiselmeyer, G., Kerling, F., Kurzbuch, K., Rauch, C., Heers, M., Kasper, B. S., Hammen, T., Rzonsa, M., Pauli, E., Ellrich, J., Graf, W., & Hopfengärtner, R.
Venue
Epilepsia
Publisher
Wiley
Published
2012-05-03
Volume
53
Issue
7
Pages
e115-8
ISSN
  • 0013-9580 (ISSN-L)
  • 1528-1167
OpenAlex
W1544532631
Cited by
270
References
6
FWCI
8.87
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Transcutaneous vagus nerve stimulation (t‐VNS) in pharmacoresistant epilepsies: A proof of concept trial. https://app.cochat.ai/papers/10.1111/j.1528-1167.2012.03492.x
The paper
Stefan, H., Kreiselmeyer, G., Kerling, F., Kurzbuch, K., Rauch, C., Heers, M., Kasper, B. S., Hammen, T., Rzonsa, M., Pauli, E., Ellrich, J., Graf, W., & Hopfengärtner, R. (2012). Transcutaneous vagus nerve stimulation (t‐VNS) in pharmacoresistant epilepsies: A proof of concept trial. Epilepsia. https://doi.org/10.1111/j.1528-1167.2012.03492.x

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.