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Cited by 189

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The role of the CcpA transcriptional regulator in carbon metabolism in Bacillus subtilis

Henkin, T·1996·FEMS Microbiology Letters
DOI 10.1016/0378-1097(95)00370-3
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Abstract

The CcpA protein has been identified as a key regulator of carbon metabolism in Bacillus subtilis. CcpA is a DNA binding protein in the LacI/GalR transcriptional repressor family, and genes which respond to CcpA contain common cis-acting target sequences (Ccp boxes). A number of pathways involved in carbon source utilization are repressed by CcpA, while at least one gene which is involved in excretion of excess carbon is activated by CcpA. Genes repressed by CcpA generally contain Ccp boxes within or downstream of the promoter, while ackA, which is activated by CcpA, contains Ccp boxes upstream of the promoter. It therefore appears that CcpA acts globally to direct carbon flow in B. subtilis.

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Metadata

Authors
Henkin, T.
Venue
FEMS Microbiology Letters
Publisher
Oxford University Press (OUP)
Published
1996-01-01
Volume
135
Issue
1
Pages
9-15
ISSN
0378-1097 (ISSN-L)
DOI
10.1016/0378-1097(95)00370-3
OpenAlex
W1995295185
Cited by
189
References
0
FWCI
5.82
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The role of the CcpA transcriptional regulator in carbon metabolism in Bacillus subtilis. https://app.cochat.ai/papers/10.1016/0378-1097(95)00370-3
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Henkin, T. (1996). The role of the CcpA transcriptional regulator in carbon metabolism in Bacillus subtilis. FEMS Microbiology Letters. https://doi.org/10.1016/0378-1097(95)00370-3

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.