The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
The genus Lactobacillus â a genomic basis for understanding its diversity
Abstract
The genus Lactobacillus is a diverse group that includes many species used in food production and preservation. Some lactobacilli are considered probiotic, conferring health benefits upon the host. The heterogeneity of this genus poses challenges and opportunities when characterizing or exploiting individual strains. To date, 10 Lactobacillus genome sequences have been published, and at least 11 more sequencing projects are ongoing. These studies will dramatically improve one's understanding of metabolic processes, bioprocessing capabilities and potential roles in health and well-being of the Lactobacilli. This review describes the current status of Lactobacillus genome sequence projects, highlights the major findings and summarizes functional genomics or comparative genomics studies. The genomic basis for the unusual diversity of this genus is discussed, and the potential for comparative genomics to rigorously extend phylogenetic analysis of the Lactobacilli is described.
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In the citing paper
“Some lactobacilli are considered probiotics due to their beneficial effects on host health [72,78].”
From Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions (2022) · cites this paper as [78]
In the citing paper
“Some lactobacilli are considered probiotics due to their beneficial effects on host health [72,78].”
From Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions (2022) · cites this paper as [78]
Citations
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Cited by
Sorted by citations
Genes and Molecules of Lactobacilli Supporting Probiotic Action
Lebeer, S., Vanderleyden, J., & De Keersmaecker, S. C. J. (2008) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00017-08 · Cited by 1,013
Immunomodulatory mechanisms of lactobacilli
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The extracellular biology of the lactobacilli
Kleerebezem, M., Pascal Hols, A., Bernard, E., Rolain, T., Zhou, M., Siezen, R. J., & Bron, P. A. (2009) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2009.00208.x · Cited by 399
Lactic Acid Bacteria: Food Safety and Human Health Applications
Ayivi, R. D., Gyawali, R., Krastanov, A. I., Aljaloud, S. O., Worku, M., Tahergorabi, R., da Silva, R. C., & Ibrahim, S. A. (2020) · Dairy · doi:10.3390/dairy1030015 · Cited by 432
The Genus Lactobacillus: A Taxonomic Update
Salvetti, E., Torriani, S., & Felis, G. E. (2012) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-012-9117-8 · Cited by 296
Metadata
- Authors
- Claesson, M. J., van Sinderen, D., & O'Toole, P. W.
- Affiliations
- University College Cork (IE)
- Corresponding author
- Claesson, Marcus J.
- ORCID
- Claesson, Marcus J.
- Venue
- FEMS Microbiology Letters
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-04
- Volume
- 269
- Issue
- 1
- Pages
- 22-28
- ISSN
- 0378-1097 (ISSN-L)
- 1574-6968
- OpenAlex
- W2000034666
- Cited by
- 154
- References
- 57
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 4 · 2023: 6 · 2022: 8 · 2021: 8 · 2020: 8 · 2019: 6 · 2018: 14 · 2017: 4 · 2016: 6 · 2015: 8 · 2014: 12 · 2013: 12 · 2012: 5
- FWCI
- 1.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- FEMS Microbiology Letters (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Science Foundation Ireland
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Keywords
- Lactobacillus, bacterial genome sequencing, comparative genomics, functional genomics, bacterial diversity, phylogenetic analysis, probiotics, metabolism
- MeSH terms
- Lactobacillus, Phylogeny, Genome, Bacterial, Sequence Analysis, DNA, Genomics, Biodiversity
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