Cited by 195Neurotransmitter Receptor Influence on BehaviorAlcohol Consumption and Health EffectsSubstance Abuse Treatment and Outcomes

Alcohol preference and voluntary alcohol intakes of inbred rat strains and the National Institutes of Health heterogeneous stock of rats

Ting‐Kai, U, Lumeng, Lawrence·1984·Alcoholism: Clinical and Experimental Research

Abstract

The alcohol preference ratios and the daily free‐choice ethanol intakes (10% ethanol versus water) of the newly constituted National Institutes of Health (NIH) heterogeneous stock (N/Nih) rats, and of the eight inbred strains from which N/Nih derived, were measured. Among the eight inbred strains, ACI/N, WKY/N, F344/N, BUF/N, BN/ Ssn, WN/N, M520/N, and MR/N, the ACI exhibited the lowest preference and intakes and the MR and the M520 the highest The mean values for the N/Nih animals were intermediate among those of the inbred strains. The range of intake for the N/Nih rats was 0.06‐9.5 g/kg of body weight/day, indicating that they should serve as an appropriate foundation in selection studies for alcohol‐drinking preference.

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Crossref · 10.1111/j.1530-0277.1984.tb05708.x

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Authors
Ting‐Kai, U., & Lumeng, L.
Affiliations
Richard L. Roudebush VA Medical Center (US)
Corresponding author
Ting‐Kai, U
Venue
Alcoholism: Clinical and Experimental Research
Publisher
Wiley
Published
1984-09
Volume
8
Issue
5
Pages
485-486
ISSN
  • 0145-6008 (ISSN-L)
  • 1530-0277
OpenAlex
W2065955598
Cited by
195
References
0
Citations by year
2025: 1 · 2024: 2 · 2023: 4 · 2022: 8 · 2021: 2 · 2020: 2 · 2019: 5 · 2018: 7 · 2017: 4 · 2016: 4 · 2015: 2 · 2014: 4 · 2013: 3 · 2012: 3
FWCI
0.95
Type
journal article
Language
en
Open access
closed
Locations
  • Alcoholism Clinical and Experimental Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
alcohol preference, voluntary ethanol consumption, inbred rat strains, F344/N rats
MeSH terms
Alcohol Drinking, Alcoholism, Animals, Crosses, Genetic, Disease Models, Animal, Genotype, Humans, Rats, Inbred Strains, Rats

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