Cited by 134Atrial Fibrillation Management and OutcomesCardiac Arrhythmias and TreatmentsCardiac pacing and defibrillation studies

Prevalence, predictors and prognosis of atrial fibrillation early after pulmonary vein isolation: Findings from 3 months of continuous automatic ECG loop recordings

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JOSHI, SANDEEP, CHOI, ANDREW D., KAMATH, GANESH S., RAISZADEH, FARBOD, MARRERO, DANIEL, BADHEKA, APURVA, MITTAL, SUNEET, STEINBERG, JONATHAN S.·2009·Journal of Cardiovascular Electrophysiology

Abstract

Introduction: Following pulmonary vein isolation (PVI) for atrial fibrillation (AF), early recurrences are frequent, benign and classified as a part of a “blanking period.” This study characterizes early recurrences and determines implications of early AF following PVI. Methods and Results: Seventy‐two consecutive patients (59.8 ± 10.7 years, 69% male) were studied following PVI for paroxysmal or persistent AF. Subjects were fitted with an external loop recorder for automatic, continuous detection of AF recurrence for 3 months. AF prevalence was highest 2 weeks after PVI (54%) and declined to an eventual low of 22%. A significant number (488, 34%) of recurrences were asymptomatic; however, all patients with ≥1 AF event had ≥1 symptomatic event. No clear predictor of early recurrence was identified. Forty‐seven (65%) patients had at least 1 AF episode, predominantly (39 of 47 patients, 83%) within 2 weeks of PVI. Of the 33 patients who did not experience AF within the first 2 weeks, 85% (28/33) were complete responders (P = 0.03) at 12 months. Recurrence at any time within 3 months was not associated with procedural success or failure. Conclusions: Early AF recurrence peaks within the first few weeks after PVI, but continues at a lower level until the completion of monitoring. A blanking period of 3 months is justified to identify patients with AF recurrences that do not portend procedure failure. Freedom from AF in the first 2 weeks following ablation significantly predicts long‐term AF freedom.

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Crossref · 10.1111/j.1540-8167.2009.01506.x

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  • Very early AF events in the first 2 weeks may predict long-term failure, and AF during the blanking period may indicate greater likelihood of need for additional procedures or drugs.

    “Very early AF events in the first 2 weeks may predict long-term failure (Joshi et al., 2009), and AF during the blanking period may indicate greater likelihood of need for additional procedures or drugs (Arya et al., 2010).”

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Authors
JOSHI, S., CHOI, A. D., KAMATH, G. S., RAISZADEH, F., MARRERO, D., BADHEKA, A., MITTAL, S., & STEINBERG, J. S.
Affiliations
St. Luke's-Roosevelt Hospital Center (US)
Corresponding author
STEINBERG, JONATHAN S.
Venue
Journal of Cardiovascular Electrophysiology
Publisher
Wiley
Published
2009-10
Volume
20
Issue
10
Pages
1089-1094
ISSN
  • 1045-3873 (ISSN-L)
  • 1540-8167
OpenAlex
W2036327948
Cited by
134
References
15
Citations by year
2026: 4 · 2025: 5 · 2024: 4 · 2023: 6 · 2022: 4 · 2021: 6 · 2020: 5 · 2019: 3 · 2018: 9 · 2017: 15 · 2016: 15 · 2015: 9 · 2014: 11 · 2013: 10 · 2012: 11
FWCI
6.04
Type
journal article
Language
en
Open access
Locations
  • Journal of Cardiovascular Electrophysiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Keywords
atrial fibrillation, pulmonary vein isolation, catheter ablation, early recurrence, blanking period, external loop recorder, continuous ECG monitoring, asymptomatic recurrence, predictors of recurrence, long-term prognosis, procedural success
MeSH terms
Atrial Fibrillation, Female, Heart Conduction System, Humans, Male, Middle Aged, Prognosis, Pulmonary Veins, Risk Factors, Electrocardiography, Ambulatory, Prevalence, Treatment Outcome, Catheter Ablation, Risk Assessment

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