The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Long‐Term Clinical Efficacy and Risk of Catheter Ablation for Atrial Fibrillation in the Elderly
Abstract
Introduction: The number of elderly patients with atrial fibrillation (AF) is increasing rapidly, and the safety and efficacy of catheter ablation in this demographic group has not been established. Methods: Over a 7‐year period we studied 1,165 consecutive patients undergoing 1,506 AF ablation procedures using a consistent ablation protocol that included proximal ostial pulmonary vein (PV) isolation and focal ablation of non‐PV AF triggers. Outcome was analyzed for three distinct age groups: <65 years (group 1; n = 948 patients), 65–74 years (group 2; n = 185 patients), and ≥75 years (group 3; n = 32 patients) based on the age at the initial procedure. Results: There was no significant difference in AF control (89% in group 1, 84% in group 2, and 86% in group 3, P = NS) during a mean follow‐up of 27 months. Major complication rates were also comparable (1.6% in group 1, 1.7% in group 2, 2.9% in group 3, P = NS) between the three groups. There was no difference in the left atrial size, percentage with left ventricular ejection fraction <50%, or percentage with paroxysmal versus more persistent forms of atrial fibrillation. However, older patients were more likely to be women (20% in group 1, 34% in group 2, and 56% in group 3, P < 0.001) and have hypertension and/or structural heart disease (56% in group 1 vs 68% in group 2 vs 88% in group 3; P < 0.001). There was a strong trend demonstrating that older patients were less likely to undergo repeat ablation (26% vs 27% vs 9%) to achieve AF control and more likely to remain on antiarrhythmic drugs (20% vs 29% vs 37%; P < 0.05). Conclusions: Elderly patients with AF undergoing catheter ablation therapy are represented by a higher proportion of women and have a higher incidence of hypertension/structural heart disease. To achieve a similar level of AF control, there appears to be no increased risk from the ablation procedure, but elderly patients are more likely to remain on antiarrhythmic drugs.
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Cites
Go, A. S., Hylek, E. M., Phillips, K. A., Chang, Y., Henault, L. E., Selby, J. V., & Singer, D. E. (2001) · JAMA · doi:10.1001/jama.285.18.2370 · Cited by 6,205
Cappato, R., Calkins, H., Chen, S.-A., Davies, W., Iesaka, Y., Kalman, J., Kim, Y.-H., Klein, G., Natale, A., Packer, D., et al. (2010) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.109.859116 · Cited by 2,852
Fuster, V., Rydén, L. E., Cannom, D. S., Crijns, H. J., Curtis, A. B., Ellenbogen, K. A., Halperin, J. L., Le Heuzey, J.-Y., Kay, G. N., Lowe, J. E., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.177292 · Cited by 2,805
Prevalence of atrial fibrillation in elderly subjects (the Cardiovascular Health Study)
Furberg, C. D., Psaty, B. M., Manolio, T. A., Gardin, J. M., Smith, V. E., & Rautaharju, P. M. (1994) · The American Journal of Cardiology · doi:10.1016/0002-9149(94)90363-8 · Cited by 1,096
Cited by
Calkins, H., Hindricks, G., Cappato, R., Kim, Y.-H., Saad, E. B., Aguinaga, L., Akar, J. G., Badhwar, V., Brugada, J., Camm, J., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.05.012 · Cited by 2,755
Self-citationCalkins, H., Kuck, K. H., Cappato, R., Brugada, J., Camm, A. J., Chen, S.-A., Crijns, H. J. G., Damiano, R. J., Davies, D. W., DiMarco, J., et al. (2012) · Europace · doi:10.1093/europace/eus027 · Cited by 2,722
Self-citationCalkins, H., Kuck, K. H., Cappato, R., Brugada, J., Camm, A. J., Chen, S.-A., Crijns, H. J. G., Damiano, R. J., Davies, D. W., DiMarco, J., et al. (2012) · Heart Rhythm · doi:10.1016/j.hrthm.2011.12.016 · Cited by 1,456
Self-citationPathophysiological mechanisms of atrial fibrillation: a translational appraisal
Schotten, U., Verheule, S., Kirchhof, P., & Goette, A. (2011) · Physiological Reviews · doi:10.1152/physrev.00031.2009 · Cited by 1,273
DAGRES, N., HINDRICKS, G., KOTTKAMP, H., SOMMER, P., GASPAR, T., BODE, K., ARYA, A., HUSSER, D., RALLIDIS, L. S., KREMASTINOS, D. T., et al. (2009) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2009.01493.x · Cited by 279
Metadata
- Authors
- ZADO, E., CALLANS, D. J., RILEY, M., HUTCHINSON, M., GARCIA, F., BALA, R., LIN, D., COOPER, J., VERDINO, R., RUSSO, A. M., DIXIT, S., GERSTENFELD, E., & MARCHLINSKI, F. E.
- Venue
- Journal of Cardiovascular Electrophysiology
- Publisher
- Wiley
- Published
- 2008-06
- Volume
- 19
- Issue
- 6
- Pages
- 621-626
- ISSN
- 1045-3873 (ISSN-L)
- 1540-8167
- OpenAlex
- W2125252722
- Cited by
- 174
- References
- 4
- FWCI
- 9.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- ZADO, E., CALLANS, D. J., RILEY, M., HUTCHINSON, M., GARCIA, F., BALA, R., LIN, D., COOPER, J., VERDINO, R., RUSSO, A. M., DIXIT, S., GERSTENFELD, E., & MARCHLINSKI, F. E. (2008). Long‐Term Clinical Efficacy and Risk of Catheter Ablation for Atrial Fibrillation in the Elderly. Journal of Cardiovascular Electrophysiology. https://doi.org/10.1111/j.1540-8167.2008.01183.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
