The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Diagnosis and Characteristics of Syncope in Older Patients Referred to Geriatric Departments
Open accessAbstract
OBJECTIVES: To test the applicability and safety of a standardized diagnostic algorithm in geriatric departments and to define the prevalence of different causes of syncope in older patients. DESIGN: Multicenter cross-sectional observational study. SETTING: In-hospital geriatric acute care departments and outpatient clinics. PARTICIPANTS: Two hundred forty-two patients (aged>or=65, mean+/-standard deviation=79+/-7, range 65-98) consecutively referred for evaluation of transient loss of consciousness to any of six clinical centers participating in the study. Of these, 11 had a syncope-like condition (5 transient ischemic attack; 6 seizures), and 231 had syncope (aged 65-74, n=71; aged>or=75, n=160). MEASUREMENTS: Protocol designed to define etiology and clinical characteristics of syncope derived from European Society of Cardiology Guidelines on syncope. RESULTS: No major complication occurred with use of the protocol. Neurally mediated was the more prevalent form of syncope in this population (66.6%). Cardiac causes accounted for 14.7% of all cases. The neuroreflex form of syncope (vasovagal, situational, and carotid sinus syndrome) was more common in younger than in older patients (62.3% vs 36.2%; P=.001), whereas orthostatic syncope was more frequent in the older than in the younger group (30.5% vs 4.2%; P<.001). In only 10.4% of cases, syncope remained of unexplained origin. After initial evaluation, a definite diagnosis was possible in 40.1% of the cases, and a suspected diagnosis was obtained in 57.9%. Syncope of suspected cardiac origin after initial evaluation was confirmed in 43.7% of cases, and neuromediated causes were confirmed in 83.5% of the cases. CONCLUSION: The protocol is applicable even beyond the age of 90 in geriatric departments. The standardized protocol is associated with a reduction in the frequency of unexplained syncope to about 10%.
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Metadata
- Authors
- Ungar, A., Mussi, C., Del Rosso, A., Noro, G., Abete, P., Ghirelli, L., Cellai, T., Landi, A., Salvioli, G., Rengo, F., Marchionni, N., Masotti, G., & for the Italian Group for the Study of Syncope in the Elderly
- Affiliations
- University of Modena and Reggio Emilia (IT)
- Corresponding author
- Ungar, Andrea
- Venue
- Journal of the American Geriatrics Society
- Publisher
- Wiley
- Published
- 2006-09-15
- Volume
- 54
- Issue
- 10
- Pages
- 1531-1536
- ISSN
- 0002-8614 (ISSN-L)
- 1532-5415
- OpenAlex
- W2152101062
- Cited by
- 127
- References
- 24
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 2 · 2023: 4 · 2022: 10 · 2021: 4 · 2019: 2 · 2018: 11 · 2017: 10 · 2016: 6 · 2015: 4 · 2014: 15 · 2013: 14 · 2012: 7
- FWCI
- 7.05
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Journal of the American Geriatrics Society (publishedVersion)
- PubMed (publishedVersion)
- Florence Research (University of Florence) (submittedVersion)
- IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- syncope, older adults, geriatric departments, diagnostic algorithm, syncope etiology, neurally mediated syncope, vasovagal syncope, carotid sinus syndrome, orthostatic syncope, cardiac syncope, transient ischemic attack, seizures, unexplained syncope
- MeSH terms
- Age Factors, Aged, Aged, 80 and over, Algorithms, Cross-Sectional Studies, Decision Trees, Female, Health Services for the Aged, Hospital Departments, Humans, Male, Middle Aged, Referral and Consultation, Syncope, Geriatric Assessment
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