The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Prevalence and Predictive Factors of Eosinophilic Esophagitis in Patients Presenting With Dysphagia: A Prospective Study
Abstract
OBJECTIVES: Eosinophilic esophagitis (EE) is an increasingly recognized cause of dysphagia. We prospectively assessed the prevalence of EE using midesophageal biopsies in patients presenting with no endoscopically evident cause of dysphagia. We also aimed to determine the clinical and endoscopic factors predictive of EE in outpatients undergoing endoscopy for dysphagia. METHODS: Outpatients (18-60 yr of age) undergoing endoscopy for dysphagia at Mayo Clinic, Rochester between June 2005 and June 2006 were enrolled. Patients completed the validated Mayo Dysphagia Questionnaire (MDQ). Biopsies were obtained from the midesophagus if there was no endoscopically evident cause of dysphagia or there were endoscopic findings suggestive of EE. EE was defined as the presence of >20 eosinophils/high-power field. Logistic regression was performed to identify predictors of EE. RESULTS: Of 376 patients enrolled, 238 (63%) completed the MDQ and 222 (59%) had midesophageal biopsies; 33 (15%, 95% CI 6%-12%) had EE by biopsy. Ten of 102 (9.8%) patients who appeared endoscopically normal had EE by biopsy, while 8 of 21 (38%) patients with endoscopic changes suggestive of EE had EE on biopsy. Predictors of EE were younger age, endoscopic features suggestive of EE, absence of use of proton pump inhibitors, and a history of any food impaction for greater than 5 min. CONCLUSIONS: Midesophageal biopsies from normal-appearing mucosa should be obtained in all patients with unexplained solid food dysphagia; this may diagnose EE in about one in 10 cases.
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The endoscopic assessment of esophagitis: A progress report on observer agreement
Armstrong, D., Bennett, Jr., Blum, A., Dent, J., De Dombal, F., Galmiche, J., Lundell, L., Margulies, M., Richter, J., Spechler, S., et al. (1996) · Gastroenterology · doi:10.1053/gast.1996.v111.pm8698230 · Cited by 1,100
Eosinophilic Esophagitis: A 10-Year Experience in 381 Children
Liacouras, C. A., Spergel, J. M., Ruchelli, E., Verma, R., Mascarenhas, M., Semeao, E., Flick, J., Kelly, J., Brown–Whitehorn, T., Mamula, P., et al. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(05)00885-2 · Cited by 872
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Straumann, A., Spichtin, H.-P., Grize, L., Bucher, K. A., Beglinger, C., & Simon, H.-U. (2003) · Gastroenterology · doi:10.1053/j.gastro.2003.09.024 · Cited by 710
Histopathologic variability and endoscopic correlates in adults with eosinophilic esophagitis
Gonsalves, N., Policarpio-Nicolas, M., Zhang, Q., Rao, M. S., & Hirano, I. (2006) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2006.04.037 · Cited by 491
Intraepithelial Eosinophils: A New Diagnostic Criterion for Reflux Esophagitis
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Eosinophilic esophagitis in a patient with vigorous achalasia
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Eosinophilic esophagitis: Escalating epidemiology?
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Cited by
Eosinophilic esophagitis: Updated consensus recommendations for children and adults
Liacouras, C. A., Furuta, G. T., Hirano, I., Atkins, D., Attwood, S. E., Bonis, P. A., Burks, A. W., Chehade, M., Collins, M. H., Dellon, E. S., et al. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.02.040 · Cited by 2,073
Self-citationPrevalence of Eosinophilic Esophagitis in the United States
Dellon, E. S., Jensen, E. T., Martin, C. F., Shaheen, N. J., & Kappelman, M. D. (2014) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2013.09.008 · Cited by 444
Kanikowska, A., Janisz, S., Mańkowska-Wierzbicka, D., Gabryel, M., Dobrowolska, A., & Eder, P. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11247326 · Cited by 5
Metadata
- Authors
- Prasad, G. A., Talley, N. J., Romero, Y., Arora, A. S., Kryzer, L. A., Smyrk, T. C., & Alexander, J. A.
- Venue
- The American Journal of Gastroenterology
- Published
- 2007-12
- Volume
- 102
- Issue
- 12
- Pages
- 2627-2632
- ISSN
- 0002-9270 (ISSN-L)
- 1572-0241
- OpenAlex
- W2013785184
- Cited by
- 296
- References
- 22
- FWCI
- 12.54
- Type
- journal article
- Language
- en
- Open access
- closed
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- Prasad, G. A., Talley, N. J., Romero, Y., Arora, A. S., Kryzer, L. A., Smyrk, T. C., & Alexander, J. A. (2007). Prevalence and Predictive Factors of Eosinophilic Esophagitis in Patients Presenting With Dysphagia: A Prospective Study. The American Journal of Gastroenterology. https://doi.org/10.1111/j.1572-0241.2007.01512.x
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