Cited by 39Cardiac Arrhythmias and TreatmentsCardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Adenosine-sensitive atrial tachycardia

Abstract

Limited data suggest that adenosine termination of atrial tachycardia is uncommon. To investigate further the effect of adenosine on atrial tachycardia, adenosine (6-12 mg) was administered during sustained atrial tachycardia in 17 patients. All patients underwent electrophysiological study to exclude other mechanisms of supraventricular tachycardia. Mean patient age was 51 +/- 20 years (range 18-82 years). Seven patients had no structural heart disease. The mean atrial tachycardia cycle length was 390 +/- 80 msecs (range 260-580). Sustained atrial tachycardia was induced with atrial extrastimuli in 8 patients, and was either incessant at baseline or developed spontaneously during isoproterenol infusion in 9 patients. Adenosine terminated atrial tachycardia in 3 patients (18%), transiently suppressed atrial tachycardia in 4 patients (23%), and produced AV block without affecting tachycardia cycle length in the remaining 10 patients. Adenosine sensitivity was observed in 3 of 8 patients with tachycardias initiated and terminated by atrial extrastimuli, and in 4 of 9 patients with spontaneous, but not inducible tachycardias including 3 of 4 patients with isoproterenol facilitated tachycardias. Of multiple clinical and electrophysiological variables examined as potential predictors of adenosine sensitivity, only isoproterenol facilitation of spontaneous or inducible sustained tachycardia predicted adenosine sensitivity (P = 0.02). These observations suggest that adenosine-sensitive atrial tachycardia may be more common than previously recognized. Adenosine sensitivity does not appear to be specific for tachycardia mechanism and cannot be predicted by response to pacing. Atrial tachycardias dependent on beta-adrenergic stimulation are most likely to be terminated by adenosine.

Overview

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Crossref · 10.1111/j.1540-8159.1995.tb02520.x

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21 of 21 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 1

  1. Rosen MR., 1986, Is the response to programmed stimulation diagnostic of mechanisms for arrhythmias, Circulation, 73, II18

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Metadata

Authors
KALL, J. G., KOPP, D., OLSHANSKY, B., KINDER, C., O'CONNOR, M., CADMAN, C. S., & WILBER, D.
Affiliations
Loyola University Medical Center (US)
Corresponding author
KALL, JOHN G.
Venue
Pacing and Clinical Electrophysiology
Publisher
Wiley
Published
1995-02
Volume
18
Issue
2
Pages
300-306
ISSN
  • 0147-8389 (ISSN-L)
  • 1540-8159
OpenAlex
W2033632326
Cited by
39
References
21
Citations by year
2025: 2 · 2024: 2 · 2020: 1 · 2016: 3 · 2015: 6 · 2013: 1
FWCI
1.83
Type
journal article
Language
en
Open access
closed
Locations
  • Pacing and Clinical Electrophysiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Keywords
adenosine, atrial tachycardia, supraventricular tachycardia, atrioventricular block, beta-adrenergic stimulation, tachycardia termination
MeSH terms
Adenosine, Cardiac Pacing, Artificial, Electrocardiography, Female, Heart Block, Heart Conduction System, Humans, Isoproterenol, Male, Middle Aged, Tachycardia, Supraventricular, Catheter Ablation

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