The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Engineering bone: challenges and obstacles
Open accessAbstract
Repair of large bone defects is still a challenge for the orthopaedic, reconstructive and maxillo-facial surgeon. Availability of pluripotent stem cells from either autologous or allogenic sources and the potential of inducing the osteogenic phenotype is motivating exploration and development of custom-tailored materials known as "bioengineered bone constructs". In such cases, the clinical scenario involves either expansion of stem cells in monolayer and loading them into a porous scaffold prior to surgery or direct cell expansion within the scaffold, and implanting this novel construct back into the donor patient. In this review, we delineate, from an engineering perspective, the progress that has been made to date and the challenges remaining in successfully translating this promising (but not yet definitively established) approach from bench to the bed site.
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Cites
Biomaterials in Tissue Engineering
Hubbell, J. A. (1995) · Nature Biotechnology · doi:10.1038/nbt0695-565 · Cited by 1,060
SELF-REGULATION OF GROWTH IN THREE DIMENSIONS
Folkman, J., & Hochberg, M. (1973) · The Journal of Experimental Medicine · doi:10.1084/jem.138.4.745 · Cited by 829
Cited by
Bone Tissue Engineering: Recent Advances and Challenges
Amini, A. R., Laurencin, C. T., & Nukavarapu, S. P. (2012) · Critical Reviews in Biomedical Engineering · doi:10.1615/critrevbiomedeng.v40.i5.10 · Cited by 2,336
Normal Bone Anatomy and Physiology
Clarke, B. (2008) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.04151206 · Cited by 2,192
Marcacci, M., Kon, E., Moukhachev, V., Lavroukov, A., Kutepov, S., Quarto, R., Mastrogiacomo, M., & Cancedda, R. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0271 · Cited by 589
Li, L., Zhou, G., Wang, Y., Yang, G., Ding, S., & Zhou, S. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2014.10.015 · Cited by 314
Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression
Potier, E., Ferreira, E., Andriamanalijaona, R., Pujol, J.-P., Oudina, K., Logeart-Avramoglou, D., & Petite, H. (2007) · Bone · doi:10.1016/j.bone.2006.11.024 · Cited by 294
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Metadata
- Authors
- Logeart-Avramoglou, D., Anagnostou, F., Bizios, R., & Petite, H.
- Venue
- Journal of Cellular and Molecular Medicine
- Publisher
- Wiley
- Published
- 2005-01
- Volume
- 9
- Issue
- 1
- Pages
- 72-84
- ISSN
- 1582-1838 (ISSN-L)
- 1582-4934
- OpenAlex
- W2168902269
- Cited by
- 380
- References
- 2
- FWCI
- 19.76
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Logeart-Avramoglou, D., Anagnostou, F., Bizios, R., & Petite, H. (2005). Engineering bone: challenges and obstacles. Journal of Cellular and Molecular Medicine. https://doi.org/10.1111/j.1582-4934.2005.tb00338.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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