The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Body Mass Index, Obstructive Sleep Apnea, and Outcomes of Catheter Ablation of Atrial Fibrillation
Open accessAbstract
Background: Obesity and obstructive sleep apnea (OSA) are associated with atrial fibrillation (AF). The effects of a large body mass index (BMI) and OSA on the results of radiofrequency catheter ablation (RFA) of AF are unclear. Objective: To evaluate the effect of BMI and OSA on the efficacy of RFA for AF. Methods: RFA was performed in 324 consecutive patients (mean age = 57 ± 11 years) with paroxysmal (234) or chronic (90) AF. OSA was diagnosed by polysomnography in 32 of 324 patients (10%) prior to ablation. Among the 324 patients, 18% had a normal BMI (<25 kg/m 2), 39% were overweight (BMI ≥ 25 kg/m 2 and <30 kg/m 2), and 43% were obese (≥30 kg/m 2). RFA was performed to eliminate complex fractionated atrial electrograms (CFAE) in the pulmonary vein antrum and left atrium. Results: At 7 ± 4 months after a single ablation procedure, 63% of patients without OSA and 41% with OSA were free from recurrent AF without antiarrhythmic drug therapy (P = 0.02). Multivariate analysis including variables of age, gender, type and duration of AF, OSA, BMI, left atrial size, ejection fraction, and hypertension demonstrated that OSA was the strongest predictor of recurrent AF (OR = 3.04, 95% CI: 1.11–8.32, P = 0.03). There was no association between BMI and freedom from recurrent AF. A serious complication occurred in 3 of 324 patients, with no relationship to BMI. Conclusions: OSA is a predictor of recurrent AF after RFA independent of its association with BMI and left atrial size. Obesity does not appear to affect outcomes after radiofrequency catheter ablation of AF.
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In the citing paper
“No significant difference in rate of recurrence was seen, however, in two very small studies712,728 and one large, retrospective cohort study.1217”
From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [728]
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In the citing paper
“A similar increased risk of AF recurrence was reported in several studies that did not systematically screen for OSA, but compared the risk of AF recurrence following ablation procedures in patients with a documented prior diagnosis of OSA to those without known OSA.728–730”
From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [728]
In the citing paper
“Obesity may increase the rate of AF recurrence after catheter ablation, [298][299][300][301] with obstructive sleep apnoea as an important potential confounder.”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [299]
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Obstructive Sleep Apnea as a Risk Factor for Stroke and Death
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Somers, V. K., Dyken, M. E., Clary, M. P., & Abboud, F. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118235 · Cited by 2,527
Obesity and the risk of new-onset atrial fibrillation
Wang, T. J. (2004) · JAMA · doi:10.1001/jama.292.20.2471 · Cited by 1,427
Risk Factors for Obstructive Sleep Apnea in Adults
Young, T. (2004) · JAMA · doi:10.1001/jama.291.16.2013 · Cited by 1,216
Echocardiographic predictors of nonrheumatic atrial fibrillation. The Framingham Heart Study.
Vaziri, S. M., Larson, M. G., Benjamin, E. J., & Levy, D. (1994) · Circulation · doi:10.1161/01.cir.89.2.724 · Cited by 1,073
Obstructive Sleep Apnea and the Recurrence of Atrial Fibrillation
Kanagala, R., Murali, N. S., Friedman, P. A., Ammash, N. M., Gersh, B. J., Ballman, K. V., M. Shamsuzzaman, A. S., & Somers, V. K. (2003) · Circulation · doi:10.1161/01.cir.0000068337.25994.21 · Cited by 983
(1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.17.1855 · Cited by 936
Left atrial volume as an index ofleft atrial size: a population-based study
Pritchett, A. M., Jacobsen, S. J., Mahoney, D. W., Rodeheffer, R. J., Bailey, K. R., & Redfield, M. M. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02981-9 · Cited by 583
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Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J. J., Blomström‐Lundqvist, C., Boriani, G., Castella, M., Dan, G.-A., Dilaveris, P., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa612 · Cited by 10,550
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P. F., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castellà, M., Diener, H., Heidbüchel, H., Hendriks, J., et al. (2016) · EP Europace · doi:10.1093/europace/euw295 · Cited by 6,438
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418
Calkins, H. G., Hindricks, G., Cappato, R., Kim, Y., Saad, E., Aguinaga, L., Akar, J. G., Badhwar, V., Brugada, J., Camm, A. J., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.05.012 · Cited by 2,794
Calkins, H., Kuck, K. H., Cappato, R., Brugada, J., Camm, A. J., Chen, S.-A., Crijns, H. J. G., Damiano, R. J., Davies, D. W., DiMarco, J., et al. (2012) · Europace · doi:10.1093/europace/eus027 · Cited by 2,722
Self-citation
Metadata
- Authors
- JONGNARANGSIN, K., CHUGH, A., GOOD, E., MUKERJI, S., DEY, S., CRAWFORD, T., SARRAZIN, J. F., KUHNE, M., CHALFOUN, N., WELLS, D., BOONYAPISIT, W., PELOSI, Jr., BOGUN, F., MORADY, F., & ORAL, H.
- Affiliations
- University of Michigan (US)
- Corresponding author
- JONGNARANGSIN, KRIT
- ORCID
- Venue
- Journal of Cardiovascular Electrophysiology
- Publisher
- Wiley
- Published
- 2008-07
- Volume
- 19
- Issue
- 7
- Pages
- 668-672
- ISSN
- 1045-3873 (ISSN-L)
- 1540-8167
- OpenAlex
- W2169161075
- Semantic Scholar
- 4c80f7ae98979785ff6faf5df2439737c93dd4eb
- Cited by
- 219
- References
- 20
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 7 · 2023: 8 · 2022: 15 · 2021: 9 · 2020: 11 · 2019: 7 · 2018: 15 · 2017: 21 · 2016: 11 · 2015: 12 · 2014: 15 · 2013: 22 · 2012: 21
- FWCI
- 8.98
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Journal of Cardiovascular Electrophysiology (publishedVersion)
- PubMed (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Keywords
- atrial fibrillation, obstructive sleep apnea, obesity, body mass index, radiofrequency catheter ablation, atrial fibrillation recurrence, complex fractionated atrial electrograms, left atrial size, ablation outcomes
- MeSH terms
- Atrial Fibrillation, Female, Humans, Male, Michigan, Middle Aged, Obesity, Risk Factors, Comorbidity, Body Mass Index, Prevalence, Treatment Outcome, Catheter Ablation, Risk Assessment, Sleep Apnea, Obstructive
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