The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Incidence of atrial fibrillation post-cavotricuspid isthmus ablation in patients with typical atrial flutter: left-atrial size as an independent predictor of atrial fibrillation recurrence
Abstract
INTRODUCTION: Atrial fibrillation and atrial flutter often coexist. The long-term occurrence of atrial fibrillation in patients presenting with atrial flutter alone is unknown. We report the long-term follow-up in patients who underwent cavotricuspid isthmus ablation for treatment of lone atrial flutter. METHODS AND RESULTS: Between January 1997 and June 2002, 632 patients underwent cavotricuspid isthmus ablation for the treatment of typical atrial flutter at the Cleveland Clinic Foundation. Three hundred sixty-three patients were included in this study and followed for a mean duration of 39 +/- 11 months. The mean duration of atrial flutter symptoms was 12 +/- 5 months. Mean left-atrial size and left-ventricular ejection fraction were 4.2 +/- 0.8 cm and 47 +/- 13%, respectively. After a mean follow-up time of 39 +/- 11 months, 13% (48 of 363) of the patients remained in sinus rhythm. Five percent (18 of 363) of patients experienced recurrence of atrial flutter only. Sixty-eight percent (246 of 363) experienced the onset of atrial fibrillation and 14% (51 of 363) experienced recurrence of atrial flutter and the new onset of atrial fibrillation. Overall, 82% (297 of 363) of the patients experienced new onset of drug refractory atrial fibrillation. Left-atrial size was a predictor of atrial fibrillation recurrence post-atrial flutter ablation. CONCLUSION: At long-term follow-up, approximately 82% of patients post-cavotricuspid isthmus ablation for atrial flutter developed drug refractory atrial fibrillation. This finding suggests that elimination of atrial flutter might delay, but does not prevent, atrial fibrillation. Evidence suggests both arrhythmias may share common triggers and such patients may derive a better long-term benefit from anatomical ablative treatment of atrial fibrillation as well.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“AF is more likely in patients having had AF episodes before ablation and in those with a dilated LA. 187”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [187]
Citations
Cites
Go, A. S., Hylek, E. M., Phillips, K. A., Chang, Y., Henault, L. E., Selby, J. V., & Singer, D. E. (2001) · JAMA · doi:10.1001/jama.285.18.2370 · Cited by 6,205
Impact of Atrial Fibrillation on the Risk of Death: The Framingham Heart Study
Benjamin, E. J., Wolf, P. A., D’Agostino, R. B., Silbershatz, H., Kannel, W. B., & Levy, D. (1998) · Circulation · doi:10.1161/01.cir.98.10.946 · Cited by 4,575
Radiofrequency ablation of the inferior vena cava-tricuspid valve isthmus in common atrial flutter
Cosío, F. G., López‐Gil, M., Goicolea, A., Arribas, F., & Barroso, J. G. (1993) · The American Journal of Cardiology · doi:10.1016/0002-9149(93)91014-9 · Cited by 550
Feld, G. K., FLECK, R. P., Chen, P., Boyce, K., Bahnson, T. D., Stein, J. B., Calisi, C. M., & Ibarra, M. (1992) · Circulation · doi:10.1161/01.cir.86.4.1233 · Cited by 526
Olgin, J. E., Kalman, J. M., Fitzpatrick, A. P., & Lesh, M. D. (1995) · Circulation · doi:10.1161/01.cir.92.7.1839 · Cited by 500
Radiofrequency catheter ablation of atrial arrhythmias. Results and mechanisms.
Lesh, M. D., Hare, G. F. V., Epstein, L. M., Fitzpatrick, A. P., Scheinman, M. M., Lee, R. J., Kwasman, M. A., Grogin, H. R., & Griffin, J. C. (1994) · Circulation · doi:10.1161/01.cir.89.3.1074 · Cited by 455
Natale, A., Newby, K. H., Pisanó, E., Leonelli, F., Fanelli, R., Potenza, D., Beheiry, S., & Tomassoni, G. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00635-5 · Cited by 414
Incidence and predictors of atrial flutter in the general population
Granada, J., Uribe, W., Chyou, P.-H., Maassen, K., Vierkant, R., Smith, P. N., Hayes, J., Eaker, E., & Vidaillet, H. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00982-7 · Cited by 375
Kalman, J. M., Olgin, J. E., Saxon, L. A., Fisher, W. G., Lee, R. J., & Lesh, M. D. (1996) · Circulation · doi:10.1161/01.cir.94.3.398 · Cited by 343
Radiofrequency ablation of atrial flutter. Efficacy of an anatomically guided approach.
Kirkorian, G., Moncada, E., Chevalier, P., Canu, G., Claudel, J.-P., Bellon, C., Lyon, L., & Touboul, P. (1994) · Circulation · doi:10.1161/01.cir.90.6.2804 · Cited by 190
Flagged first, then by citations
Cited by
Sorted by citations
Items 101–133 of 133
SCHWARTZMAN, D. S. (2010) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2010.01884.x · Cited by 1
Die Ablation ist die Therapie der Wahl bei typischem Vorhofflattern
Gwechenberger, M. (2014) · Journal für Kardiologie (Krause & Pachernegg GmbH)
[Interventional treatment of typical atrial flutter].
Velázquez‐Rodríguez, E. (2009) · PubMed
Cirugía de la taquicardia auricular regular. Mecanismos macrorreentrante y focal
Hornero, F., García-Cosío, F., & Gude, M. A. J. L. (2010) · Cirugía Cardiovascular · doi:10.1016/s1134-0096(10)70111-x
Walters, T. E., & Kalman, J. M. (2014) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.12446
Sarrias, A., Villuendas, R., Baranchuk, A. M., Bayés‐Genís, A., & Bayés‐Genís, A. (2015) · Heart Rhythm · doi:10.1016/j.hrthm.2015.01.006
Cavotricuspid Isthmus Anatomy Particularities in Atrial Flutter Ablation
Chiriac, L., Cristian, G., Bolohan, R., & Tintoiu, I. (2013) · Springer eBooks · doi:10.1007/978-1-4471-5316-0_36
Typical and Atypical Atrial Flutter
Nalliah, C. J., Kumar, S., Sanders, P., & Kalman, J. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-44733-1.00075-4
Isthmus-Dependent Atrial Flutter
Issa, Z. F., Miller, J. M., & Zipes, D. P. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-5998-1.00012-4
Lee, C. (2016) · International Journal of Arrhythmia · doi:10.18501/arrhythmia.2016.036
Miller, J. M., Das, M. K., & Zipes, D. P. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-18772-5.00021-3
OBSOLETE: Cardiac Arrhythmias in Heart Failure
Kalbfleisch, S. J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.99644-2
Have we reached the point of primary prevention for atrial fibrillation?
Sivasambu, B., & Berger, R. D. (2018) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.13503
Grossman, L., Katz, M., Beinart, R., & Nof, E. (2019) · Clinical Cardiology · doi:10.1002/clc.23193
Zemlyanskaya, O. A., & Станиславовна, К. Е. (2019) · Aterotromboz = Atherothrombosis · doi:10.21518/2307-1109-2019-1-62-71
PROTOCOL FOR PRESCRIBING ANTICOAGULANTS FOR ATRIAL FLUTTER: ARE ALL ISSUES RESOLVED?
Zotova, I. V. (2019) · Russian Medicine · doi:10.18821/0869-2106-2019-25-5-6-309-315
Typical and Atypical Atrial Flutter
Kumar, S., Sanders, P., & Kalman, J. M. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-2856-5.00074-1
Atrial Fibrillation after Radiofrequency Ablation of Type I Atrial Flutter.
Park, C., Gentil-Baron, P., & Shah, D. C. (2013) · Europe PMC (PubMed Central) · doi:10.4022/jafib.449
Sarabanda, Á. V. L. (2020) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20200316
Epi-endocardial asynchrony during atrial flutter followed by atrial fibrillation
van Staveren, L. N., van Schaagen, F. R. N., & de Groot, N. M. S. (2021) · HeartRhythm Case Reports · doi:10.1016/j.hrcr.2021.01.001
Risk factors associated with the development of post-ablation atrial fibrillation
Владимирович, Е. М., Ovchinnikov, Y. V., & Steklov, V. I. (2020) · Clinical Medicine (Russian Journal) · doi:10.30629/0023-2149-2020-98-7-498-502
Emel’yanenko, M. V., Ovchinnikov, Y. V., Steklov, V. I., & Emelyanenko, V. M. (2021) · Clinical Medicine (Russian Journal) · doi:10.30629/0023-2149-2020-98-9-10-685-690
Glover, B. M., & Brugada, P. (2016) · Springer eBooks · doi:10.1007/978-3-319-40818-7_7
Cardiac Arrhythmia in Heart Failure
Okabe, T., & Kalbfleisch, S. J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809657-4.99644-3
Issa, Z. F., Miller, J. M., & Zipes, D. P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-52356-1.00012-8
Hong, K. L., Glover, B. M., & Brugada, P. (2021) · Springer eBooks · doi:10.1007/978-3-030-74319-2_7
Khamnagadaev, I. A., Kovalev, I. A., Bulavina, I. A., Kokov, M. L., Zotov, A. S., Troitskiy, A. V., Khamnagadaev, I. I., Shkolnikova, M. A., & Сергеевич, К. Л. (2023) · Journal of clinical practice · doi:10.17816/clinpract114930
Yakushev, A. V., & Paratsii, O. Z. (2022) · Zaporozhye Medical Journal · doi:10.14739/2310-1210.2022.5.259489
Aker, A., Chernyaha-Royko, U., Sorokivskyy, M., & Kravchuk, B. B. (2024) · Heart Vessels and Transplantation · doi:10.24969/hvt.2024.473
The Never Old‐Fashioned Right Atrial Flutter Revisited
Costa, A. D., & Bénali, K. (2025) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.70082
Zhang, W., Wang, J., Zhu, M., Chen, H., WU, Z., & Hao, J. (2026) · Research Square · doi:10.21203/rs.3.rs-8687602/v1
Coleman, K. M., Leavitt, J., Prestandrea, L., Lam, B., Sullivan, I. R., Beccarino, N. J., Sharma, N., Gabriels, J. K., Ismail, H., Epstein, L. M., et al. (2026) · Heart Rhythm · doi:10.1016/j.hrthm.2026.04.005
Singireddy, S., Saravanabavanandan, R., Coombes, K., Ahsan, S., Shoura, S. J., Venugopal, D., Patel, Y., Bajaj, S., Shah, S., Mehrotra, A. P., et al. (2026) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.70478
Metadata
- Authors
- ELLIS, K., WAZNI, O., MARROUCHE, N., MARTIN, D., GILLINOV, M., McCARTHY, P., SAAD, E. B., BHARGAVA, M., SCHWEIKERT, R., SALIBA, W., BASH, D., ROSSILLO, A., ERCIYES, D., TCHOU, P., & NATALE, A.
- Affiliations
- Cleveland Clinic (US)
- Corresponding author
- NATALE, ANDREA
- ORCID
- Venue
- Journal of Cardiovascular Electrophysiology
- Publisher
- Wiley
- Published
- 2007-06-25
- Volume
- 18
- Issue
- 8
- Pages
- 799-802
- ISSN
- 1045-3873 (ISSN-L)
- 1540-8167
- OpenAlex
- W2060097624
- Cited by
- 134
- References
- 19
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 5 · 2023: 5 · 2022: 5 · 2021: 6 · 2020: 9 · 2019: 6 · 2018: 8 · 2017: 7 · 2016: 8 · 2015: 15 · 2014: 9 · 2013: 10 · 2012: 6
- FWCI
- 6.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Cardiovascular Electrophysiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Keywords
- atrial fibrillation, atrial flutter, cavotricuspid isthmus ablation, left atrial size, atrial fibrillation recurrence, drug-refractory atrial fibrillation, long-term follow-up, left ventricular ejection fraction, atrial fibrillation triggers
- MeSH terms
- Anti-Arrhythmia Agents, Atrial Fibrillation, Atrial Flutter, Female, Heart Atria, Humans, Male, Middle Aged, Ohio, Prognosis, Recurrence, Risk Factors, Sensitivity and Specificity, Tricuspid Valve, Reproducibility of Results, Comorbidity, Incidence, Catheter Ablation, Risk Assessment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review